Results 71 to 80 of about 618,091 (376)

Role of toll-like receptors and nod-like receptors in acute lung infection

open access: yesFrontiers in Immunology, 2023
The respiratory system exposed to microorganisms continuously, and the pathogenicity of these microbes not only contingent on their virulence factors, but also the host’s immunity. A multifaceted innate immune mechanism exists in the respiratory tract to
John Le   +3 more
doaj   +1 more source

Toll-like receptors in domestic animals [PDF]

open access: yes, 2018
Toll-like receptors are pattern recognition receptors with which hosts recognize pathogen-associated molecular patterns (PAMP). This recognition process is translated rapidly into a meaningful defense reaction.
Burgener, Iwan   +3 more
core  

Understanding diversity of human innate immunity receptors: analysis of surface features of leucine-rich repeat domains in NLRs and TLRs. [PDF]

open access: yes, 2009
BackgroundThe human innate immune system uses a system of extracellular Toll-like receptors (TLRs) and intracellular Nod-like receptors (NLRs) to match the appropriate level of immune response to the level of threat from the current environment.
Godzik, Adam, Istomin, Andrei Y
core   +4 more sources

The Role of Toll-like Receptor Agonists and Their Nanomedicines for Tumor Immunotherapy [PDF]

open access: gold, 2022
Lingling Huang   +4 more
openalex   +1 more source

Toll-Like Receptors in Skin [PDF]

open access: yesAdvances in Dermatology, 2008
TLRs have emerged as a major class of PRRs that are involved in detecting invading pathogens in the skin and initiating cutaneous immune responses. TLRs are expressed on many different cell types in the skin, including keratinocytes and Langerhans cells in the epidermis.
openaire   +2 more sources

Host‐Directed Biomaterials for Combatting Bloodstream Infections: From Macrocyclic Peptides to Immune‐Activating Cell Backpacks

open access: yesAdvanced Functional Materials, EarlyView.
Bloodstream infections (BSI) are one of the leading causes of mortality and morbidity in both civilian and military populations. This paper summarizes recent progress in novel treatment strategies to manage BSI arising from both bacterial and fungal pathogens using molecules, particles, and materials to elicit host‐directed immunity.
Thomas Thomou   +11 more
wiley   +1 more source

Modulation of pathogen recognition by autophagy

open access: yesFrontiers in Immunology, 2012
Autophagy is an ancient biological process for maintaining cellular homeostasis by degradation of long-lived cytosolic proteins and organelles. Recent studies demonstrated that autophagy is availed by immune cells to regulate innate immunity.
Ji Eun eOh, Heung Kyu eLee
doaj   +1 more source

Expression of Toll-like receptors in nasal epithelium in allergic rhinitis [PDF]

open access: yes, 2015
Toll-like receptors (TLRs) are important in barrier homeostasis, but their role in airborne allergies is not fully understood. The aim was to evaluate baseline and allergen-induced expression of TLR proteins in nasal epithelium during allergic rhinitis ...
Haglund, Caj   +8 more
core   +1 more source

TIRAP, TRAM, and Toll-Like Receptors: The Untold Story [PDF]

open access: gold, 2023
Valérie Lannoy   +3 more
openalex   +1 more source

Membrane Vesicles from Lacticaseibacillus Casei BL23 Exhibit Antimicrobial Activity Against Escherichia coli and Immunostimulatory Effects on Human Peripheral Blood Mononuclear Cells

open access: yesAdvanced Healthcare Materials, EarlyView.
Membrane vesicles derived from the probiotic Lacticaseibacillus casei BL23 demonstrate antimicrobial properties against Escherichia coli and a potential biological effect in improving the overall survival of C. elegans infected with Pseudomonas aeruginosa. These vesicles stimulated immune responses in primary cells without causing toxicity. Our results
Cecilia L. D'Antoni   +11 more
wiley   +1 more source

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