Results 91 to 100 of about 16,375 (172)

Type II Toxin-Antitoxin Systems in Escherichia coli [PDF]

He Zhang,1 Shuan Tao,2 Huimin Chen,2 Yewei Fang,2 Yao Xu,3 A-Xiang Han,2 Fang Ma,1,* Wei Liang2,* 1Department of Medical Laboratory, Bengbu Medical University, Bengbu, Anhui, People’s Republic of China; 2Department of Clinical Laboratory, The ...
Fang Y, Han AX, Liang W, Zhang H, Tao S, Chen H, Ma F, Xu Y   +7 more
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Toxin-antitoxin genes are differentially expressed in Escherichia coli relA and spoT mutans cultured under nitrogen, fatty acid, or carbon starvation conditions

Frontiers in Microbiology
IntroductionThe stringent response is one of the fundamental mechanisms that control and modulate bacterial adaptation to stress conditions, such as nutrient limitation.
Monika Maciąg-Dorszyńska, Paweł Olszewski, Monika Karczewska, Lidia Boss   +3 more
doaj   +1 more source

Orphan Toxin OrtT (YdcX) of Escherichia coli Reduces Growth during the Stringent Response

Toxins, 2015
Toxin/antitoxin (TA) systems are nearly universal in prokaryotes; toxins are paired with antitoxins which inactivate them until the toxins are utilized. Here we explore whether toxins may function alone; i.e., whether a toxin which lacks a corresponding ...
Sabina Islam, Michael J. Benedik, Thomas K. Wood   +2 more
doaj   +1 more source

Toxin-antitoxin systems in bacteria : mechanisms, targets and specificity [PDF]

, 2015
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Biology, 2015.Title as it appears in MIT Commencement Exercises program, June, 2015: Toxin-antitoxin systems in bacteria : targets, mechanisms, and specificity.
Aakre, Christopher David
core  

Bacterial toxin-antitoxin systems targeting translation [PDF]

, 2010
10 p.-2 fig.Toxin-antitoxin systems (TAS) emerged more than 25 years ago and have since developed as an important field in molecular microbiology. TAS are autoregulated operons coding a stable toxin and an unstable antitoxin found in the plasmids and ...
Ramón Díaz-Orejas, Concha Nieto, Nieto, Concha, López-Villarejo, Juan, Lemonnier, Marc, Hernández-Arriaga, A.M., Inma Moreno-Córdoba, Ana María Hernández Arriaga, Espinosa, Manuel, Marc Lemonnier, Moreno-Córdoba, Inmaculada, Manuel Espinosa, Díaz-Orejas, Ramón, Elizabeth Diago-Navarro, Diago-Navarro, Elizabeth, Juan López-Villarejo   +15 more
core   +1 more source

Bioinformatics and Functional Assessment of Toxin-Antitoxin Systems in Staphylococcus aureus

Toxins, 2018
Staphylococcus aureus is a nosocomial pathogen that can cause chronic to persistent infections. Among different mediators of pathogenesis, toxin-antitoxin (TA) systems are emerging as the most prominent.
Gul Habib, Qing Zhu, Baolin Sun
doaj   +1 more source

Proteolytic Regulation of Toxin-Antitoxin Systems by ClpPC in Staphylococcus aureus [PDF]

, 2009
Bacterial toxin-antitoxin (TA) systems typically consist of a small, labile antitoxin that inactivates a specific longer-lived toxin. In Escherichia coli, such antitoxins are proteolytically regulated by the ATP-dependent proteases Lon and ClpP.
Donegan, Niles P, Cheung, Ambrose L, Thompson, Earl T, Fu, Zhibiao   +3 more
core   +2 more sources

de novo synthesis of a bacterial toxin/antitoxin system [PDF]

, 2014
The prevalence of toxin/antitoxin (TA) systems in almost all genomes suggests they evolve rapidly. Here we show that an antitoxin from a type V system (GhoS, an endoribonuclease specific for the mRNA of the toxin GhoT) can be converted into a novel toxin
Soo, Valerie WC, Cheng, Hsin-Yao, Wood, Thomas K, Kwan, Brian W   +3 more
core   +1 more source

Viral evasion of a bacterial suicide system by RNA-based molecular mimicry enables infectious altruism.

PLoS Genetics, 2012
Abortive infection, during which an infected bacterial cell commits altruistic suicide to destroy the replicating bacteriophage and protect the clonal population, can be mediated by toxin-antitoxin systems such as the Type III protein-RNA toxin-antitoxin
Tim R Blower, Terry J Evans, Rita Przybilski, Peter C Fineran, George P C Salmond   +4 more
doaj   +1 more source

Characterization of Chromosomally Encoded Toxin-Antitoxin Systems in Streptococcus pyogenes [PDF]

, 2019
Streptococcus pyogenes ist ein humanpathogenes Bakterium, welches verschiedene Gewebe besiedeln kann und dadurch unterschiedliche Krankheiten verursacht.
Zarate Bonilla, Lina Johana, Bonilla, Lina Johana   +1 more
core   +1 more source