Results 261 to 270 of about 310,367 (307)

Role of Toll-like receptors in exosome biogenesis and angiogenesis capacity. [PDF]

Bioimpacts
Hassanpour P, Sadeghsoltani F, Safari MM, Haiaty S, Rahbarghazi R, Mota A, Rahmati M.   +6 more
europepmc   +1 more source

Anthocyanins Prevent Mastitis Exacerbation by Inhibiting PANoptosis Activation

Advanced Science, EarlyView.
PANoptosis activation is an effective therapeutic target during mastitis progression, and Gasdermin D activation is key factor contributing to blood milk barrier damage during mastitis, while cyanidin 3‐O‐galactoside can inhibit these targets to exert a protective effect. Therefore, the extraction of key active ingredients from plants for the treatment
Rui Feng, Lin Guo, Fan Wang, Qian Zhang, Guoyan Wang, Hefei Huang, Wei Du, Hong An, Yue Yang, Henghui Miao, Peng Zheng, Tingting Chu, Dengke Zhang, Xiaoxue Yan, Xiaoyu Mi, Qian Ma, Weilin Gao, Yushan Li, Song Li, Yong Zhang, Zhenliang Zhu, Yu Wang, Jun Liu, Xu Liu   +23 more
wiley   +1 more source

Toll-like Receptors: Key Players in Squamous Cell Carcinoma Progression. [PDF]

J Clin Med
Smok-Kalwat J, Mertowska P, Mertowski S, Góźdź S, Grywalska E.   +4 more
europepmc   +1 more source

Atrial Fibroblasts‐Derived Extracellular Vesicles Exacerbate Atrial Arrhythmogenesis

Advanced Science, EarlyView.
Exosome miR‐224‐5p derived from angiotensin II‐treated atrial fibroblasts creates a substrate for AF by promoting atrial electrical remodeling. Increased exosome miR‐224‐5p enhances AF susceptibility by inhibiting CACNA1c expression and decreasing ICa current of atrial cardiomyocytes.
Yue Yuan, Xinbo Zhao, Xuejie Han, Yukai Cao, Xuexin Jin, Ling Shi, Xin Bi, Desheng Li, Yun Zhang, Wenbo Ma, Jiahui Song, Zhenwei Pan, Zhiren Zhang, Yue Li   +13 more
wiley   +1 more source

Cyclophilin-CD147 interaction enables SARS-CoV-2 infection of human monocytes and their activation via Toll-like receptors 7 and 8. [PDF]

Front Immunol
Tajti G, Gebetsberger L, Pamlitschka G, Aigner-Radakovics K, Leitner J, Steinberger P, Stockinger H, Ohradanova-Repic A.   +7 more
europepmc   +1 more source

Cancer Cell‐Derived Large Extracellular Vesicles Promote Venous Thromboembolism by Activating NETosis Through Delivering CYBA

Advanced Science, EarlyView.
Venous thromboembolism (VTE) is a major threat to cancer patients. Cancer‐derived large extracellular vesicles deliver CYBA (p22phox) to neutrophils, triggering reactive oxygen species (ROS) and citrullinated histone H3 (citH3) formation. This drives neutrophil extracellular traps formation (NETosis), elevating VTE risk.
Xiangji Li, Yingjiao Ju, Chenjie Xu, Shixiang Ma, Lan Sun, Qingdong Guo, Mingyuan Liu, Yibin Xie, Li Min   +8 more
wiley   +1 more source

Innate immune sensors and regulators at the blood brain barrier: focus on toll-like receptors and inflammasomes as mediators of neuro-immune crosstalk and inflammation. [PDF]

J Neuroinflammation
Acioglu C, Elkabes S.
europepmc   +1 more source

Nature‐Inspired Nanostructures from Multiple‐Species Biomembranes: Rational Engineering and Therapeutic Applications in Tumor‐Targeted Nanomedicine

Advanced Science, EarlyView.
Naturally derived biomembrane nanostructures by mimicking evolutionarily optimized biological architectures could effectively suppress tumor growth and have emerged as a compelling strategy in translational biomedicine. This review provides a systematic overview of rational design and underlying antitumor therapeutic mechanisms of mammalian cells ...
Xiaodan Wei, Chi Wang, Xiangyan Chen, Yuanyuan Zhu, Mei Yang, Ningxi Li, Honglin Huang, Guangjian Zhang, Mingzhen Zhang, Yiyao Liu, Rui Gao   +10 more
wiley   +1 more source

Interactions between toll-like receptors signaling pathway and gut microbiota in host homeostasis. [PDF]

Immun Inflamm Dis
Chen L, Zhang L, Hua H, Liu L, Mao Y, Wang R.   +5 more
europepmc   +1 more source