Results 101 to 110 of about 18,233,686 (171)

ORF43/ORF44: a possible Toxin-Antitoxin system in phiCh1

, 2016
Eine Sequenzanalyse des Genoms von phiCh1 zeigte eine Pin Domäne im ORF44 auf, ein Hinweis auf ein Typ II Toxin/Antitoxin System. In dieser Bachelorarbeit wurden die Auswirkungen von ORF43/44, einem möglichem Toxin/Antitoxin System im Virus phiCh1 ...
Lebhard, Jürgen
core   +1 more source

Higher-Order Structure in Bacterial VapBC Toxin-Antitoxin Complexes

, 2017
Toxin-antitoxin systems are widespread in the bacterial kingdom, including in pathogenic species, where they allow rapid adaptation to changing environmental conditions through selective inhibition of key cellular processes, such as DNA replication or ...
Brodersen, Ditlev E, Ditlev E. Brodersen, Bendtsen, Kirstine L, Kirstine L. Bendtsen   +3 more
core   +1 more source

Novel type II toxin-antitoxin systems with VapD-like proteins

mBio
Type II toxin-antitoxin (TA) systems are widespread in prokaryotes. They consist of neighboring genes encoding two small proteins: a toxin that inhibits a critical cellular process and an antitoxin that binds to and neutralizes the toxin.
Konstantin Gilep, Dmitry Bikmetov, Aleksandr Popov, Anastasiia Rusanova, Shunsuke Tagami, Svetlana Dubiley, Konstantin Severinov   +6 more
doaj   +1 more source

The role of a toxin-antitoxin system in the arms race between bacteria and phage

, 2023
All domains of life face the fundamental challenge of responding to infection by pathogens. In bacteria, the need to survive predation by phages, or bacterial viruses, has driven the evolution of numerous highly sophisticated anti-phage elements ...
Guegler, Chantal Katrin
core  

Kinetic simulations of selected toxin-antitoxin modules

Moduli toksin-antitoksin so manjši genetski sistemi, ki so množično prisotni v genomih bakterij in arhej. Najpogosteje zaporedje vsebuje zapis za proteina toksin in antitoksin, ter operatorsko regijo, preko katere se uravnava nivo izražanja obeh ...
Urbič, Zala
core  

Toxin-Antitoxin Battle in Bacteria

, 2013
This PhD thesis consists of three research projects revolving around the common thread of investigation of the properties and biological functions of Toxin-Antitoxin loci.
Cataudella, Ilaria
core   +1 more source

Structural and functional characterization of VapBC52 toxin-antitoxin system from Mycobacterium tuberculosis. [PDF]

Nucleic Acids Res
Singh M, Singh C, Nair AV, Ahmad I, Sharma A, Bhasin M, Jain V, Singh R, Thakur KG.   +8 more
europepmc   +1 more source

Central role of vapBC toxin-antitoxin system expression in the pathogenicity and antimicrobial resistance of Shigella sonnei isolates from pediatric diarrheal patients. [PDF]

BMC Infect Dis
Pagheh G, Alikhani MY, Karami P, Shalchi Z, Mohammadi Y, Taheri M.   +5 more
europepmc   +1 more source

Ribosomal RNA cleavage by the previously unidentified RelS-RelI toxin-antitoxin system controls growth of Mycobacterium tuberculosis. [PDF]

Nucleic Acids Res
Han X, Arrowsmith TJ, Karamycheva S, Xu X, Coddeville M, Pagès C, Voisin B, Gutierrez C, Neyrolles O, Makarova KS, Blower TR, Genevaux P.   +11 more
europepmc   +1 more source

A haloarchaeal VapBC toxin-antitoxin system: regulatory mechanism and role in establishing population heterogeneity to facilitate survival of subpopulations under stress conditions. [PDF]

Appl Environ Microbiol
He D, Lin Y, Zhang Y, Liu Y, Li P, Su X, Qu X, Liu Y, Shao X, Wen H, Luo H, Wu Y, Gan F, Tang X-F, Tang B.   +14 more
europepmc   +1 more source