Results 201 to 210 of about 310,367 (307)

Role of endosomal toll-like receptors in immune sensing of <i>Klebsiella pneumoniae</i>. [PDF]

Front Immunol
De Gaetano GV, Famà A, Lentini G, Coppolino F, Venza M, Venza I, Laganà P, Berbiglia A, Grasso F, Fiore L, Teti G, Beninati C.   +11 more
europepmc   +1 more source

USP45 Represses Melanoma Development by Deubiquitinating and Stabilizing Tumor Suppressor MRGPRF

Advanced Science, EarlyView.
USP45 acts as a melanoma suppressor by stabilizing MRGPRF, which weakens the PI3K/AKT pathway, suppresses tumor growth, and reduces melanoma cell migration and invasion. Abstract Melanoma, a highly malignant skin cancer, has seen a rising incidence and death toll. MRGPRF is a novel melanoma suppressor that inhibits the PI3K/AKT pathway.
Wancong Zhang, Liyun Chen, Jing Zhao, Aiwei Ma, Wenqi Shi, Yiwen Zhang, Zixuan Tang, Jiarui Guo, Zaihua Xu, Jianda Zhou, Shijie Tang   +10 more
wiley   +1 more source

Toll-like receptor family and signalling pathway [PDF]

, 2001
Marta Muzio, Nadia Polentarutti, Daniela Bosisio, Prakash P. Kumar, Alberto Mantovani   +4 more
openalex   +1 more source

Bidirectional Interaction Between the Brain and Bone in Traumatic Brain Injury

Advanced Science, EarlyView.
Traumatic brain injury (TBI) disrupts the blood–brain barrier and activates neuroimmune responses, causing metabolic disturbances and long‐term bone mass loss. Concurrent fractures accelerate healing and enhance osteogenesis but disrupt regulatory mechanisms, leading to altered bone dynamics and exacerbating neuroinflammation, complicating recovery ...
Wei Zhang, Jun Zou, Lingli Zhang
wiley   +1 more source

Functional toll-like receptors (TLR) are expressed on intestinal epithelial cells (IEC)

, 2000
Milena Bogunovic, Safak Reka, Kelly N. Evans, Lloyd Mayer, Kirk Sperber, Scott E. Plevy   +5 more
openalex   +1 more source

Escherichia coli P fimbriae utilize the Toll‐like receptor 4 pathway for cell activation [PDF]

, 2001
Björn Frendéus, Caroline Wachtler, Maria Hedlund, Hans Fischer, Patrik Samuelsson, Majlis Svensson, Catharina Svanborg   +6 more
openalex   +1 more source

Deciphering the Role and Mechanism of Decidual Monocyte‐Derived Macrophage Infiltration in Obstetric Antiphospholipid Syndrome at Single‐Cell Resolution

Advanced Science, EarlyView.
This study uncovers a novel mechanism and therapeutic targets in obstetric antiphospholipid syndrome (OAPS). Antiphospholipid antibody/ß2‐glycoprotein I complex boosts CCL2 and TNF‐α expression in decidual macrophages via TLR4‐NF‐κB. CCL2 accumulates on endothelial surfaces via ACKR1, recruiting monocyte‐derived CCR2+ macrophages, driving inflammation,
Rui Gao, Pingying Qing, Hanxiao Chen, Zhengyan Hu, Qiaoran Yang, Chenyang Lu, Huimin Liu, Rujun Zeng, Yuanting Tang, Fan Yu, Jinbiao Han, Xin Liao, Xun Zeng, Lang Qin   +13 more
wiley   +1 more source

Toll-like receptors in atopic dermatitis: pathogenesis and therapeutic implications. [PDF]

Heliyon
Vafaeian A, Rajabi F, Rezaei N.
europepmc   +1 more source

Induction of toll-like receptor 2 in human intestinal myofibroblasts by interferon gamma

, 2000
Martin Hausmann, Tanja Spoettl, Juergen Schöelmerich, Werner Falk, Tilo Andus, Gerhard Rogler   +5 more
openalex   +1 more source

Endocytosed HSP60s Use Toll-like Receptor 2 (TLR2) and TLR4 to Activate the Toll/Interleukin-1 Receptor Signaling Pathway in Innate Immune Cells [PDF]

, 2001
R. Martin Vabulas, Parviz Ahmad‐Nejad, Clarissa da Costa, Thomas Miethke, Carsten J. Kirschning, Hans Häcker, Hermann Wagner   +6 more
openalex   +1 more source