Results 101 to 110 of about 2,290 (178)
Widespread alternative exon usage in clinically distinct subtypes of Invasive Ductal Carcinoma
Cancer cells can have different patterns of exon usage of individual genes when compared to normal tissue, suggesting that alternative splicing may play a role in shaping the tumor phenotype.
Sunniva Stordal Bjørklund +14 more
doaj +1 more source
Background: Androgen steroid hormones are key drivers of prostate cancer. Previous work has shown that androgens can drive the expression of alternative mRNA isoforms as well as transcriptional changes in prostate cancer cells.
Jennifer Munkley +9 more
doaj +1 more source
Herstellung und Reinigung von TPD52-Fusionsproteinen zur Proteintransduktion von Säugetierzellen
Die Chemokinrezeptoren CCR2a und CCR2b sind an der Regulation zentraler Funktionen von leukozytären Zellen beteiligt. In Untersuchungen wurde mit Tumorprotein D52 (TPD52) ein neuer Nicht-G-Protein-Interaktionspartner der CCR2 Rezeptoren identifiziert.
openaire +1 more source
Abstract Nasopharyngeal carcinoma (NPC) is an important type of head and neck malignant cancer with geographical distribution. MicroRNA-449b-5p (miR-449b-5p) is related to the development of various cancers, while its function in NPC remains unknown.
Wei, Yin, Lei, Shi, Yanjiao, Mao
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Background Myasthenia gravis (MG) is a chronic autoimmune neuromuscular junction disorder mediated by autoantibodies. Existing diagnostic methods mainly rely on serum antibody detection and electrophysiological testing, which are limited by invasiveness ...
Jing Yang +8 more
doaj +1 more source
United European Gastroenterology Journal, Volume 13, Issue 9, Page 1818-1839, November 2025.
wiley +1 more source
Improved resistance to Eimeria acervulina infection in chickens due to dietary supplementation with garlic metabolites [PDF]
The effects of a compound including the secondary metabolites of garlic, propyl thiosulphinate (PTS) and propyl thiosulphinate oxide (PTSO), on the in vitro and in vivo parameters of chicken gut immunity during experimental Eimeria acervulina infection ...
Bravo, David +4 more
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TPD52 is a prognostic biomarker and potential therapeutic target for ER+/PR+/HER2+ breast cancer
Breast cancer (BRCA) represents a significant health challenge for women globally, with refractory cases showing resistance to current therapeutic strategies. The discovery of novel molecular markers and therapeutic targets is critical for improving outcomes in these patients. The primary aim of this study is to elucidate the role of tumor protein D52 (
Xiaolin, Cheng +5 more
openaire +2 more sources
TPD52和TPD52L2在胃癌中异常表达的临床病理特征分析和相关基因共表达意义研究
目的 应用生物信息学的方法探讨肿瘤蛋白D52(tumor protein D52,TPD52)和肿瘤蛋白D52样2(tumor protein D52-like 2,TPD52L2)在胃癌中异常表达的临床病理特征,并分析相关基因共表达的意义。方法 基于癌症基因组图谱(The Cancer Genome AHas, TCGA)获取数据,利用R语言软件包比较TPD52和TPD52L2在胃癌组织和癌旁组织中的差异表达与临床病理特征的相关性,并探索与免疫细胞浸润水平的情况,Kaplan ...
高夏青 +6 more
doaj
Comparative analysis of chromosome 8 copy number in paediatric solid tumours [PDF]
Chromosomal imbalances are of major significance in cancer initiation and progression. Gains of chromosome 8 in human cancer have been described by a number of authors and are amongst the most common cytogenetic events that occur.
Martin La Rotta, Nancy Yamile Del Pilar
core

