Results 81 to 90 of about 18,233,686 (171)
ABSTRACT Anthocyanins are plant derived biomolecules that play roles in pollination and protection against ultraviolet light (UV) radiation, as well as reactive oxygen and nitrogen species (ROS and RNS, respectively). Cyanidin 3‐O‐glucoside (C3G), a common anthocyanin in the diet, exhibits antioxidant capacity that depends on its chemical structure ...
Eiko Osawa‐Martínez +6 more
wiley +1 more source
Keeping the wolves at bay: antitoxins of prokaryotic type II toxin-antitoxin systems
In their initial stages of discovery, prokaryotic toxin-antitoxin (TA) systems were confined to bacterial plasmids where they function to mediate the maintenance and stability of usually low- to medium-copy number plasmids through the post-segregational ...
Wai Ting eChan +2 more
doaj +1 more source
Asking the 5 W's for designing next‐generation bioprocessing
Abstract Biotechnology is expanding beyond traditional, centralized fermentation and toward next‐generation bioprocessing paradigms that emphasize flexible deployment outside the laboratory with application‐specific performance. However, many bioprocesses fail to translate beyond proof‐of‐concept into industrially viable systems because early design ...
Sangdo Yook +4 more
wiley +1 more source
Type II Toxin-Antitoxin Systems in Escherichia coli [PDF]
He Zhang,1 Shuan Tao,2 Huimin Chen,2 Yewei Fang,2 Yao Xu,3 A-Xiang Han,2 Fang Ma,1,* Wei Liang2,* 1Department of Medical Laboratory, Bengbu Medical University, Bengbu, Anhui, People’s Republic of China; 2Department of Clinical Laboratory, The ...
Fang Y +7 more
core
Polyphenol assembly chemistry provides a versatile basis for antibacterial biomaterials. Matching material format and function to the distinct barriers of wound, respiratory, intestinal, and implant‐associated infections is central to effective and translatable design. ABSTRACT Bacterial infections involving multidrug‐resistant pathogens and persistent
Wei Yang +4 more
wiley +1 more source
Antitoxin autoregulation of M. tuberculosis toxin-antitoxin expression through negative cooperativity arising from multiple inverted repeat sequences [PDF]
Toxin-antitoxin systems play key roles in bacterial adaptation, including protection from antibiotic assault and infection by bacteriophages. The type IV toxin-antitoxin system AbiE encodes a DUF1814 nucleotidyltransferase-like toxin, and a two-domain ...
Blower, T.R. +4 more
core +1 more source
Time to Diagnosis and Persistence: The Two Major Determinants of Effective Tuberculosis Control [PDF]
The greatest challenge confronting effective tuberculosis (TB) eradication is the time to diagnosis, and duration of treatment of chronically infected individuals which represent a pool of infection.
Ruthe, Alaine Tess
core
Biology and evolution of bacterial toxin–antitoxin systems
Toxin–antitoxin systems are widespread in bacterial genomes. They are usually composed of two elements: a toxin that inhibits an essential cellular process and an antitoxin that counteracts its cognate toxin.
Fraikin, Nathan +7 more
core +1 more source
Bistability in type I toxin-antitoxin systems may lead to stress-induced persister formation
Antibiotic persistence, characterized by a dormant subpopulation of bacterial cells that causes chronic and recurrent infections, remains poorly understood despite being recognized nearly a century ago. Toxin–antitoxin (TA) systems, which include a toxin
Sofija Markovic +3 more
doaj +1 more source
Evolution of the SpoIISABC Toxin-Antitoxin-Antitoxin System in Bacilli
Programmed cell death in bacteria is generally associated with two-component toxin-antitoxin systems. The SpoIISABC system, originally identified in Bacillus subtilis, consists of three components: a SpoIISA toxin and the SpoIISB and SpoIISC antitoxins ...
Marek Gabriško, Imrich Barák
doaj +1 more source

