Results 11 to 20 of about 424 (50)
Microorganisms, 2021 Agrobacterium tumefaciens is a pathogen of various plants which transfers its own DNA (T-DNA) to the host plants. It is used for producing genetically modified plants with this ability.
Wonho Choi +9 more
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BMC Genomics, 2006 Background Post-segregational killing systems are present in a large variety of microorganisms. When found on plasmids, they are described as addiction systems that act to maintain the plasmid during the partitioning of the cell.
Mahillon Jacques, Fico Sarah
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Frontiers in Microbiology, 2021 The extraordinary expansion of Toxin Antitoxin (TA) modules in the genome of Mycobacterium tuberculosis has received significant attention over the last few decades.
Arun Sharma +10 more
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Dynamics-Based Regulatory Switches of Type II Antitoxins: Insights into New Antimicrobial Discovery
Antibiotics, 2023 Type II toxin-antitoxin (TA) modules are prevalent in prokaryotes and are involved in cell maintenance and survival under harsh environmental conditions, including nutrient deficiency, antibiotic treatment, and human immune responses. Typically, the type
Ki-Young Lee, Bong-Jin Lee
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Charged Amino Acids Contribute to ZorO Toxicity
Toxins, 2022 Chromosomally encoded toxin-antitoxin systems have been increasingly identified and characterized across bacterial species over the past two decades. Overproduction of the toxin gene results in cell growth stasis or death for the producing cell, but co ...
Bikash Bogati +4 more
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Expression, Purification, and Functional Analysis of Novel RelE Operon from X. nematophila
The Scientific World Journal, 2014 Bacterial toxin-antitoxin (TA) complexes induce programmed cell death and also function to relieve cell from stress by various response mechanisms. Escherichia coli RelB-RelE TA complex consists of a RelE toxin functionally counteracted by RelB antitoxin.
Jitendra Singh Rathore +1 more
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PLoS Genetics, 2020 RHS elements are components of conserved toxin-delivery systems, wide-spread within the bacterial kingdom and some of the most positively selected genes known. However, very little is known about how Rhs toxins affect bacterial biology.
Magnus Stårsta +8 more
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Evaluating the Potential for Cross-Interactions of Antitoxins in Type II TA Systems
Toxins, 2020 The diversity of Type-II toxin–antitoxin (TA) systems in bacterial genomes requires tightly controlled interaction specificity to ensure protection of the cell, and potentially to limit cross-talk between toxin–antitoxin pairs of the same family of TA ...
Chih-Han Tu +3 more
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Toxin-Antitoxin Systems as Multilevel Interaction Systems
Toxins, 2014 Toxin-antitoxin (TA) systems are small genetic modules usually composed of a toxin and an antitoxin counteracting the activity of the toxic protein. These systems are widely spread in bacterial and archaeal genomes.
Nathalie Goeders, Laurence Van Melderen
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Applications of toxin-antitoxin systems in synthetic biology
Engineering Microbiology, 2023 Toxin-antitoxin (TA) systems are ubiquitous in bacteria and archaea. Most are composed of two neighboring genetic elements, a stable toxin capable of inhibiting crucial cellular processes, including replication, transcription, translation, cell division ...
Jianzhong Lin +4 more
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