Results 191 to 200 of about 14,758,329 (299)

Toll-Like Receptors in the Mechanism of Hexabromocyclododecane-Induced Production of Pro-Inflammatory Cytokines. [PDF]

J Appl Toxicol
Zhu W, Seaton-Terry A, Townsend B, Hunter Z, Falconer-Turner A, Shahid SR, Whalen M.   +6 more
europepmc   +1 more source

Biomimetic Scaffold‐Based 3D Models for Decoding Cancer Biology and Advancing Therapy

Advanced Science, EarlyView.
A timeline of the research history of 3D biomimetic scaffold materials and platforms. With advances in biomimetic materials and 3D scaffold technologies, their functional scope has expanded from mimicking basic physical and biochemical properties to increasingly replicating complex pathophysiological processes.
Haitao Zhao, Yuechen Han, Jie Li, Peng Luo, Lin Qi, Zhiwei Xia, Xiaosong Li, Quan Cheng, Chenshen Huang, Wantao Wu, Hao Zhang   +10 more
wiley   +1 more source

Lipopolysaccharide promotes bladder cancer immunosuppression by disrupting the Tfh/Tfr balance through TLR4 signaling. [PDF]

Am J Transl Res
Peng B, Wang Y, Li H, Zhuang C, Guan R, Zhang H, Wan L.   +6 more
europepmc   +1 more source

Pathological Signal‐Responsive Nanoplatforms for Sepsis: Integrating Biomarker Sensing With Spatiotemporal Drug Delivery and Immunomodulation

Advanced Science, EarlyView.
Biomarker‐triggered nanoplatforms transform sepsis therapy by coupling pathological sensing with precision drug release. This review reveals how microenvironment‐responsive nanomedicines enable stage‐specific intervention, improve therapeutic efficacy, and minimize systemic toxicity, while highlighting emerging opportunities for AI‐assisted and ...
Yukun Liu, Kang Wang, Kwet Kyawl Yan, Zhikai Xu, Xuan Zhao, Xiangjun Bai, Zhanfei Li, Yuchang Wang   +7 more
wiley   +1 more source

Oxidized Low-Density Lipoprotein Enhances Toll-like Receptor-Mediated Osteoclastogenic Responses in the Absence of Exogenous RANKL: Implications for Inflammatory Osteoclastogenesis in Periodontitis. [PDF]

Medicina (Kaunas)
Ohgi K, Kajiya H, Nagaoka Y, Yamamoto N, Maruo N, Yamato H, Tsuchimochi N, Nakagami M, Fujioka A, Yoshinaga Y.   +9 more
europepmc   +1 more source

Molecular Bases and Genetic Design of Rice Disease Resistance for Optimized Yield and Sustainable Agriculture

Advanced Science, EarlyView.
This study integrates rice immune perception, signal transduction, and resistance output into a multi‐omics framework. By combining high‐throughput sequencing, phenomics, and AI‐assisted design with marker‐assisted selection, gene editing, and rapid domestication, we aim to accelerate the precise breeding of disease‐resistant rice varieties by ...
Xinyue Hou, Yuanjiang Cui, Chaoqing Ding, Qian Qian, Deyong Ren   +4 more
wiley   +1 more source

Extension Economists: Valued in Mission, Penalized in Practice

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT As the public engagement arm of the land‐grant mission, we argue that Extension faculty in US agricultural economics departments face an identity crossroads as they struggle for institutional support. Specifically, we argue that Extension economists function as boundary‐spanning professionals within academic structures that often devalue ...
Trey Malone, Craig W. Carpenter, Courtney Bir, Andrew J. Van Leuven, Rebecca Wasserman‐Olin, Wendong Zhang   +5 more
wiley   +1 more source

Transcriptomic analysis reveals members and expression characteristics of innate immunity genes in Chinese scorpion Mesobuthus martensii. [PDF]

Sci Rep
Wang H, Zhao Y, Yang Z, Zhang F, Di Z.
europepmc   +1 more source

The psychosocial toll of Dublin III on asylum seekers in the Netherlands

American Journal of Community Psychology, EarlyView.
Abstract The Dublin III Regulation determines which EU Member State is responsible for examining asylum claims, but its implementation carries significant consequences for those subjected to it. This study examines how Dublin III, as implemented in the Netherlands, affects asylum seekers' psychosocial wellbeing using Silove′s Adaptation and Development
Imen El Amouri
wiley   +1 more source

Vaccine diluent affects expression levels of immune related genes in caecal tonsils of layer chickens vaccinated with live attenuated <i>Salmonella</i> Typhimurium vaccine. [PDF]

Vet Q
Khan S, McWhorter AR, Andrews DM, Underwood GJ, Chousalkar KK.   +4 more
europepmc   +1 more source