Results 121 to 130 of about 16,346 (193)

Toxin-antitoxin systems in bacteria : mechanisms, targets and specificity

, 2015
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Biology, 2015.Title as it appears in MIT Commencement Exercises program, June, 2015: Toxin-antitoxin systems in bacteria : targets, mechanisms, and specificity.
Aakre, Christopher David
core  

Understanding the physiological role and cross-interaction network of VapBC35 toxin-antitoxin system from Mycobacterium tuberculosis

Communications Biology
The VapBC toxin-antitoxin (TA) system, composed of VapC toxin and VapB antitoxin, has gained attention due to its relative abundance in members of the M. tuberculosis complex.
Neelam Singh, Gopinath Chattopadhyay, Niranjana Sri Sundaramoorthy, Raghavan Varadarajan, Ramandeep Singh   +4 more
doaj   +1 more source

Microcystis aeruginosa msoT1/msoA1 Locus Displays Features of a Type I Toxin–Antitoxin System

Toxins
Type I toxin–antitoxin (TA) systems consist of a protein toxin that exerts a cytostatic or cytotoxic effect and an antisense RNA antitoxin that prevents translation of the toxin.
Matija Ruparčič, Marko Dolinar
doaj   +1 more source

Bacterial toxin-antitoxin systems targeting translation

, 2010
10 p.-2 fig.Toxin-antitoxin systems (TAS) emerged more than 25 years ago and have since developed as an important field in molecular microbiology. TAS are autoregulated operons coding a stable toxin and an unstable antitoxin found in the plasmids and ...
Ramón Díaz-Orejas, Concha Nieto, Nieto, Concha, López-Villarejo, Juan, Lemonnier, Marc, Hernández-Arriaga, A.M., Inma Moreno-Córdoba, Ana María Hernández Arriaga, Espinosa, Manuel, Marc Lemonnier, Moreno-Córdoba, Inmaculada, Manuel Espinosa, Díaz-Orejas, Ramón, Elizabeth Diago-Navarro, Diago-Navarro, Elizabeth, Juan López-Villarejo   +15 more
core   +1 more source

Proteolytic Regulation of Toxin-Antitoxin Systems by ClpPC in Staphylococcus aureus

, 2009
Bacterial toxin-antitoxin (TA) systems typically consist of a small, labile antitoxin that inactivates a specific longer-lived toxin. In Escherichia coli, such antitoxins are proteolytically regulated by the ATP-dependent proteases Lon and ClpP.
Donegan, Niles P, Cheung, Ambrose L, Thompson, Earl T, Fu, Zhibiao   +3 more
core   +1 more source

Higher-Order Structure in Bacterial VapBC Toxin-Antitoxin Complexes

, 2017
Toxin-antitoxin systems are widespread in the bacterial kingdom, including in pathogenic species, where they allow rapid adaptation to changing environmental conditions through selective inhibition of key cellular processes, such as DNA replication or ...
Brodersen, Ditlev E, Ditlev E. Brodersen, Bendtsen, Kirstine L, Kirstine L. Bendtsen   +3 more
core   +1 more source

Specificity Determinants of Homologous VapBC Toxin-Antitoxin Systems

, 2020
Thesis (Ph.D.)--University of Rochester. School of Medicine & Dentistry. Dept. of Microbiology and Immunology, 2018.Type II toxin-antitoxin (TA) systems are ubiquitous in bacteria and archaea, where they play a pivotal role in the establishment and ...
Walling, Lauren R., Butler, J. Scott
core  

Investigation of activity of acinetobacter baumannii toxin-antitoxin system antitoxin.

, 2016
Investigation of Activity of Acinetobacter baumannii Toxin-antitoxin System Antitoxin Acinetobacter baumannii is a gram negative opportunistic pathogen which causes variety of nosocomial infections.
Čepauskas, Albinas,
core  

Bacterial Toxin-Antitoxin Systems' Cross-Interactions-Implications for Practical Use in Medicine and Biotechnology. [PDF]

Toxins (Basel), 2023
Boss L, Kędzierska B.
europepmc   +1 more source

Bacterial toxin-antitoxin systems: Novel insights on toxin activation across populations and experimental shortcomings. [PDF]

Curr Res Microb Sci, 2023
Pizzolato-Cezar LR, Spira B, Machini MT.
europepmc   +1 more source