Results 111 to 120 of about 310,367 (307)

One special question to start with: can HIF/NFkB be a target in inflammation? [PDF]

, 2015
Hypoxia and Inflammation are strictly interconnected with important consequences at clinical and therapeutic level. While cell and tissue damage due to acute hypoxia mostly leads to cell necrosis, in chronic hypoxia, cells that are located closer to ...
CARNEVALE, ILARIA, DE SANTIS, Elena, Limana, F, Perrone, Ga, POLLETTA, LUCIA, RUNCI, ALESSANDRA, RUSSO, Matteo Antonio, SANSONE, LUIGI, TAFANI, MARCO   +8 more
core   +1 more source

Toll-Like Receptors, Their Ligands, and Atherosclerosis

The Scientific World Journal, 2011
Atherosclerosis is a disease characterized by inflammation in the arterial wall. Atherogenesis is dependent on the innate immune response involving activation of Toll-like receptors (TLRs) and the expression of inflammatory proteins.
Conrad P. Hodgkinson, Shu Ye
doaj   +1 more source

Unlocking NIR‐II Photoluminescence in 2D Copper Tetrasilicate Nanosheets through Flame Spray Synthesis

Advanced Materials, EarlyView.
A flame‐spray‐pyrolysis method is presented to synthesize ultra‐bright CTS nanosheets with tunable NIR‐II emission. Achieving quantum yields up to 34%, these materials support high‐speed imaging and enable super‐resolution in vivo applications such as transcranial microcirculation mapping and macrophage tracking.
Robert Nißler, Quanyu Zhou, Björn Hill, Sabrina L.J. Thomä, Lukas R.H. Gerken, Aurelio Borzi, Kevin Roost, Benjamin Mächler, Xosé Luís Deán‐Ben, Antonia Neels, Sebastian Kruss, Daniel Razansky, Inge K. Herrmann   +12 more
wiley   +1 more source

CLINICAL SIGNIFICANCE OF Toll2, Toll4, CD14, AND HLA-DR EXPRESSION ON THE MONOCYTES IN PATIENTS WITH SEPSIS

Медицинская иммунология, 2015
Expression of Toll-like receptors (TLRs) on myeloid cells is of key importance for induction of systemic reactions caused by bacterial damage, and activation mechanisms of innate immune response. The study included thirty-six patients with sepsis in whom
V. A. Lazanovich, E. V. Markelova, G. A. Smirnov, T. P. Smolina   +3 more
doaj   +1 more source

Cutting Edge: Heat Shock Protein 60 Is a Putative Endogenous Ligand of the Toll-Like Receptor-4 Complex [PDF]

, 2000
Koji Ohashi, Volker Burkart, Stefanie B. Flohé, Hubert Kolb   +3 more
openalex   +1 more source

Rational Development of a Novel Emulgel Adjuvant for Single‐Shot Effective Vaccination: A Multivariate Analysis Approach

Advanced Materials, EarlyView.
Using multivariate analysis, a novel emulgel adjuvant is developed by combining key nanoemulsion formulation variables–hydrogel trapping, small globule size, and mannide monooleate surfactant–achieving 10× greater immunogenicity than MF59 in mice after a single shot.
Ahmed O. Shalash, Waleed M. Hussein, Ummey J. Nahar, Jingwen Wang, Lantian Lu, Armira Azuar, Jolynn J. E. Kiong, Prashamsa Koirala, Zeinab G. Khalil, Istvan Toth   +9 more
wiley   +1 more source

Biomimetic Cell Membrane‐Coated Scaffolds for Enhanced Tissue Regeneration

Advanced Materials, EarlyView.
This review examines the development and use of cell membrane‐coated scaffolds in tissue engineering. Bioinspired phospholipid and glycocalyx coatings enhance anti‐fouling, anti‐thrombogenic, and selective molecular recognition properties. Native cell membrane coatings further support cell‐specific interactions, immune modulation, and reduced bacterial
Carmen Alvarez‐Lorenzo, Alejandro Ramirez‐Romero, Diana Peixoto, Maria Vivero‐Lopez, Isabel Rodríguez‐Moldes, Angel Concheiro   +5 more
wiley   +1 more source

Creating a new Ontology: a Modular Approach [PDF]

, 2010
Creating a new Ontology: a Modular ApproachComment: in Adrian Paschke, Albert Burger, Andrea Splendiani, M. Scott Marshall, Paolo Romano: Proceedings of the 3rd International Workshop on Semantic Web Applications and Tools for the Life Sciences ...
Dmitrieva, Julia, Verbeek, Fons J.
core   +2 more sources

Short single-stranded DNA degradation products augment the activation of Toll-like receptor 9

Nature Communications, 2017
DNA degradation products are frequently found in the endosome, but how they regulate the activation of Toll-like receptors is not known. Here the authors show that single-stranded DNA as short as two nucleotides can enhance the ability of longer DNA ...
Jelka Pohar, Duško Lainšček, Karolina Ivičak-Kocjan, Miša-Mojca Cajnko, Roman Jerala, Mojca Benčina   +5 more
doaj   +1 more source

Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide [PDF]

, 2000
Egil Lien, Terry K. Means, Holger Heine, Atsutoshi Yoshimura, Shoichi Kusumoto, Koichi Fukase, Matthew J. Fenton, Masato Oikawa, Nilofer Qureshi, Brian G. Monks, Robert W. Finberg, Robin R. Ingalls, Douglas T. Golenbock   +12 more
openalex   +1 more source