Results 51 to 60 of about 7,136,272 (253)

Mechanisms of firing patterns in fast-spiking cortical interneurons. [PDF]

PLoS Computational Biology, 2007
Cortical fast-spiking (FS) interneurons display highly variable electrophysiological properties. Their spike responses to step currents occur almost immediately following the step onset or after a substantial delay, during which subthreshold oscillations
David Golomb, Karnit Donner, Liron Shacham, Dan Shlosberg, Yael Amitai, David Hansel   +5 more
doaj   +1 more source

GGA3KO mice display deficits in GABAergic tonic current.

, 2016
Recordings were made from DGGCs in hippocampal slices from 6–8 week-old GGA3WT and GGA3KO mice in the presence of 1μM GABA. Tonic current was determined by measuring the difference in holding current amplitude before and after applying 100 μM picrotoxin (
Selene Lomoio (2794003), David Albrecht (2794009), Kendall R. Walker (2794000), Amit Modgil (502187), Philip G. Haydon (506299), Stephen J. Moss (2794006), Giuseppina Tesco (189424)   +6 more
core   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Astrocytic α4 Subunit-Containing GABAA Receptors are Critical for Etomidate-Induced Sustained Increase in Tonic Current in Neurons [PDF]

, 2023
Etomidate triggers a sustained increase in tonic current in neurons that is associated with persistent cognitive deficits. Astrocytic GABAA receptors (GABAAR) are necessary for this effect as they release secreted factors.
Ju, Li
core   +1 more source

Rupture of Urinary Bladder: A Sequelae of Tonic-clonic Seizure Complications [PDF]

, 2021
Seizures are capable of causing different types of physical injuries ranging from superficial contusions up to severe head injuries or even bone fractures.
Fatima Aldoseri, Ahmet Aslan, Yasser Abdelrahman, Erdem Yılmaz, Wael Ibrahim   +4 more
core   +1 more source

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani, Emmanuel Barbeau, Béatrice Lemesle, Emilie Milongo‐Rigal, Sophie Fernandez, Sandrine Charpentier, Jean‐François Albucher, Nicolas Raposo, Fabrice Bonneville, Patrice Péran, Jérémie Pariente   +10 more
wiley   +1 more source

Tonic Pupil Following Traumatic Hyphema: Case Report

, 2013
A 7-year-old girl was admitted to our clinic after crash injury with air gun pellet in her right eye. There was an intense anterior chamber reaction and hyphema on the biomicroscopic examination. During the control examination after treatment of hyphema
Şansal Gedik, Bengü Ekinci Köktekir, Berker Bakbak, Şaban Gönül, Abdullah Beyoğlu   +4 more
core   +1 more source

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig, Nadav Amir, Maya Schiller, Roni Loebenstein, Johnatan Nissan, Marina Boxer, Shany Guly Gofrit, Gal Goshen, Sándor Beniczky, Nicola Maggio   +9 more
wiley   +1 more source

Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova, Jan Smeitink, Herma Renkema, Rosabeth White, Frankie Barton, Rachel Lyon, Jane Newman, Aye Moe, Yi Shiau Ng, Grainne Siobhan Gorman   +9 more
wiley   +1 more source

Tonic immobility in two species of Southern African catsharks

, 2020
Magister Scientiae (Biodiversity and Conservation Biology) - MSc (Biodiv and Cons Biol)Tonic immobility (TI) can be defined as an unlearned behavioural response described by a physical state of immobility. This behaviour can last from a few seconds up to
Sebastian, Lemόne Margeaux
core