Results 131 to 140 of about 14,498,613 (385)

Synthesis of the Sex Pheromone of the Tea Tussock Moth Based on a Resource Chemistry Strategy

open access: yesMolecules, 2018
Synthesis of the sex pheromone of the tea tussock moth in 33% overall yield over 10 steps was achieved. Moreover, the chiral pool concept was applied in the asymmetric synthesis.
Hong-Li Zhang   +5 more
doaj   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

open access: yesMolecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé   +7 more
wiley   +1 more source

Synthetic avenues towards a tetrasaccharide related to Streptococcus pneumonia of serotype 6A

open access: yesBeilstein Journal of Organic Chemistry, 2018
Streptococcus pneumonia (SPn) is a Gram-positive bacterium which causes life threatening diseases. The bacteria protect themselves against non-specific host defence by an external polysaccharide (PS) capsule which bears a repeating unit, α-D-Galp(1->3)-α-
Aritra Chaudhury   +2 more
doaj   +1 more source

Design and Synthesis of a Novel Ganglioside Ligand for Influenza A Viruses <sup>†</sup>

open access: yesMolecules, 2012
A novel ganglioside bearing Neua2-3Gal and Neua2-6Gal structures as distal sequences was designed as a ligand for influenza A viruses. The efficient synthesis of the designed ganglioside was accomplished by employing the cassette coupling approach as a ...
Tomohiro Nohara   +8 more
doaj   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

Recent Advances in the Stereoselective Total Synthesis of Natural Pyranones Having Long Side Chains

open access: yesMolecules, 2020
Pyranone natural products have attracted great attention in recent years from chemists and biologists due to their fascinating stereoisomeric structural features and impressive bioactivities.
Satya Kumar Avula   +4 more
doaj   +1 more source

Convergent and Biomimetic Enantioselective Total Synthesis of (-)-Communesin F.

open access: yesJournal of the American Chemical Society, 2016
The first biomimetic enantioselective total synthesis of (-)-communesin F based on a late-stage heterodimerization and aminal exchange is described. Our synthesis features the expedient diazene-directed assembly of two advanced fragments to secure the ...
S. Lathrop   +3 more
semanticscholar   +1 more source

Catalytic Asymmetric Total Synthesis of (-)-Actinophyllic Acid.

open access: yesJournal of the American Chemical Society, 2016
Described herein is a catalytic asymmetric total synthesis of (-)-actinophyllic acid, with the key step being a chiral phosphine-catalyzed [3 + 2] annulation between an imine and an allenoate to form a pyrroline intermediate in 99% yield and 94% ee.
Lingchao Cai, Kui Zhang, O. Kwon
semanticscholar   +1 more source

Fischer indole synthesis applied to the total synthesis of natural products

open access: yes, 2017
One of the oldest and most useful reactions in organic chemistry is the Fischer indole synthesis (FIS). It is known to have a wide variety of applications including the synthesis of indole rings, often present as the framework in the total synthesis of ...
M. Heravi   +3 more
semanticscholar   +1 more source

Total Synthesis of Lycopalhine A

open access: yesSynthesis, 2016
The total synthesis of lycopalhine A featuring the construction of a tricyclic system via cleavage of a cyclopropane ring and an ensuing intramolecular Michael addition, stereoselective introduction of a 2-aminoethyl moiety via a reaction of ...
Yuji Ochi, S. Yokoshima, T. Fukuyama
semanticscholar   +1 more source

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