Results 41 to 50 of about 958,820 (304)
The actions of Pasteurella multocida toxin on neuronal cells [PDF]
, 2014 Pasteurella multocida toxin (PMT) activates the G-proteins Gα, Gα, Gα Gα and Gα by deamidation of specific glutamine residues. A number of these alpha subunits have signalling roles in neurones.
Lax, Alistair; id_orcid +13 more
core +1 more source
Monovalent and Multivalent Inhibitors of Bacterial Toxins [PDF]
, 2011 Cholera and travellers' diarrhoea are caused by AB5 protein toxins that bind to ganglioside GM1 at the surface of the cells lining the intestine. Inhibition of this protein-carbohydrate interaction would prevent the toxin from entering the cells, and thus prevents toxin-induced diarrhoea.
null Edward D. Hayes, W. Bruce Turnbull
openaire +3 more sources
Clostridium perfringens Delta-Toxin Damages the Mouse Small Intestine
Toxins, 2019 Clostridium perfringens strains B and C cause fatal intestinal diseases in animals. The secreted pore-forming toxin delta-toxin is one of the virulence factors of the strains, but the mechanism of intestinal pathogenesis is unclear. Here, we investigated
Soshi Seike +3 more
doaj +1 more source
Frontiers in Veterinary Science, 2022 Clostridium perfringens beta2 (CPB2) toxin, one of the virulence factors of Clostridium perfringens (C. perfringens), can cause necrotizing enterocolitis in piglets. Accumulating pieces of evidence indicate that microRNAs (miRNAs) refer to the regulation
Kaihui Xie +10 more
doaj +1 more source
Multivalent Inhibitors of Channel-Forming Bacterial Toxins [PDF]
, 2016 Rational design of multivalent molecules represents a remarkable modern tool to transform weak non-covalent interactions into strong binding by creating multiple finely-tuned points of contact between multivalent ligands and their supposed multivalent targets. Here, we describe several prominent examples where the multivalent blockers were investigated
Goli, Yamini, Ekaterina M, Nestorovich
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Constitutive expression of Vr-ERE gene in transformed grapevines confers enhanced resistance to eutypine, a toxin from Eutypa lata [PDF]
, 2003 Eutypine (4-hydroxy-3-[3-methyl-3-butene-1-ynyl] benzaldehyde) is a toxin produced by Eutypa lata , the causal agent of eutypa dieback of grapevines.
Bouquet, Alain +23 more
core +1 more source
Killer Toxins of Yeasts: Inhibitors of Fermentation and Their Adsorption
Journal of Food Protection, 1987 The killer toxin (KT 28), a glycoprotein of Saccharomyces cerevisiae strain 28, was almost completely adsorbed by bentonite, when applied at a concentration of 1 g per liter. No significant differences were found between several types of bentonite. Killer toxin KT 28 is similarly adsorbed by intact yeast cells or by a commercial preparation of yeast ...
Ferdinand, Radler, Manfred, Schmitt
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Further Characterization of Dopamine Release by Permeabilized PC 12 Cells [PDF]
, 1987 Rat pheochromocytoma cells (PC 12) permeabilized with staphylococcal α-toxin release [3H]dopamine after addition of micromolar Ca2+. This does not require additional Mg2+-ATP (in contrast to bovine adrenal medullary chromaffin cells).
Ahnert-Hilger, G. +3 more
core +1 more source
The Chaperonin TRiC/CCT Inhibitor HSF1A Protects Cells from Intoxication with Pertussis Toxin
ToxinsPertussis toxin (PT) is a bacterial AB5-toxin produced by Bordetella pertussis and a major molecular determinant of pertussis, also known as whooping cough, a highly contagious respiratory disease.
Jinfang Jia +4 more
doaj +1 more source
Cellular vacuoles induced by Mycoplasma pneumoniae CARDS toxin originate from Rab9-associated compartments. [PDF]
PLoS ONE, 2011 Recently, we identified an ADP-ribosylating and vacuolating cytotoxin in Mycoplasma pneumoniae designated Community Acquired Respiratory Distress Syndrome (CARDS) toxin.
Coreen Johnson +2 more
doaj +1 more source