Results 121 to 130 of about 55,159 (299)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Gaos, intérprete de la modernidad como totalitarismo / Gaos interpreter of the crisis of Modernity as Totalitarianism

open access: yesBajo Palabra, 2017
Este artículo investiga, especialmente en los materiales inéditos del archivo de Gaos, la noción de totalitarismo como diagnóstico de su época. Gaos considera que a la modernización como proceso de laicización, tecnificación y degradación del sujeto y ...
Sergio Sevilla Segura
doaj  

'A Balance of Power that Favors Freedom'. The Historical and Ideological Roots of the Neo-Conservative Persuasion [PDF]

open access: yes
The paper offers a genealogy of neoconservatism, concentrating on its ideological and historical foundations in the early 1970s. In the first part, it shows how neoconservatism represented a reaction to the crisis-real and perceived-the United States was
Mario del Pero
core  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Luis Goytisolo’s \u3cem\u3eLa paradoja del ave migratoria\u3c/em\u3e as Postmodern Allegory: A Critique of Absolutism [PDF]

open access: yes, 2000
Luis Goytisolo’s short work of fiction, La paradoja del ave migratoria, was published in 1987 in a Post-Franco Spain and a Postmodern world. I will investigate this unusual novel as a postmodern allegory, relying on Brian McHale’s assertion that ...
Carney, Terri
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Narrative and Belonging: The Politics of Ambiguity, The Jewish State, and the Thought of Edward Said and Hannah Arendt [PDF]

open access: yes, 2017
At the core of this thesis, I examine the difficulties of giving an account of oneself in modern associational life. By integrating the theory and political activism of both Edward Said and Hannah Arendt, I follow the Zionist response to European ...
Bessen, Jacob, Bessen, Jacob A
core   +1 more source

Home - About - Disclaimer - Privacy