Results 171 to 180 of about 310,367 (307)

Phylogenetic variation and polymorphism at the Toll-like receptor 4 locus (TLR4) [PDF]

, 2000
Irina Smirnova, Alexander Poltorak, Edward K. L. Chan, Colleen M. McBride, Bruce Beutler   +4 more
openalex   +1 more source

METTL3/ALKBH5‐Mediated N6‐Methyladenosine Modification Drives Macrophage M1 Polarization via the SLC15A3‐TASL‐IRF5 Signaling Axis in Psoriasis

Advanced Science, EarlyView.
m6A modification stabilizes Slc15a3 mRNA in macrophages, activating the SLC15A3‐TASL‐IRF5 axis and promoting psoriatic inflammation. Abstract Impaired N6‐methyladenosine (m6A) modification has been implicated in regulating various inflammatory diseases, but its role in psoriasis remains unclear.
Tao Huang, Shijun Chen, Ke Ding, Liyan Yuan, Weiqi Lv, Kechen Chen, Yuchen Liu, Dongzhao Ma, Xin Zhang, Xiaobo Wang, Guanzheng Luo, Bin Yang, Ying Lin, Zhili Rong   +13 more
wiley   +1 more source

The implication of dendritic cells in lung diseases: Immunological role of toll-like receptor 4

Genes and Diseases
The immune responses play a profound role in the progression of lung lesions in both infectious and non-infectious diseases. Dendritic cells, as the “frontline” immune cells responsible for antigen presentation, set up a bridge between innate and ...
Shurui Xuan, Yuan Ma, Honglei Zhou, Shengwei Gu, Xin Yao, Xiaoning Zeng   +5 more
doaj  

Toll-like receptors in mammalian sperm. [PDF]

Reprod Med Biol
Umehara T, Yamanaka T, Shimada M.
europepmc   +1 more source

Irisin‐Loaded Cerium‐Containing Mesoporous Bioactive Glass for Effective Immunomodulation and Odontogenesis of Dental Pulp Cells

Advanced Science, EarlyView.
The Irisin/Ce‐MBGNs delivery system can slowly release myokine Irisin for vital pulp therapy. Irisin/Ce‐MBGNs can enhance mitochondrial function and promote the differentiation of inflammatory macrophages toward M2‐Mφ, thereby regulating the immune response mechanism of inflamed dental pulp.
Mingxin Wang, Yuxin Yang, Jingyao Guo, Yan Chen, Xiaolin Lu, Guangdong Zhang, Yuli Wang, Minhui Yao, Yue Liu, Qian Ma   +9 more
wiley   +1 more source

Toll-Like Receptors in the Immunotherapy Era: Dual-Edged Swords of Tumor Immunity and Clinical Translation. [PDF]

MedComm (2020)
Maihemuti N, Shi Y, Zhang K, Jiang X, Chu J, Xu Y, Xu Z, Wang K.   +7 more
europepmc   +1 more source

Polymorphic Toll-like receptors [PDF]

, 2000
Ann‐Marie Mallon
openalex   +1 more source

Extracellular LCN2 Binding to 24p3R in Astrocytes Impedes α‐Synuclein Endocytosis in Parkinson's Disease

Advanced Science, EarlyView.
24p3R is an astrocytic receptor for α‐Syn uptake. When LCN2 is secreted from astrocytes, it binds to its receptor 24p3R in astrocytes and this binding impedes the α‐Syn PFF binding to 24p3R. This in turn inhibits 24p3R‐mediated α‐Syn PFF uptake and reduces the clearance of extracellular α‐Syn by astrocytes, which contributes to α‐Syn spread and ...
Ying‐Ying Jiao, Tian Tian, Zhu Zhu, Lei Cao, Yang Liu, Rui‐An Wang, Zhi‐Yong Zhou, Cong Wang, Ke‐Zhong Zhang, Xiao Lu, Wen‐Wei Yun, Ying‐Mei Lu, Gang Hu, Ren‐Hong Du, Ming Lu   +14 more
wiley   +1 more source

Role of toll-like receptors in post-COVID-19 associated neurodegenerative disorders? [PDF]

Front Med (Lausanne)
Satyanarayanan SK, Yip TF, Han Z, Zhu H, Qin D, Lee SMY.   +5 more
europepmc   +1 more source

Involvement of Toll-Like Receptor 4 in Innate Immunity to Respiratory Syncytial Virus [PDF]

, 2001
Lia M. Haynes, Deborah Moore, Evelyn A. Kurt‐Jones, Robert W. Finberg, Larry J. Anderson, Ralph A. Tripp   +5 more
openalex   +1 more source