Results 21 to 30 of about 209,354 (197)

Human Skin Aging and the Anti-Aging Properties of Retinol

Biomolecules, 2023
The skin is the most-extensive and -abundant tissue in the human body. Like many organs, as we age, human skin experiences gradual atrophy in both the epidermis and dermis.
Taihao Quan
doaj   +1 more source

Acne: current perspective

Journal of Applied Pharmaceutical Research, 2017
Acne vulgaris or acne is a multi factorial chronic inflammatory disease of pilosebaceous unit. Globally it affects approximately 9.4% of the population. It is characterized by blackheads and white heads, pinheads, large papules which may lead to scarring.
Manju Kamra, Anupama Diwan
doaj   +1 more source

Response of papillon–Lefevre syndrome to acitretin

Indian Journal of Paediatric Dermatology, 2021
Papillon–Lefevre (PLS) is a rare autosomal recessive disorder of keratinization characterized by symmetric, trans-gradient type palmoplantar keratoderma (PPK), rapidly progressive periodontopathy, and precocious loss of dentition.
Priyanka Arun Kowe, P Lavanya, Vaishali H Wankhade, Rajesh P Singh   +3 more
doaj   +1 more source

Confluent and Reticulated Papillomatosis Successfully Treated with Topical Vitamin A Derivative

Case Reports in Dermatological Medicine, 2023
Confluent and reticulated papillomatosis (CARP) is a rare dermatosis that typically develops in adolescents and young adults. Clinical characteristics include hyperkeratotic papules that coalesce centrally with a reticulated pattern peripherally on the ...
Manal Alsulami, Bader Alharbi, Yaser Alotaibi, Fadi Alghamdi, Adel Alsantali   +4 more
doaj   +1 more source

Comparative Study Between Tacrolimus 0.1% Ointment Versus Topical White Soft Petrolatum Jelly in the Treatment of Oral Retinoid-Induced Cheilitis

Indian Journal of Dermatology
Retinoids are used topically as well as orally, and the most commonly used oral retinoids are isotretinoin and acitretin. Mucocutaneous adverse effects are frequently seen with the use of systemic retinoids, the most common being cheilitis, which is dose-
Rohit Kothari, Devayani Pol, Divya Asnani, Shreya Deoghare, Ajay Kumar, Yash Buccha   +5 more
doaj   +1 more source

A Rare De Novo Missense Mutation in IFT122 Confers a Genetic Susceptibility Factor of Idiopathic Pediatric Uveitis Via Trio‐based Whole‐Exome Sequencing

Advanced Science, EarlyView.
A rare de novo IFT122‐A773E variant is identified in idiopathic pediatric uveitis and shown to exacerbate retinal inflammation and barrier dysfunction. Mechanistically, the variant enhances IFT43 interaction, elevates calcium signaling, and activates the MEK/ERK/FRA1 axis, revealing a previously unrecognized cilia‐associated pathway that may increase ...
Qian Zhou, Jiaxing Huang, Yilin Wang, Xingran Li, Xianyang Liu, Lingyu Dai, Hongshun Li, Qingfeng Wang, Jiangyi Liu, Guannan Su, Wanyun Zhang, Yang Deng, Qingfeng Cao, Yujie Lai, Xiang Luo, Changwei Huang, Ling Chen, Shengping Hou, Peizeng Yang   +18 more
wiley   +1 more source

When meta‐analyses mislead: Promises and pitfalls in teratology counselling

British Journal of Clinical Pharmacology, EarlyView.
Meta‐analysis has become a central tool for evidence synthesis in clinical teratology, offering the promise of increased statistical power, earlier signal detection and consolidated guidance for teratology counselling. When conducted rigorously and interpreted carefully, pooled analyses can provide clinicians with a structured basis for risk ...
Yusuf Cem Kaplan, Nusret Uysal
wiley   +1 more source

Topical antibacterials in dermatology

Indian Journal of Dermatology, 2021
Topical antibacterials are commonly used for superficial pyodermas such as impetigo and treatment or prevention of infections following minor cuts, abrasions, burns, and surgical wounds.
Debabrata Bandyopadhyay
doaj   +1 more source

Transparent Surfactant‐Based Isotropic Systems for Topical Co‐Delivery of Hydrophilic and Lipophilic Actives for Striae Distensae

Journal of Surfactants and Detergents, EarlyView.
ABSTRACT Striae distensae are common dermal lesions that negatively affect skin appearance, and topical management remains limited by challenges related to skin deposition and residence time. Here, we developed transparent surfactant‐based isotropic systems for the topical co‐delivery of ascorbic acid (AA), retinoic acid (RA), and lavender essential ...
Claudiane Ayres Prochno, Anna Paula Brusamarello, Anna Cláudia Morais de Oliveira Capote, Thais Leticia Moreira da Silva, Gabriela Ruva Fagundes, Giovani Marino Favero, Marina Tolentino Marinho, Benjamim Melo de Carvalho, Priscileila Colerato Ferrari   +8 more
wiley   +1 more source

Topical retinoids in oral lichen planus treatment: an overview

, 2013
Treatment of oral lichen planus (OLP) is a major challenge for clinicians and patients. There is limited scientific evidence about topical treatment with retinoids.
Lajolo C, Lajolo, Carlo, Campus G, C. Lajolo, Petruzzi M, G. Campus, R. Serpico, PETRUZZI, MASSIMO, D. Lauritano, SERPICO, Rosario, Lauritano D, LUCCHESE, Alberta, A. Lucchese, LUCCHESE A, SERPICO R   +14 more
core   +1 more source