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Our recent study of the microRNA expression signature of prostate cancer (PCa) revealed that microRNA-224 (miR-224) is significantly downregulated in PCa tissues.
Rika Nishikawa +2 more
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AMPK targets a proto-oncogene TPD52 (isoform 3) expression and its interaction with LKB1 suppress AMPK-GSK3β signaling axis in prostate cancer [PDF]
Surender Singh Jadav, Ramesh Ummanni
exaly +2 more sources
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Circ_0060551 promotes the migration and invasion of cervical cancer by upregulating TPD52
American Journal of Reproductive Immunology, 2022AbstractProblemCervical cancer has been recognized as the second most common cancer in women worldwide. Previous studies have reported that some circular RNAs (circRNAs) can influence the progression of cervical cancer. However, more researches are still required to unveil the underlying mechanism of how circRNAs regulate the progression of such cancer.
Qi, Shi +3 more
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Overexpression, Amplification, and Androgen Regulation of TPD52 in Prostate Cancer
Cancer Research, 2004Abstract Gains in the long arm of chromosome 8 (8q) are believed to be associated with poor outcome and the development of hormone-refractory prostate cancer. Based on a meta-analysis of gene expression microarray data from multiple prostate cancer studies (D. R.
Mark A, Rubin +15 more
openaire +2 more sources
The Role of the Coiled-Coil Motif in Interactions Mediated by TPD52
Biochemical and Biophysical Research Communications, 2001TPD52 (D52)-like proteins are small coiled-coil motif-bearing proteins first identified through their expression in human breast carcinoma that mutually interact in hetero- and homomeric fashions. However, it has been unclear whether the coiled-coil motif is sufficient, or even necessary, for these interactions to occur.
P, Sathasivam +3 more
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