Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
First Divergent Total Synthesis of (±)-Nobilin D and Structurally Related Bibenzyl Natural Products. [PDF]
Sreenivas K, Nageswara Rao C.
europepmc +1 more source
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
Total synthesis of natural products based on hydrogenation of aromatic rings. [PDF]
Wu H, Qi X.
europepmc +1 more source
First total synthesis of (±)-spirobroussonin B via electromediated oxidative coupling for constructing spirodienone ring. [PDF]
Shi HJ +6 more
europepmc +1 more source
Advances in Zr-mediated radical transformations and applications to total synthesis. [PDF]
Ogawa H, Nakamura H.
europepmc +1 more source
Total Synthesis of the SJG-2 Glycan: General Strategies for Constructing Sterically Congested Sialylated Glycans. [PDF]
Su YY +6 more
europepmc +1 more source
Total Synthesis of Antimalarial Macrolide Strasseriolide A by Ni/Zr-Mediated Reductive Ketone Coupling. [PDF]
Umehara A, Kawakita KH, Sasaki M.
europepmc +1 more source
Unified Total Synthesis of Phrymarolin and Haedoxan Natural Products. [PDF]
Paciorek J +4 more
europepmc +1 more source
Related searches:
Total synthesis of (−)-raumacline
Chem. Commun., 2003AbstractFor Abstract see ChemInform Abstract in Full Text.
Bailey, Patrick D. +4 more
openaire +2 more sources

