Geometric Properties of Isostables and Basins of Attraction of Monotone Systems [PDF]
, 2017 In this paper, we study geometric properties of basins of attraction of monotone systems. Our results are based on a combination of monotone systems theory and spectral operator theory.
Mauroy, Alexandre, Sootla, Aivar
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Biopharmaceuticals for Cancer Treatment: An Update
Cancer Medicine, Volume 15, Issue 4, April 2026.ABSTRACT Cancer is one of the most debilitating diseases, causing profound physical and psychological impacts on patients. The global number of cancer patients has been steadily rising over the last few decades. The development of effective cancer therapies remains the primary focus in life science research, requiring a precise understanding of ...
Anupom Deb Nath +6 more
wiley +1 more source
Identification and characterisation of toxin-antitoxin systems (TA) in Burkholderia pseudomallei [PDF]
, 2013 The aim of this study was to identify and characterise type II toxin-antitoxin (TA) systems in Burkholderia pseudomallei, the causative agent of the human disease melioidosis. 8 putative TA systems were identified within the genome of B. pseudomallei
Butt, Aaron Trevor
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Transcriptional cross-activation between toxin-antitoxin systems of Escherichia coli [PDF]
, 2013 BACKGROUND: Bacterial toxin-antitoxin (TA) systems are formed by potent regulatory or suicide factors (toxins) and their short-lived inhibitors (antitoxins). Antitoxins are DNA-binding proteins and auto-repress transcription of TA operons.
Niilo Kaldalu +3 more
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Cassette recombination dynamics within chromosomal integrons are regulated by toxin–antitoxin systems [PDF]
, 2022 Egill Richard +16 more
openalex +1 more source
Insecticide@Silica Nanocontainers with High Cypermethrin Load and Improved Photostability
ChemNanoMat, Volume 12, Issue 4, April 2026.Cypermethrin@Octylsilicate core@shell nanocontainers (total diameter: 34 nm, diameter of cypermethrin core: 15 nm) exhibit high colloidal stability in water and high photochemical stability of the insecticide, allowing to reduce reapplication cycles and, thus, time and costs of insecticide application.
Mark Rutschmann +2 more
wiley +1 more source
Phylogenetic identification of bacterial MazF toxin protein motifs among probiotic strains and foodborne pathogens and potential implications of engineered probiotic intervention in food [PDF]
, 2012 BACKGROUND: Toxin-antitoxin (TA) systems are commonly found in bacteria and Archaea, and it is the most common mechanism involved in bacterial programmed cell death or apoptosis. Recently, MazF, the toxin component of the toxin-antitoxin module, has been
Jing Hu +4 more
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mLife, Volume 5, Issue 2, Page 180-198, April 2026.Abstract Bacterial persisters show tolerance to bactericidal antibiotics and play essential roles in chronic infections; however, the general mechanisms underlying persister formation and antibiotic tolerance remain insufficiently characterized. In this study, the Escherichia coli Keio library was used to identify genes involved in ciprofloxacin ...
Zhenfang Mei +9 more
wiley +1 more source
Bistability in type I toxin-antitoxin systems may lead to stress-induced persister formation
npj Systems Biology and ApplicationsAntibiotic persistence, characterized by a dormant subpopulation of bacterial cells that causes chronic and recurrent infections, remains poorly understood despite being recognized nearly a century ago. Toxin–antitoxin (TA) systems, which include a toxin
Sofija Markovic +3 more
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Evolution of the SpoIISABC Toxin-Antitoxin-Antitoxin System in Bacilli
Toxins, 2016 Programmed cell death in bacteria is generally associated with two-component toxin-antitoxin systems. The SpoIISABC system, originally identified in Bacillus subtilis, consists of three components: a SpoIISA toxin and the SpoIISB and SpoIISC antitoxins ...
Marek Gabriško, Imrich Barák
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