Results 101 to 110 of about 28,780 (174)

Type II Toxin-Antitoxin Systems in Escherichia coli

He Zhang,1 Shuan Tao,2 Huimin Chen,2 Yewei Fang,2 Yao Xu,3 A-Xiang Han,2 Fang Ma,1,* Wei Liang2,* 1Department of Medical Laboratory, Bengbu Medical University, Bengbu, Anhui, People’s Republic of China; 2Department of Clinical Laboratory, The ...
Fang Y, Han AX, Liang W, Zhang H, Tao S, Chen H, Ma F, Xu Y   +7 more
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Automated discovery and phylogenetic analysis of new toxin-antitoxin systems.

, 2008
Although often viewed as elements "at the service of" bacteria, plasmids exhibit replication and maintenance mechanisms that make them purely "selfish DNA" candidates.
Michel C Milinkovitch, Guglielmini, Julien, Szpirer, Cédric, Cedric Y Szpirer, Guglielmini Julien, Milinkovitch, Michel, Szpirer Cédric, Milinkovitch Michel C, Julien Guglielmini   +8 more
core   +1 more source

Novel type II toxin-antitoxin systems with VapD-like proteins

mBio
Type II toxin-antitoxin (TA) systems are widespread in prokaryotes. They consist of neighboring genes encoding two small proteins: a toxin that inhibits a critical cellular process and an antitoxin that binds to and neutralizes the toxin.
Konstantin Gilep, Dmitry Bikmetov, Aleksandr Popov, Anastasiia Rusanova, Shunsuke Tagami, Svetlana Dubiley, Konstantin Severinov   +6 more
doaj   +1 more source

Type II toxin: antitoxin systems. More than small selfish entities?

, 2016
Toxin-antitoxin (TA) modules regulate metabolism and viability of bacteria and archaea. In type II TA systems these functions are generally thought to be performed by two small proteins.
Rocker, A., Meinhart, A.
core   +1 more source

A competence-regulated toxin-antitoxin system in Haemophilus influenzae

, 2018
Natural competence allows bacteria to respond to environmental and nutritional cues by taking up free DNA from their surroundings, thus gaining nutrients and genetic information.
Rosemary J. Redfield, Rachel L. Ehrlich, Joshua Chang Mell, Scott Mastromatteo, Sunita Sinha, Corey Nislow, Hailey Findlay Black   +6 more
core   +1 more source

Regulation of toxin-antitoxin systems by proteolysis.

, 2013
Toxin-antitoxin systems are widely distributed among many bacterial species, including human pathogens. Regulation of type II TA system functions, where both components are proteins, relies on proteolysis.
Brzozowska, Iwona, Zielenkiewicz, Urszula   +1 more
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Toxin-antitoxin Systems: Classification, Biological Function and Application in Biotechnology

, 2014
The toxin-antitoxin (TA) systems are systems in which an unstable antitoxin inhibits a stable toxin. This review aims to introduce the TA system and its biological application in bacteria.
Raftari, M., Sekawi, Z., Sadeghifard, N., Ghafourian, S.   +3 more
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Phages carry orphan antitoxin-like enzymes to neutralize the DarTG1 toxin-antitoxin defense system

The astounding number of anti-phage defenses encoded by bacteria is countered by an elaborate set of phage counter-defenses, though their evolutionary origins are often unknown. Here, we report the discovery of an orphan antitoxin counter-defense element
Johannesman, Anna, Carlson, Nico, Awasthi, Leila C, LeRoux, Michele   +3 more
core   +1 more source

Toxin antitoxin system as an antimicrobial target for antibiotic resistant staphylococcus aureus [PDF]

, 2014
Antibiotic-resistant bacteria have become a global concern and new strategies to control pathogenic bacteria are urgently needed. Toxin antitoxin (TA) system is defined as a regulator system consist of toxin that neutralized by cognate antitoxin.
Ghafouryan, Sobhan
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Kinetic simulations of selected toxin-antitoxin modules

Moduli toksin-antitoksin so manjši genetski sistemi, ki so množično prisotni v genomih bakterij in arhej. Najpogosteje zaporedje vsebuje zapis za proteina toksin in antitoksin, ter operatorsko regijo, preko katere se uravnava nivo izražanja obeh ...
Urbič, Zala
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