Results 61 to 70 of about 18,233,686 (171)

Investigation of activity of acinetobacter baumannii toxin-antitoxin system antitoxin. [PDF]

, 2016
Investigation of Activity of Acinetobacter baumannii Toxin-antitoxin System Antitoxin Acinetobacter baumannii is a gram negative opportunistic pathogen which causes variety of nosocomial infections.
Čepauskas, Albinas,
core  

prlF and yhaV encode a new toxin-antitoxin system in Escherichia coli

, 2007
Toxin-antitoxin systems consist of a stable toxin, frequently with endonuclease activity, and a small, labile antitoxin, which sequesters the toxin into an inactive complex.
Lupas, A. ; https://orcid.org/, Djuranovic, S., Schuenemann, V., Schmidt, O., Silhavy, T., Hand, N., Martin, J. ; https://orcid.org/   +6 more
core   +1 more source

Regulation of toxin-antitoxin systems by proteolysis. [PDF]

, 2013
Toxin-antitoxin systems are widely distributed among many bacterial species, including human pathogens. Regulation of type II TA system functions, where both components are proteins, relies on proteolysis.
Brzozowska, Iwona, Zielenkiewicz, Urszula   +1 more
core   +1 more source

Charting the Voyages of Acinetobacter baumannii in Southeast Asia: Mapping the Regional Genomic Landscape

MicrobiologyOpen, Volume 15, Issue 6, December 2026.
A genomic analysis of 853 Southeast Asian Acinetobacter baumannii isolates reveals the regional dominance of the highly resistant Global Clone 2 (GC2) lineage. Characterised by diverse mobile elements and distinct phage defenses, these findings establish a critical baseline to guide future surveillance and broader regional sampling.
Soo Sum Lean, Prasit Palittapongarnpim, Stuart C. Clarke, Chew Chieng Yeo   +3 more
wiley   +1 more source

Characterization of the interaction and cross-regulation of three Mycobacterium tuberculosis RelBE modules. [PDF]

PLoS ONE, 2010
RelBE represents a typical bacterial toxin-antitoxin (TA) system. Mycobacterium tuberculosis H37Rv, the pathogen responsible for human tuberculosis, contains three RelBE-like modules, RelBE, RelFG, and RelJK, which are at least partly expressed in human ...
Min Yang, Chunhui Gao, Yi Wang, Hua Zhang, Zheng-Guo He   +4 more
doaj   +1 more source

Metabolomics‐based study of the preservation mechanism of a tea saponin–cinnamaldehyde nanoemulsion applied to Xinyu tangerines

Journal of the Science of Food and Agriculture, Volume 106, Issue 14, Page 8467-8480, November 2026.
Abstract Background The Xinyu tangerine is a geographical indication agricultural product from Jiangxi province, China. During postharvest storage, nutrient loss and pathogen‐induced decay reduce fruit quality. The selection of appropriate preservatives is therefore important for maintaining postharvest quality.
Yan Leng, Xinjian Gao, Yichen Zhang, Zehang Yan, Wanyi Chen, Yang Huang, Xiaoxia Zuo, Liqin Zhu, Zhipeng Cai, Jing Wang, Yonggen Shen   +10 more
wiley   +1 more source

The VapBC-4 Characterization Indicates It Is a Bona Fide Toxin-Antitoxin Module of Leptospira interrogans: Initial Evidence for a Role in Bacterial Adaptation

Microorganisms
Toxin-antitoxin (TA) systems are one of the bacterial adaptation mechanisms to adverse conditions. Leptospira interrogans serovar Copenhageni contains nine putative TA systems.
Bruna Oliveira Pigatto Azevedo, Deborah Kohn Damiano, Aline Florencio Teixeira, Ana Lucia Tabet Oller Nascimento, Luis Guilherme Virgilio Fernandes, Alexandre Paulo Yague Lopes   +5 more
doaj   +1 more source

Integrative Modeling in the Age of Machine Learning: A Summary of HADDOCK Strategies in CAPRI Rounds 47–55

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 11, Page 1746-1752, November 2026.
ABSTRACT The HADDOCK team participated in CAPRI rounds 47–55 as server, manual predictor, and scorers. Throughout these CAPRI rounds, we used a plethora of computational strategies to predict the structure of protein complexes. Of the 10 targets comprising 24 interfaces, we achieved acceptable or better models for 3 targets in the human category and 1 ...
Victor Reys, Marco Giulini, Vlad Cojocaru, Anna Engel, Xiaotong Xu, Jorge Roel‐Touris, Cunliang Geng, Francesco Ambrosetti, Brian Jiménez‐García, Zuzana Jandova, Panagiotis I. Koukos, Charlotte van Noort, João M. C. Teixeira, Siri C. van Keulen, Manon Réau, Rodrigo V. Honorato, Alexandre M. J. J. Bonvin   +16 more
wiley   +1 more source

Chaperone addiction of toxin–antitoxin systems

, 2016
International audienceBacterial toxin–antitoxin (TA) systems, in which a labile antitoxin binds and inhibits the toxin, can promote adaptation and persistence by modulating bacterial growth in response to stress.
Bordes, Patricia, Slama, Nawel, Genevaux, Pierre, Sala, Ambre Julie, Cirinesi, Anne-Marie, Guillet, Valérie, Mourey, Lionel, Ayala, Sara, Texier, Pauline   +8 more
core   +1 more source

Excitable dynamics through toxin-induced mRNA cleavage in bacteria.

PLoS ONE, 2019
Toxin-antitoxin (TA) systems in bacteria and archaea are small genetic elements consisting of the genes coding for an intracellular toxin and an antitoxin that can neutralize this toxin. In various cases, the toxins cleave the mRNA.
Stefan Vet, Alexandra Vandervelde, Lendert Gelens   +2 more
doaj   +1 more source