Results 1 to 10 of about 310 (103)

Heterologous Production of Torularhodin, the Monocyclic Carotenoid with a Terminal Carboxyl Group, in <i>Escherichia coli</i>. [PDF]

BioTech (Basel)
Torularhodin is the monocyclic C40 carotenoid with the β-ring and a terminal carboxyl group at the acyclic part, with long conjugated double bonds, only synthesized in fungi called red (oleaginous) yeasts, e.g., the genera Rhodotorula and Sporobolomyces.
Takemura M, Maoka T, Misawa N.
europepmc   +3 more sources

The carotenoid torularhodin alleviates NAFLD by promoting Akkermanisa muniniphila-mediated adenosylcobalamin metabolism. [PDF]

Nat Commun
Nature Communications, 16 (1)
Liu C, Zheng X, Ji J, Zhu X, Liu X, Liu H, Guo L, Ye K, Zhang S, Xu YJ, Sun X, Zhou W, Wong HLX, Tian Y, Qian H.   +14 more
europepmc   +5 more sources

Study on the Cellular Anti-Inflammatory Effect of Torularhodin Produced by Sporidiobolus pararoseus ZQHL Isolated from Vinegar Fungus. [PDF]

Molecules, 2023
The red stretcher bacterium Sporidiobolus pararoseus is a high producer of carotenoids such as torularhodin, but its presence in vinegar has not been detected. Moreover, torularhodin has several biological activities, but its effect on the LPS-induced RAW 264.7 inflammatory cell model has also yet to be elucidated. In this study, S.
Liu C, Han M, Lv F, Gao Y, Wang X, Zhang X, Guo Y, Cheng Y, Qian H.   +8 more
europepmc   +4 more sources

A Novel <i>Rhodotorula evergladensis</i> CXCN-6 Rich in Torularhodin and PUFAs with Potent Antioxidant and Anti-Inflammatory Activities. [PDF]

Antioxidants (Basel)
Carotenoids and microbial lipids are valuable bioactive compounds with potent antioxidant and anti-inflammatory properties. Microbial biosynthesis provides a sustainable alternative to conventional plant extraction and chemical synthesis. Here, we report the isolation and characterization of a novel oleaginous yeast, Rhodotorula evergladensis CXCN-6 ...
Park C, Park M, Li T, Shen C, Zheng Z, Ge Y, Jin X, Wei M, Choi J, Hwang JS, Li Z.   +10 more
europepmc   +3 more sources

Determination of the Molecular Mechanism of Torularhodin against Hepatic Oxidative Damage by Transcriptome Analysis. [PDF]

Oxid Med Cell Longev, 2019
Torularhodin, extracted from Sporidiobolus pararoseus, is a significant carotenoid that is similar to lycopene in structure. Some studies have indicated torularhodin as having antioxidative activities. However, it has not been thoroughly studied with respect to its antioxidative activity and molecular mechanisms in liver injury.
Li J, Guo Y, Cheng Y, Pi F, Yao W, Xie Y, Qian H.   +6 more
europepmc   +4 more sources

A New Method for Selective Extraction of Torularhodin from Red Yeast Using CO₂-SFE Technique. [PDF]

Appl Biochem Biotechnol
AbstractTorularhodin is a dark pink colored carotenoid belonging to the xanthophylls group that can be biologically synthesized by red yeasts, especially by Rhodotorula and Sporobolomyces genera. The growing interest in this molecule is due to its biological activities such as antioxidant, anticholesterolemic, anti-inflammatory, antimicrobial, and ...
Ambrico A, Larocca V, Trupo M, Martino M, Magarelli RA, Spagnoletta A, Balducchi R.   +6 more
europepmc   +4 more sources

Strategies for Recovery, Purification and Quantification of Torularhodin Produced by Rhodotorula mucilaginosa Using Different Carbon Sources

Fermentation, 2023
Torularhodin is a fungus-derived carotenoid, and the lack of downstream processing of torularhodin is still a challenge for its large-scale production. To support the industrial production of torularhodin, this work initially evaluated the efficiency of carotenoid release from Rhodotorula mucilaginosa using thermal acid treatment, saponification and ...
Junjie Yi, Zhijia Liu, Yi Junjie
exaly   +3 more sources

Torularhodin Alleviates Hepatic Dyslipidemia and Inflammations in High-Fat Diet-Induced Obese Mice via PPARα Signaling Pathway [PDF]

Molecules, 2022
Genyi Zhang, Yuliang Cheng, He Qian
exaly   +2 more sources

Aspects of the stereochemistry of torularhodin biosynthesis [PDF]

Biochemical Journal, 1970
1. The incorporation of [2-14C]acetate, [2-14C]mevalonic acid and [2-14C,2-3H2]-mevalonic acid into torulene and torularhodin by Rhodotorula rubra and Rhodotorula glutinis was studied. 2. A recovery of 14.3% of the label was obtained on decarboxylation of the torularhodin biosynthesized from [2-14C]mevalonic acid. 3.
R E, Tefft, T W, Goodwin, K L, Simpson
openaire   +2 more sources

Torulene and torularhodin: “new” fungal carotenoids for industry? [PDF]

Microbial Cell Factories, 2018
Torulene and torularhodin represent the group of carotenoids and are synthesized by yeasts and fungi. The most important producers of these two compounds include yeasts of Rhodotorula and Sporobolomyces genera. The first reports confirming the presence of torulene and torularhodin in the cells of microorganisms date to the 1930s and 1940s; however ...
Anna Kot, Stanisław Błażejak, Iwona Gientka, Marek Kieliszek, Joanna Bryś   +4 more
openaire   +4 more sources