Results 121 to 130 of about 9,494,692 (194)

Toxin Inactivation in Toxin/Antitoxin Systems

, 2019
Toxin/antitoxin (TA) systems are used primarily to inhibit phage, reduce metabolic activity during stress, and maintain genetic elements. Given the extreme toxicity of some of the toxins of these TA systems, we were curious how the cell silences toxins, if the antitoxin is inactivated or when toxins are obtained without antitoxins via horizontal gene ...
Laura Fernandez-Garcia, Jun-Seob Kim, Maria Tomas, Thomas K. Wood   +3 more
openaire   +2 more sources

Investigation of activity of acinetobacter baumannii toxin-antitoxin system antitoxin. [PDF]

, 2016
Investigation of Activity of Acinetobacter baumannii Toxin-antitoxin System Antitoxin Acinetobacter baumannii is a gram negative opportunistic pathogen which causes variety of nosocomial infections.
Čepauskas, Albinas,
core  

Structural and functional diversity of toxin-antitoxin-chaperone systems

Summary: Toxin-antitoxin-chaperone (TAC) systems are three-part gene clusters encoding a toxin, antitoxin, and specialized SecB-like chaperone (SecBTA) with emerging roles in phage defense.
Tenson, Tanel, Mets, Toomas, Gemma C. Atkinson, Vasili Hauryliuk, Tanel Tenson, Odai, Roni, Kurata, Tatsuaki, Jose A. Nakamoto, Nakamoto, Jose A, Roni Odai, Atkinson, Gemma C, Toomas Mets, Tatsuaki Kurata, Hauryliuk, Vasili, Hauryliuk, Vasili,, Tenson, Tanel,, Nakamoto, Jose A,, Kurata, Tatsuaki,, Odai, Roni,, Lund University., Mets, Toomas,, Atkinson, Gemma C,   +21 more
core   +1 more source

Higher-Order Structure in Bacterial VapBC Toxin-Antitoxin Complexes

, 2017
Toxin-antitoxin systems are widespread in the bacterial kingdom, including in pathogenic species, where they allow rapid adaptation to changing environmental conditions through selective inhibition of key cellular processes, such as DNA replication or ...
Brodersen, Ditlev E, Ditlev E. Brodersen, Bendtsen, Kirstine L, Kirstine L. Bendtsen   +3 more
core   +1 more source

Understanding the physiological role and cross-interaction network of VapBC35 toxin-antitoxin system from Mycobacterium tuberculosis

Communications Biology
The VapBC toxin-antitoxin (TA) system, composed of VapC toxin and VapB antitoxin, has gained attention due to its relative abundance in members of the M. tuberculosis complex.
Neelam Singh, Gopinath Chattopadhyay, Niranjana Sri Sundaramoorthy, Raghavan Varadarajan, Ramandeep Singh   +4 more
doaj   +1 more source

Microcystis aeruginosa msoT1/msoA1 Locus Displays Features of a Type I Toxin–Antitoxin System

Toxins
Type I toxin–antitoxin (TA) systems consist of a protein toxin that exerts a cytostatic or cytotoxic effect and an antisense RNA antitoxin that prevents translation of the toxin.
Matija Ruparčič, Marko Dolinar
doaj   +1 more source

Toxin-antitoxin systems in bacteria : mechanisms, targets and specificity

, 2015
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Biology, 2015.Title as it appears in MIT Commencement Exercises program, June, 2015: Toxin-antitoxin systems in bacteria : targets, mechanisms, and specificity.
Aakre, Christopher David
core  

Acquisition and erosion of toxin-antitoxin systems in bacterial chromosomes. [PDF]

Mol Biol Evol
Belot L, Payelleville A, Jurėnas D, Rocha EPC, Van Melderen L.   +4 more
europepmc   +1 more source

The role of toxin-antitoxin systems in <i>Helicobacter pylori</i> adaptability. [PDF]

J Bacteriol
Romero-Carpio JD, Chacón-Loría LD, Molina-Castro S, Mendoza-Guido B.   +3 more
europepmc   +1 more source

Bacterial Toxin-Antitoxin Systems' Cross-Interactions-Implications for Practical Use in Medicine and Biotechnology. [PDF]

Toxins (Basel), 2023
Boss L, Kędzierska B.
europepmc   +1 more source