Results 81 to 90 of about 28,780 (174)
Bistability in type I toxin-antitoxin systems may lead to stress-induced persister formation
npj Systems Biology and ApplicationsAntibiotic persistence, characterized by a dormant subpopulation of bacterial cells that causes chronic and recurrent infections, remains poorly understood despite being recognized nearly a century ago. Toxin–antitoxin (TA) systems, which include a toxin
Sofija Markovic +3 more
doaj +1 more source
, 2018 Bakterije su razvile iznimnu sposobnost prilagodbe na različite životne uvjete. Uz pomoć raznih sustava i mehanizama daju brz stanični odgovor na stresore, tretman antibiotikom, stanje gladi i ostale nepovoljne uvjete. Jedan takav sustav pronađen je u
Matković, Katarina
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Higher-Order Structure in Bacterial VapBC Toxin-Antitoxin Complexes
, 2017 Toxin-antitoxin systems are widespread in the bacterial kingdom, including in pathogenic species, where they allow rapid adaptation to changing environmental conditions through selective inhibition of key cellular processes, such as DNA replication or ...
Brodersen, Ditlev E +3 more
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PLoS ONE, 2012 Bacterial toxin-antitoxin (TA) systems encode two proteins, a potent inhibitor of cell proliferation (toxin) and its specific antidote (antitoxin). Structural data has revealed striking similarities between the two model TA toxins CcdB, a DNA gyrase ...
Andrew B Smith +8 more
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Time to Diagnosis and Persistence: The Two Major Determinants of Effective Tuberculosis Control
, 2015 The greatest challenge confronting effective tuberculosis (TB) eradication is the time to diagnosis, and duration of treatment of chronically infected individuals which represent a pool of infection.
Ruthe, Alaine Tess
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conformational changes of antitoxin HigA by binding of toxin HigB
, 2021 학위논문(박사)--아주대학교 일반대학원 :분자과학기술학과,2021. 2General Introduction 1 Shigella flexneri 1 Persistent cells and toxin-antitoxin system 2 Multidrug resistance and multidrug tolerance 5 Six types of toxin-antitoxin system 7 Conditional cooperativity 10 Chapter
윤원수
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Type II toxin/antitoxin system genes expression in persister cells of Klebsiella pneumoniae
, 2020 Objective: Persistence is a subpopulation of bacteria that can tolerate high doses of antibiotics by undergoing a period of dormancy. This study aimed to investigate the hypothetical role of toxin/antitoxin systems in persister cell formation of ...
Razavi, S. +13 more
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The Biology and Biochemistry of PhoH2 proteins
, 2013 PhoH2 proteins are found in a diverse range of organisms. To date little is known about these proteins and the role they play in the organisms in which they reside.
Andrews, Emma Sophie Vout
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, 2011 Toxin-antitoxin systems are prevalent in different bacterial organisms and are encoded in the chromosomal or plasmid DNA. The primary function of a plasmid toxin-antitoxin module is to stabilize the plasmid by eliminating plasmid-free daughter cells ...
Patil, Rocky
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, 2023 International audienceThe bacterial toxin–antitoxin systems are each composed of a toxin, which severely inhibits bacterial cells growth, and a specific neutralizing antitoxin.
Duperray, Maëlle +2 more
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