Results 91 to 100 of about 9,569,482 (202)

Gentiopicroside Regulates EGFR and Induces Its Lysosomal Degradation to Attenuate Heart Failure

open access: yesPhytotherapy Research, EarlyView.
GPS attenuates pressure overload‐induced cardiac remodeling by promoting lysosomal degradation of EGFR. TAC‐induced EGFR accumulation activates AKT/ERK1/2 signaling and drives pathological cardiac hypertrophy, fibrosis, apoptosis, oxidative stress, and cardiac dysfunction. GPS promotes lysosome‐dependent EGFR degradation, thereby limiting excessive AKT/
Mingzhen Cao   +6 more
wiley   +1 more source

Chemiluminescent determination of total antioxidant capacity during winemaking

open access: yes, 2006
The total antioxidant capacity (TAC) of five different wines (four red and one white) was determined in five different steps of winemaking carried out in a commercial wine cellar by a chemiluminescent (CL) assay.
L. Bolelli   +15 more
core   +1 more source

Natural Polysaccharides for Rheumatoid Arthritis Therapy: Mechanism, Drug Delivery and Clinical Application

open access: yesPhytotherapy Research, EarlyView.
Schematic overview of the experimental models, therapeutic mechanisms, drug delivery systems, and clinical potential of natural polysaccharides in rheumatoid arthritis. ABSTRACT Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized primarily by chronic synovitis.
Luxin Li   +14 more
wiley   +1 more source

Butein Attenuates Cardiac Hypertrophy by Restoring Redox–Mitochondrial Homeostasis Through Nrf2–Sirt3 Signaling

open access: yesPhytotherapy Research, EarlyView.
Butein attenuates pathological cardiac hypertrophy by activating Nrf2–Sirt3 signaling, restoring mitochondrial function and redox homeostasis. ABSTRACT Butein (3,4,2′,4′‐tetrahydroxychalcone) is a bioactive chalcone with antioxidant, anti‐inflammatory, and cytoprotective properties.
Tsendsuren Tungalag, Dong Kwon Yang
wiley   +1 more source

Relationship between DNA damage and total antioxidant capacity in patients with transitional meningioma

open access: yes, 2007
Purpose: The purpose of this study was to assess oxidative DNA damage and total antioxidant capacity (TAC) in patients with transitional meningioma (TM) and to compare the results with normal brain ...
Kacira, Tibet   +8 more
core   +1 more source

Developmental stage is an important factor that determines the antioxidant responses of young and old grapevine leaves under UV irradiation in a green-house. [PDF]

open access: yes, 2012
The impact of UV irradiation was studied on photosynthesis, photosystem II photochemical yields and antioxidant responses using green-house grown grapevine (Vitis vinifera L. cv. Chardonnay) leaves.
Éva Hideg   +3 more
core   +2 more sources

Comparison of different tests used in mapping the Greek virgin olive oil production for the determination of its total antioxidant capacity

open access: yesGrasas y Aceites, 2010
This study aims to map the total antioxidant capacity (TAC) of 50 Greek olive oil samples from the 2005-2006 season according to production region and cultivar and to compare the 2, 2’-azino-bis (3-ethylbenzo-thiazoline-6- sulfonic acid (ABTS), 2, 2 ...
Katerina S. Minioti   +1 more
doaj   +1 more source

Tumor microenvironment responsive and nanozyme‐catalyzed photodynamic therapy via lysosome‐localized copper‐doped carbon dots

open access: yesResponsive Materials, EarlyView.
The lysosome‐localized copper‐doped carbon dots (Cu‐MLCDs) leverage the high expression of glutathione (GSH)/H2O2 in the tumor microenvironment to achieve fluorescence reactivation enhancement. Through its multi‐nanozyme activities (glutathione peroxidase, peroxidase, and catalase), this nanoplatform relieves hypoxia, depletes GSH, and synergistically ...
Weixia Qin   +8 more
wiley   +1 more source

Sialic acid associated with oxidative stress and total antioxidant capacity (TAC) expression level as a predictive indicator in moderate to severe Alzheimer's disease

open access: yesExperimental Gerontology, 2020
Several studies have shown many risk factors associated with disease onset, but the sialic acid association with oxidative stress biomarkers may a key factor in the pathogenesis of Alzheimer's disease (AD). We aim to find out the most specific biomarker from the peripheral blood samples in moderate to severe Alzheimer's patients.This study examined the
Jyoti, Yadav   +6 more
openaire   +2 more sources

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