Results 231 to 240 of about 608,641 (362)

MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response

Proceedings of the National Academy of Sciences of the United States of America, 2012
M. Fabbri, A. Paone, F. Calore, R. Galli, E. Gaudio, R. Santhanam, F. Lovat, P. Fadda, C. Mao, G. Nuovo, N. Zanesi, Melissa Crawford, Gulcin H. Ozer, D. Wernicke, H. Alder, M. Caligiuri, P. Nana-Sinkam, D. Perrotti, C. Croce   +18 more
semanticscholar   +1 more source

Targeted Enrichment of Engineered Bacteria on Triple‐Negative Breast Cancer Turns Immunologically Cold Tumors Hot

Advanced Science, EarlyView.
In this study, an “all‐in‐one” engineered anaerobic bacterial system (PDAEcN/COS) is developed for the treatment of immunologically “cold” TNBC. This nanoplatform is capable of colonizing tumor cell surfaces and implementing “self‐blocking” of immune checkpoints, while simultaneously suppressing tumor cells' “don't eat me” signals and delivering “eat ...
Xuanxiang Zhai, Xiaoyi Shi, Xiao Liu, Xiaotong Gu, Wenting Li, Xiangjun Chen, Wei Hong   +6 more
wiley   +1 more source

RNA Viruses, Toll-Like Receptors, and Cytokines: The Perfect Storm? [PDF]

J Innate Immun
Stegeman SK, Kourko O, Amsden H, Pellizzari Delano IE, Mamatis JE, Roth M, Colpitts CC, Gee K.   +7 more
europepmc   +1 more source

Toll-Like Receptors Confer Responsiveness to Lipopolysaccharide fromPorphyromonas gingivalisin Human Gingival Fibroblasts

, 2000
Koichi Tabeta, Kazuhisa Yamazaki, Sachiko Akashi, Kensuke Miyake, Hidefumi Kumada, Toshio Umemoto, Hiromasa Yoshie   +6 more
openalex   +1 more source

Molecular Cloning and Functional Characterization of Chicken Toll-like Receptors [PDF]

, 2001
Aya Fukui, Naokazu Inoue, Misako Matsumoto, Midori Nomura, Kazuhiko Yamada, Yoichi Matsuda, Kumao Toyoshima, Tsukasa Seya   +7 more
openalex   +1 more source

Integrated Metabolic and Inflammatory Clustering Reveals Distinct Risk Profiles for Digestive Diseases

Advanced Science, EarlyView.
This study analyzes 398 432 participants, identifying four distinct metabolic‐inflammatory subtypes. These subtypes show a significant association with digestive disease risk. Cluster‐associated metabolite signatures partially explain this link. Machine learning models using these metabolites accurately predict risk for ten digestive diseases. Key risk
Zhenhe Jin, Qichen Chen, Liangfeng Zhou, Kexin Ye, Zhaoxue Liu, Wenxi Jiang, Linwen Luo, Yize Wang, Xiaohua Ye, Chaohui Yu, Zhe Shen   +10 more
wiley   +1 more source

Involvement of nucleic acid-sensing toll-like receptors in human diseases and their controlling mechanisms. [PDF]

J Biomed Sci
Lin YS, Chang YC, Pu TY, Chuang TH, Hsu LC.   +4 more
europepmc   +1 more source

Involvement of Toll-Like Receptor 4 in Innate Immunity to Respiratory Syncytial Virus [PDF]

, 2001
Lia M. Haynes, Deborah Moore, Evelyn A. Kurt‐Jones, Robert W. Finberg, Larry J. Anderson, Ralph A. Tripp   +5 more
openalex   +1 more source

Suppression of RNA recognition by Toll-like receptors: the impact of nucleoside modification and the evolutionary origin of RNA.

Immunity, 2005
K. Karikó, M. Buckstein, Houping Ni, D. Weissman   +3 more
semanticscholar   +1 more source

Lactate‐Modulating Nanoreactors Facilitate Self‐Amplifying Pyroptosis and the cGAS‐STING Cascade for Potentiated Catalytic‐Immunotherapy

Advanced Science, EarlyView.
An intelligent lactate‐depleting LOCoF2 (CoF2@LOx) nanoreactor system is developed to effectively induce self‐reinforced pyroptosis and activate the cGAS‐STING signaling pathway, thereby inducing a strong immune response and enhancing the therapeutic effectiveness of catalytic immunotherapy.
Linzhu Zhang, Shumin Sun, Duo Wang, Nailin Yang, Di Wang, Jihu Nie, Zifan Pei, Juan Qin, Lei Zhang, Haidong Zhu, Liang Cheng   +10 more
wiley   +1 more source