Results 111 to 120 of about 16,346 (193)

Characterization of Chromosomally Encoded Toxin-Antitoxin Systems in Streptococcus pyogenes [PDF]

, 2019
Streptococcus pyogenes ist ein humanpathogenes Bakterium, welches verschiedene Gewebe besiedeln kann und dadurch unterschiedliche Krankheiten verursacht.
Zarate Bonilla, Lina Johana, Bonilla, Lina Johana   +1 more
core   +1 more source

Viral evasion of a bacterial suicide system by RNA-based molecular mimicry enables infectious altruism.

PLoS Genetics, 2012
Abortive infection, during which an infected bacterial cell commits altruistic suicide to destroy the replicating bacteriophage and protect the clonal population, can be mediated by toxin-antitoxin systems such as the Type III protein-RNA toxin-antitoxin
Tim R Blower, Terry J Evans, Rita Przybilski, Peter C Fineran, George P C Salmond   +4 more
doaj   +1 more source

Automated discovery and phylogenetic analysis of new toxin-antitoxin systems.

, 2008
Although often viewed as elements "at the service of" bacteria, plasmids exhibit replication and maintenance mechanisms that make them purely "selfish DNA" candidates.
Michel C Milinkovitch, Guglielmini, Julien, Szpirer, Cédric, Cedric Y Szpirer, Guglielmini Julien, Milinkovitch, Michel, Szpirer Cédric, Milinkovitch Michel C, Julien Guglielmini   +8 more
core   +1 more source

Type II toxin: antitoxin systems. More than small selfish entities?

, 2016
Toxin-antitoxin (TA) modules regulate metabolism and viability of bacteria and archaea. In type II TA systems these functions are generally thought to be performed by two small proteins.
Rocker, A., Meinhart, A.
core   +1 more source

Toxin Inactivation in Toxin/Antitoxin Systems

, 2019
Toxin/antitoxin (TA) systems are used primarily to inhibit phage, reduce metabolic activity during stress, and maintain genetic elements. Given the extreme toxicity of some of the toxins of these TA systems, we were curious how the cell silences toxins, if the antitoxin is inactivated or when toxins are obtained without antitoxins via horizontal gene ...
Laura Fernandez-Garcia, Jun-Seob Kim, Maria Tomas, Thomas K. Wood   +3 more
openaire   +2 more sources

Toxin-antitoxin Systems: Classification, Biological Function and Application in Biotechnology

, 2014
The toxin-antitoxin (TA) systems are systems in which an unstable antitoxin inhibits a stable toxin. This review aims to introduce the TA system and its biological application in bacteria.
Raftari, M., Sekawi, Z., Sadeghifard, N., Ghafourian, S.   +3 more
core  

A simple BLASTn-based approach generates novel insights into the regulation and biological function of type I toxin-antitoxins

mSystems
Bacterial chromosomal type I toxin-antitoxin systems consist of a small protein, typically under 60 amino acids, and a small RNA (sRNA) that represses toxin translation.
Selene F. H. Shore, Michael Ptacek, Andrew D. Steen, Elizabeth M. Fozo   +3 more
doaj   +1 more source

Excitable dynamics through toxin-induced mRNA cleavage in bacteria.

PLoS ONE, 2019
Toxin-antitoxin (TA) systems in bacteria and archaea are small genetic elements consisting of the genes coding for an intracellular toxin and an antitoxin that can neutralize this toxin. In various cases, the toxins cleave the mRNA.
Stefan Vet, Alexandra Vandervelde, Lendert Gelens   +2 more
doaj   +1 more source

Proteic toxin-antitoxin, bacterial plasmid addiction systems and their evolution with special reference to the pas system of pTF-FC2

, 1999
Genes encoding toxin-antitoxin proteins are frequently found on plasmids where they serve to stabilize the plasmid within a bacterial population. The toxin-antitoxin proteins do not increase the likelihood of a progeny cell receiving a plasmid but rather
Rawlings D.E.
core   +1 more source

Type II Toxin-Antitoxin Systems in Escherichia coli

He Zhang,1 Shuan Tao,2 Huimin Chen,2 Yewei Fang,2 Yao Xu,3 A-Xiang Han,2 Fang Ma,1,* Wei Liang2,* 1Department of Medical Laboratory, Bengbu Medical University, Bengbu, Anhui, People’s Republic of China; 2Department of Clinical Laboratory, The ...
Fang Y, Han AX, Liang W, Zhang H, Tao S, Chen H, Ma F, Xu Y   +7 more
core