Results 161 to 170 of about 213,803 (247)

Inorganic Arsenic Induces Elevated p53 Levels with Altered Functionality Impacting the Expression of Toll-like Receptor 3 and Other Target Genes in Immortalized Prostate Epithelial Cells. [PDF]

Int J Mol Sci
Pacheco-Castillo NC, Gómez-Montalvo J, Olivares-Illana V, Recillas-Targa F, Tokar EJ, Avendaño-Vázquez SE, Escudero-Lourdes C.   +6 more
europepmc   +1 more source

Maintaining trust in uncertain times: Funding pauses and the ethical cost to community‐engaged research

American Journal of Community Psychology, EarlyView.
Abstract Federal funding pauses, once considered rare, are increasingly disrupting the stability and continuity of community‐engaged research. Even projects with active, awarded grants are experiencing the strain of funding uncertainty, raising substantive concerns among research teams and community partners. These disruptions extend beyond operational
Brynn E. Sheehan
wiley   +1 more source

Poly (I:C)-induced inflammation requires the activation of toll-like receptor 3/Ca²⁺/CaMKII/pannexin 1-dependent signaling. [PDF]

Theranostics
Salgado M, Sepúlveda-Arriagada V, Konar-Nié M, García-Robles MA, Sáez JC.   +4 more
europepmc   +1 more source

Effect of Red Blood Cell Transfusion on Inflammatory and Angiogenic Pathways in Patients With Sickle Cell Disease

American Journal of Hematology, EarlyView.
ABSTRACT Sickle cell disease (SCD) is a chronic inflammatory state, characterized by increased plasma values of inflammatory and angiogenic proteins. Although red blood cell (RBC) transfusion is known to have immunomodulatory effects in other conditions, its potential effects on the inflammatory state in SCD remain largely unknown.
Lydian A. de Ligt, Sanjay R. Thakoerdin, Maud Zwolsman, Gaby Stegemann, Hanke Matlung, Taco W. Kuijpers, Bart J. Biemond, Karin Fijnvandraat, Robin van Bruggen, Erfan Nur   +9 more
wiley   +1 more source

Toll-like receptor 3-stimulation and aggregate-formation synergistically enhances anti-inflammatory activity of feline mesenchymal stem cells. [PDF]

J Vet Sci
Fujimoto Y, Hatoya S, Sugiura K, Tabata Y.   +3 more
europepmc   +1 more source

Increased alcohol self-administration following repeated Toll-like receptor 3 agonist treatment in male and female rats. [PDF]

Pharmacol Biochem Behav, 2022
Lovelock DF, Randall PA, Van Voorhies K, Vetreno RP, Crews FT, Besheer J.   +5 more
europepmc   +1 more source

The Diagnosis That Arrived Decades Late: Living Without and Then With Myhre Syndrome

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre syndrome (MIM #139210) is a rare multisystem disorder first described in 1981, characterized by short stature, neurodevelopmental delay, joint contractures, and cardiopulmonary complications. Its molecular basis, recurrent pathogenic variants in SMAD4, was not discovered until 2011. This narrative is based on a review of medical records,
Abdallah F. Elias
wiley   +1 more source

Toll-Like receptor 3-mediated interferon-β production is suppressed by oncostatin m and a broader epithelial-mesenchymal transition program. [PDF]

Breast Cancer Res
Chernosky NM, Tamagno I, Polak KL, Chan ER, Yuan X, Jackson MW.   +5 more
europepmc   +1 more source

Conjunctival Expression of Toll-Like Receptor 3 Plays a Pathogenic Role in the Formation of Ultraviolet Light-Induced Pterygium. [PDF]

Invest Ophthalmol Vis Sci, 2021
Lai CC, Tseng SH, Hsu SM, Huang YT, Shieh CC.   +4 more
europepmc   +1 more source