Results 101 to 110 of about 3,656,607 (353)

The Languages Spoken in the Water Body (or the Biological Role of Cyanobacterial Toxins)

open access: yesFront. Microbio., 2012
Although intensification of toxic cyanobacterial blooms over the last decade is a matter of growing concern due to bloom impact on water quality, the biological role of most of the toxins produced is not known.
A. Kaplan   +5 more
semanticscholar   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Biological Activities of Stilbenoids

open access: yesInternational Journal of Molecular Sciences, 2018
Stilbenoids are a group of naturally occurring phenolic compounds found in various plant species. They share a common backbone structure known as stilbene, but differ in the nature and position of substituents. Stilbenoids are classified as phytoalexins,
Bolanle C Akinwumi   +2 more
semanticscholar   +1 more source

Biological effects of uremic toxins

open access: yesRomanian Journal of Infectious Diseases, 2015
Progressive accumulation of uremic toxins in the body exerts a variety of adverse effects on all organs, tissues and systems. The elimination of these compounds from the body is a major goal in the international scientific community. The objectives of this study are: uremic toxins classification, presentation of nocive effects of uremic toxins in human
Corina Daniela Ene   +3 more
openaire   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Biological indicators for pollution detection in terrestrial and aquatic ecosystems

open access: yesBulletin of the National Research Centre, 2020
Environmental pollution from varied sources is now deemed as one of the most serious problems everywhere. Several pollutants, however, could be perceived by certain biological indicators, each one is used to identify assured single or a category of ...
A. Zaghloul, M. Saber, S. Gadow, F. Awad
semanticscholar   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Microorganisms and their byproducts, nematodes, oils and particle films have important agricultural uses

open access: yesCalifornia Agriculture, 2005
The insect and mite control potential of natural and biological toxins has been recognized for several centuries. Bacteria, viruses, protozoa and fungi are the primary groups of microorganisms known to reduce insect populations; they often occur ...
L Godfrey   +3 more
doaj   +2 more sources

The Biological Properties of Bacterial Toxins

open access: yesВестник войск РХБ защиты
Knowledge of the biological properties of bacterial toxins is constantly being updated. Over the past two decades, the research interest has shifted from natural toxins to their genetically modified derivatives.
M. V. Supotnitskiy
doaj   +1 more source

Brown Spider (Loxosceles) Venom Toxins as Potential Biotools for the Development of Novel Therapeutics

open access: yesToxins, 2019
Brown spider envenomation results in dermonecrosis with gravitational spreading characterized by a marked inflammatory reaction and with lower prevalence of systemic manifestations such as renal failure and hematological disturbances. Several toxins make
Daniele Chaves-Moreira   +11 more
doaj   +1 more source

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