Results 171 to 180 of about 618,091 (376)

Toll-Like Receptor Stimulation Enhances Phagocytosis and Intracellular Killing of Nonencapsulated and EncapsulatedStreptococcus pneumoniaeby Murine Microglia

open access: green, 2009
Sandra Ribes   +11 more
openalex   +1 more source

Targeted Enrichment of Engineered Bacteria on Triple‐Negative Breast Cancer Turns Immunologically Cold Tumors Hot

open access: yesAdvanced Science, EarlyView.
In this study, an “all‐in‐one” engineered anaerobic bacterial system (PDAEcN/COS) is developed for the treatment of immunologically “cold” TNBC. This nanoplatform is capable of colonizing tumor cell surfaces and implementing “self‐blocking” of immune checkpoints, while simultaneously suppressing tumor cells' “don't eat me” signals and delivering “eat ...
Xuanxiang Zhai   +6 more
wiley   +1 more source

TLR-9 Expression in Human Bronchial Epithelial Cells induced with Lipopolysaccharide [PDF]

open access: yes, 2010
The study conducted here was to investigate the gene and protein expression of Toll like receptor 9 when human bronchial epithelial cells were induced by lipopolysaccharide.
Sangeetha Dharmalingam   +1 more
core   +1 more source

Targeting the SOX9/TIMP1 Axis with iRGD‐Conjugated Nanoplatform Enhances Dendritic Cell Function and Photodynamic Immunotherapy in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
This study identifies the SOX9/TIMP1 axis as a key regulator of immune evasion in gastric cancer. iRGD‐conjugated nanoparticles co‐delivering si‐SOX9, Ce6, and L‐Arg are developed to synergize with photodynamic therapy. The nanoplatform suppresses tumor growth, promotes dendritic cell maturation, and enhances CD8+ T‐cell activation, offering a ...
Banghua Zhong   +3 more
wiley   +1 more source

Recognition of Commensal Microflora by Toll-Like Receptors Is Required for Intestinal Homeostasis

open access: yesCell, 2004
S. Rakoff-Nahoum   +4 more
semanticscholar   +1 more source

Single‐Cell Insights Into Macrophage Subtypes in Pulmonary Infections

open access: yesAdvanced Science, EarlyView.
This review highlights the dynamic plasticity of macrophages during pulmonary infections and proposes an integrative framework defining six functional subtypes: Inflam‐Ms, Hub‐Ms, Reg‐Ms, Prolif‐Ms, Memory‐Ms, and Senesc‐Ms. Single‐cell omics delineate their distinct roles in homeostasis and infection, refining our understanding of macrophage ...
Zhaoheng Lin   +3 more
wiley   +1 more source

Immune and Inflammatory Pathways in Non-Alcoholic Steatohepatitis (NASH). An update [PDF]

open access: yes, 2019
Non-alcoholic steatohepatitis (NASH), also known as fatty liver disease (FLD), is a major public health problem. It is considered to be the hepatic manifestation of the metabolic syndrome.
Breaban, Iulia   +10 more
core   +1 more source

Ionizable lipid nanoparticles of mRNA vaccines elicit NF-κB and IRF responses through toll-like receptor 4 [PDF]

open access: gold
Amanda E Zelkoski   +7 more
openalex   +1 more source

Toll-Like Receptor 3 Signal in Dendritic Cells Benefits Cancer Immunotherapy [PDF]

open access: gold, 2017
Misako Matsumoto   +3 more
openalex   +1 more source

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