Results 111 to 120 of about 55,159 (299)
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Zjawisko totalitaryzmu w perspektywie dzieła Hannah Arendt [PDF]
, 2011 The following article is an attempt to analyze Arendt's reflections on the roots of totalitarianism. The focus is on the biographical context which underlines her intellectual and spiritual progress as a Jewish person.
Kula, Luiza
core
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The last flight of F/O Tadeusz Stabrowski. Identification of the polish pilot. [PDF]
Front Genet, 2023 Lisman D +10 more
europepmc +1 more source
The Law of Political Economy: An Introduction [PDF]
, 2020 The law of political economy is a contentious ideological field characterised by antagonistic relations between scholarly positions which tend to be either affirmative or critical of capitalism. Going beyond this schism, two particular features appear as
Kjaer, Poul F.
core
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Wildlife markets, COVID-19 and totalitarianism: A comment on Cawthorn et al. [PDF]
Ambio, 2021 Orenstein RI.
europepmc +1 more source
Pleasures in Socialism: Leisure and Luxury in the Eastern Bloc [PDF]
, 2010 This book is a significant contribution to the studies of everyday life in Eastern Europe under communist rule. It is the third in a series of volumes edited and written with Susan E.
Crowley, David, Reid, Susan Emily
core
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source