Results 41 to 50 of about 363,419 (348)

The expression of TLR2 and TLR4 in the kidneys and heart of mice infected with Acanthamoeba spp.

Parasites & Vectors, 2020
Background Acanthamoeba spp. are cosmopolitan protozoans that cause infections in the brain, as well as extracerebral infections in the cornea, lungs and skin.
Karolina Kot, Danuta Kosik-Bogacka, Agnieszka Wojtkowiak-Giera, Agnieszka Kolasa-Wołosiuk, Natalia Łanocha-Arendarczyk   +4 more
doaj   +1 more source

c-Jun N-Terminal Kinase in Inflammation and Rheumatic Diseases. [PDF]

, 2012
The c-Jun N-terminal kinases (JNKs) are members of the mitogen-activated protein kinase (MAPK) family and are activated by environmental stress. JNK is also activated by proinflammatory cytokines, such as TNF and IL-1, and Toll-like receptor ligands ...
Firestein, Gary S, Guma, Monica
core   +1 more source

Regulatory T cells isolated from endometriotic peritoneal fluid express a different number of Toll-like receptors

Einstein (São Paulo), 2020
Objective To analyze and compare the expression of Toll-like receptors by regulatory T cells present in the peritoneal fluid of patients with and without endometriosis.
Camila Hernandes, Bárbara Yasmin Gueuvoghlanian-Silva, Vitor Ulisses Monnaka, Natalia Mazini Ribeiro, Welbert de Oliveira Pereira, Sérgio Podgaec   +5 more
doaj   +2 more sources

The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling [PDF]

, 2008
The kinases MSK1 and MSK2 are activated 'downstream' of the p38 and Erk1/2 mitogen-activated protein kinases. Here we found that MSK1 and MSK2 were needed to limit the production of proinflammatory cytokines in response to stimulation of primary ...
A Cuenda, A Soloaga, A Sommer, Andrew Wingate, B Echtenacher, B Echtenacher, BG Stiles, C Platzer, CA Gogos, Claire E Monk, Claus Johansen, D Rittirsch, DM Dambach, ER Ottosen, F Hildebrand, FY Liew, GR Wiggin, GY Song, H Chi, J Bain, J Darragh, J Han, J Rouse, J Simon C Arthur, Jin Mo Park, JM Park, Joanne Darragh, Joanne McIlrath, JS Arthur, JS Arthur, Julia M Carr, KV Salojin, Lars Iversen, M Brook, M Hammer, M Saraiva, ML Steinhauser, MS Lee, NC Riedamann, NW Freshney, Olga Ananieva, OM Peck-Palmer, P Chen, PC Cheung, PJ Murray, Q Zhao, R Kuhn, Rachel Toth, SE Moreno, SJ O'Keefe, SM Miggin, SQ Latifi, Susana G Santos, T Kawai, T Lang, T van der Poll, VA Beardmore, VS Carl, WJ Hubbard, X Zhang, Y Kalechman, YJ Kang   +61 more
core   +3 more sources

Toll‐like receptor‐2 exacerbates murine acute viral hepatitis [PDF]

Immunology, 2016
SummaryViral replication in the liver is generally detected by cellular endosomal Toll‐like receptors (TLRs) and cytosolic helicase sensors that trigger antiviral inflammatory responses. Recent evidence suggests that surface TLR2 may also contribute to viral detection through recognition of viral coat proteins but its role in the outcome of acute viral
Bleau, C., Burnette, M., Filliol, Aveline, Piquet-Pellorce, Claire, Samson, Michel, Lamontagne, Lucie   +5 more
openaire   +2 more sources

Induction Effects Of Bacteroides Fragilis Derived Outer Membrane Vesicles On Toll Like Receptor 2, Toll Like Receptor 4 Genes Expression And Cytokines Concentration In Human Intestinal Epithelial Cells

Cell Journal, 2018
Objective Gastrointestinal (GI) tract, like other mucosal surface, is colonized with a microbial population known as gut microbiota. Outer membrane vesicles (OMVs) which are produced by gram negative bacteria could be sensed by Toll like receptors (TLRs)
Sara Ahmadi Badi, Shohreh Khatami, Shiva Irani, Seyed Davar Siadat   +3 more
doaj   +1 more source

Toll-like receptor 2 suppresses Toll-like receptor 9 responses in Peyer's patch dendritic cells

Immunobiology, 2015
In the intestine, immune responses to commensal microbes should be regulated precisely. This regulation is achieved partly by dendritic cells (DCs), which recognize microbes through Toll-like receptors (TLRs). Although TLR responses have been intensely studied, cross-talk between individual TLRs remains unclear.
Ryutaro, Kotaki, Shun-ichi, Wajima, Aya, Shiokawa, Satoshi, Hachimura   +3 more
openaire   +2 more sources

Dependence of interleukin-10 quantitative level from genetic polymorphism of toll-like receptors 2 (rs 5743708) in patients with herpes zoster

Journal of Education, Health and Sport, 2019
Background. Herpes zoster is urgent problem of the present time, due to increased incidence of severe course with complications in immunocompetent persons, which leads to decrease quality of life and disability.
N. V. Onishchenko, O. V. Riabokon
doaj   +1 more source

Toll-like Receptor 2 Facilitates Oxidative Damage-Induced Retinal Degeneration

Cell Reports, 2020
Summary: Retinal degeneration is a form of neurodegenerative disease and is the leading cause of vision loss globally. The Toll-like receptors (TLRs) are primary components of the innate immune system involved in signal transduction.
Kelly Mulfaul, Ema Ozaki, Nilisha Fernando, Kiva Brennan, Kathleen R. Chirco, Emma Connolly, Chris Greene, Arvydas Maminishkis, Robert G. Salomon, Mikhail Linetsky, Riccardo Natoli, Robert F. Mullins, Matthew Campbell, Sarah L. Doyle   +13 more
doaj   +1 more source

Soluble toll like receptor 2 (TLR-2) is increased in saliva of children with dental caries [PDF]

, 2014
Background Dental caries is the most common microbial disease affecting mankind. Caries risk assessment methods, identification of biomarkers and vaccine development strategies are being emphasized to control the incidence of the largely preventable ...
Blackburn, Corinne, Chin, Judith, Srinivasan, Mythily, Zhao, Alyssa   +3 more
core   +1 more source