Results 21 to 30 of about 537,344 (241)
AhR Regulates Peptidoglycan-Induced Inflammatory Gene Expression in Human Keratinocytes
Journal of Innate Immunity, 2021 Bacterial peptidoglycan (PGN) stimulates toll-like receptor 2 (TLR2) on the surface of keratinocytes (KCs), triggering signaling pathways that promote an innate immune response.
Lanqi Wang +3 more
doaj +1 more source
Journal of Infection in Developing Countries, 2022 Introduction: Tuberculosis has been a concern of healthcare professionals due to the serious threats it poses on public health safety. However, regardless all the efforts, no appropriate goals for immunological diagnosis or tuberculosis treatment were ...
Eman A El-Masry +3 more
doaj +1 more source
Identification of single nucleotide polymorphisms in Toll-like receptor candidate genes associated with tuberculosis infection in water buffalo (Bubalus bubalis) [PDF]
, 2014 Toll-like receptors play a key role in innate immunity by recognizing pathogens and activating appropriate responses. Pathogens express several signal molecules (pathogen-associated molecular patterns, PAMPs) essential for survival and pathogenicity ...
Acutis, Pier Luigi +11 more
core +1 more source
Toll-like receptor (TLR) 2 and TLR4 gene expression in canine heart [PDF]
, 2007 Toll-like receptors (TLRs) are archetypal pattern recognition receptors of immediate importance for an efficacious innate immune response. TLRs exhibit marked differential tissue activity and their levels within a discrete cell type can be highly dynamic.
Blecha, Frank +2 more
core +2 more sources
Peptidoglycan- and Lipoteichoic Acid-induced Cell Activation Is Mediated by Toll-like Receptor 2*
Journal of Biological Chemistry, 1999 The life-threatening complications of sepsis in humans are elicited by infection with Gram-negative as well as Gram-positive bacteria. Recently, lipopolysaccharide (LPS), a major biologically active agent of Gram-negative bacteria, was shown to mediate ...
R. Schwandner +4 more
semanticscholar +1 more source
Collaborative Induction of Inflammatory Responses by Dectin-1 and Toll-like Receptor 2
Journal of Experimental Medicine, 2003 Toll-like receptors (TLRs) mediate recognition of a wide range of microbial products including lipopolysaccharides, lipoproteins, flagellin, and bacterial DNA, and signaling through TLRs leads to the production of inflammatory mediators.
Benjamin N Gantner +4 more
semanticscholar +1 more source
Revista do Instituto de Medicina Tropical de São Paulo, 2015 There are few studies on the role of innate immune response in dermatophytosis. An investigation was conducted to define the involvement of Toll-Like Receptors (TLRs) 2 and 4 in localized (LD) and
Cristiane Beatriz de Oliveira +8 more
doaj +1 more source
Distribution of Toll‐like receptor 1 and Toll‐like receptor 2 in human lymphoid tissue [PDF]
Immunology, 2003 SummaryTo determine how distinct receptors of the immune system can contribute to innate immunity, we investigated the pattern of Toll‐like receptor 1 (TLR1) and TLR2 expression in human lymphoid tissue. We found that TLR1 and TLR2 were co‐expressed on cells of the innate immune system, including macrophages and dendritic cells.
Maria-Teresa, Ochoa +5 more
openaire +2 more sources
Iranian Journal of Allergy, Asthma and Immunology, 2019 Studies have shown that toll-like receptors (TLRs) play some important roles in reproductive processes such as ovulation, spermatogenesis, sperm capacitation, fertilization, and pregnancy to the best of our knowledge, no study has evaluated the ...
Nasrin Sereshki +5 more
doaj +1 more source
The Immunological Changes in the Skin of BALC/c Mice with Disseminated Acanthamoebiasis
Pathogens, 2023 Toll-like receptors (TLR) are involved in the recognition of numerous pathogens, including Acanthamoeba spp. Thanks to this, it is possible for immune cells to recognize microorganisms and trigger the body’s innate immune response.
Agnieszka Wojtkowiak-Giera +7 more
doaj +1 more source