Results 81 to 90 of about 100,532,293 (204)
Novel mutations in the toll like receptor genes cause hyporesponsiveness to Mycobacterium avium subsp. paratuberculosis infection [PDF]
, 2008 Toll like receptors play a central role in the recognition of pathogen associated molecular patterns (PAMPs). Mutations in TLR1, TLR2 and TLR4 genes may change the PAMP reorganization ability which causes altered responsiveness to the bacterial pathogens.
Rostislav Skrabana +6 more
core
Innate immune activation in experimental autoimmune myocarditis [PDF]
, 2007 Dilated cardiomyopathy (DCM) is a leading cause of heart failure and frequently results from postinfectious autoimmunity. Its pathophysiology is modeled by experimental autoimmune myocarditis (EAM), a CD4+ T-cell mediated murine model of ...
Marty, René Roger
core +1 more source
Toll-like receptor and JAK-STAT signaling pathway.
, 2017 Allobathynella bangokensis transcripts coding for the corresponding enzymes of the A) Toll-like receptor and B) JAK-STAT signaling pathways from the KEGG database. The annotated enzymes are shown in pink boxes.
Bo-Mi Kim (314453) +8 more
core +1 more source
Frontiers in Physiology, 2018 Peritoneal dialysis (PD) is an essential daily life-saving treatment for end-stage renal failure. PD therapy is limited by peritoneal inflammation, which leads to peritoneal membrane failure as a result of progressive fibrosis.
Anne-Catherine Raby, Mario O. Labéta
doaj +1 more source
International Journal of Clinical and Biomedical Research, 2016 Aim: The aim of the present study was to analyze the expression level and localization of Toll-like receptor 2 and Toll-like receptor 4 in gingival samples of healthy and chronic periodontitis subjects by indirect immunofluorescence technique. Methods: Gingival tissue samples were obtained from 25 healthy individuals and 25 chronic periodontitis ...
Romaladin, D’Souza +3 more
openaire +4 more sources
Frontiers in Cellular and Infection Microbiology, 2019 Cutaneous leishmaniasis (CL) caused by infection with Leishmania braziliensis is characterized by an exaggerated inflammatory response that controls the parasite burden, but also contributes to pathology. While myeloid cells are required to eliminate the
Ludmila P. Polari +10 more
doaj +1 more source
BN nanospheres as CpG ODN carriers for activation of toll-like receptor 9 [PDF]
, 2011 For the first time, we demonstrated BN nanospheres (BNNSs) can interact with biomolecules and deliver unmethylated cytosine-phosphate-guanine oligodeoxynucleotides (CpG ODNs) into cells to activate toll-like receptor 9 (TLR9), which is a very important ...
Golberg, Dmitri +13 more
core +2 more sources
Determinants of innate immune responses to mycobacteria [PDF]
, 2012 Includes bibliographical references.Innate cells such as macrophages, monocytes, myeloid dendritic cells and granulocytes recognise mycobacteria and initiate immune responses such as phagocytosis, cytokine production and expression of maturation markers.
Shey, Muki Shehu
core +1 more source
Antagonizing Neuronal Toll-like Receptor 2 Prevents Synucleinopathy by Activating Autophagy
Cell Reports, 2015 Impaired autophagy has been implicated in many neurodegenerative diseases, such as Parkinson’s disease (PD), and might be responsible for deposition of aggregated proteins in neurons. However, little is known about how neuronal autophagy and clearance of
Changyoun Kim +9 more
doaj +1 more source
Türk Biyokimya DergisiAcute appendicitis (AA) is the primary cause of urgent surgery. The goal of this case-control study was to establish the possible associations of tumor necrosis factor (TNF), toll-like receptor-2 (TLR2), and toll-like receptor-4 (TLR4) gene polymorphisms
Aslan Yusuf Ertugrul +5 more
doaj +1 more source