Results 21 to 30 of about 1,640 (122)

A gene network of uterine luminal epithelium organizes mouse blastocyst implantation

Reproductive Medicine and Biology, Volume 21, Issue 1, January/December 2022., 2022
Abstract Purpose The receptive endometrium is critical for blastocyst implantation. In mice, after blastocysts enter the uterine cavities on day 4 of pregnancy (day 1 = vaginal plug), blastocyst attachment is completed within 24 h, accompanied by dynamic interactions between the uterine luminal epithelium and the blastocysts.
Shizu Aikawa, Yasushi Hirota, Yamato Fukui, Chihiro Ishizawa, Rei IIda, Tetsuaki Kaku, Tomoyuki Hirata, Shun Akaeda, Takehiro Hiraoka, Mitsunori Matsuo, Yutaka Osuga   +10 more
wiley   +1 more source

The human RBPome: From genes and proteins to human disease [PDF]

, 2015
RNA binding proteins (RBPs) play a central role in mediating post transcriptional regulation of genes. However less is understood about them and their regulatory mechanisms.
Hashemikhabir, Seyedsasan, Janga, Sarath Chandra, Neelamraju, Yaseswini   +2 more
core   +1 more source

Global gene expression analysis of early response to chemotherapy treatment in ovarian cancer spheroids [PDF]

, 2008
Background Chemotherapy (CT) resistance in ovarian cancer (OC) is broad and encompasses diverse unrelated drugs, suggesting more than one mechanism of resistance.
Tetu Bernard, Bachvarova Magdalena, L'Espérance Sylvain, Mes-Masson Anne-Marie, Bachvarov Dimcho   +4 more
core   +2 more sources

Cis and Trans Effects of Human Genomic Variants on Gene Expression [PDF]

, 2014
This work was funded by the Louis-Jeantet Foundation (http://www.jeantet.ch/), the European Research Council (Grant ID: 260927 http://erc.europa.eu/), the Swiss National Foundation (Grant ID: 130342 http://www.snf.ch), NCCR Frontiers In Genetics (http ...
A Boyd, AC Nica, AC Nica, AH Talukder, Alfonso Buil, AR Wood, AS Dimas, BE Stranger, BE Stranger, BU Schraml, C Wallace, Christopher David Brown, David M. Evans, DF Conrad, DJ Gaffney, DL Nicolae, DM Greenawalt, Donald F. Conrad, E Grundberg, E Klopocki, EE Schadt, Emmanouil T. Dermitzakis, George Davey Smith, GR Abecasis, H Huang, HJ Westra, J Ding, J Millstein, J Zhu, JD Storey, JE Powell, JK Pickrell, John P. Kemp, Julien Bryois, K Hildner, Karen M. Ho, LA Hindorff, M Gutierrez-Arcelus, M Scutari, Matthew Hurles, ND Miller, NL Barbosa-Morais, Panos Deloukas, RW Jones, SB Montgomery, SB Montgomery, SJ Loughran, Stephen B. Montgomery, Susan Ring, T Lappalainen, TR Insel, W Wang, Y Li, Y Li   +53 more
core   +5 more sources

DNA methylation during human adipogenesis and the impact of fructose [PDF]

, 2020
Background Increased adipogenesis and altered adipocyte function contribute to the development of obesity and associated comorbidities. Fructose modified adipocyte metabolism compared to glucose, but the regulatory mechanisms and consequences for obesity
Corrado Priami, Giulia Tini, Greg T. Nolen, Gregory Lefebvre, Jim Kaput, Marie-Pier Scott-Boyer, Patrick Descombes, Rosario Lombardo, Sylviane M('(e))tairon, Vijayalakshmi Varma   +9 more
core   +4 more sources

MicroRNA-217 inhibits cell proliferation, invasion and migration by targeting Tpd52l2 in human pancreatic adenocarcinoma

Oncology Reports, 2017
MicroRNAs (miRNAs) play important roles in the regulation of various tumor biological processes including proliferation and apoptosis. miR-217 has been implicated in many types of cancer, whereas its expression and potential biological function in human pancreatic adenocarcinoma (HPAC) remain unclear.
Qiuyang, Chen, Peng, Wang, Yue, Fu, Xinchun, Liu, Wenbin, Xu, Jishu, Wei, Wentao, Gao, Kuirong, Jiang, Junli, Wu, Yi, Miao   +9 more
openaire   +3 more sources

Tumor protein D54 defines a new class of intracellular transport vesicles [PDF]

, 2019
Transport of proteins and lipids from one membrane compartment to another is via intracellular vesicles. We investigated the function of tumor protein D54 (TPD54/TPD52L2) and found that TPD54 was involved in multiple membrane trafficking pathways ...
Balch, Biesemann, Boncompain, Bonifacino, Bucci, Byrne, Byrne, Byrne, Byrne, Cao, Cheeseman, Chen, Dasari, Dunlop, Edgar, Gabrielle Larocque, Geuze, Gillingham, Gordon, Gordon, Harris, Hein, Hirst, Hou, Huang, Jimenez, Junutula, Kamili, Kitt, Klöpper, Kozik, Kulak, Li, McCaughey, Messenger, Miller, Nicholas I. Clarke, Nicholas J. Carter, Nourse, Orci, Peden, Penelope J. La-Borde, Perry, Proux-Gillardeaux, Raposo, Robinson, Schindelin, Shahheydari, Shen, Shin, Stephen J. Royle, Takamori, Thomas, Thomas, Tisdale, Vigers, Wandinger-Ness, Wilson, Wong, Wood, Xu, Yoshimura, Zhang, Zhen   +63 more
core   +1 more source

Global analysis of aberrant pre-mRNA splicing in glioblastoma using exon expression arrays

BMC Genomics, 2008
Background Tumor-predominant splice isoforms were identified during comparative in silico sequence analysis of EST clones, suggesting that global aberrant alternative pre-mRNA splicing may be an epigenetic phenomenon in cancer. We used an exon expression
Nixon Tamara J, Neubauer Valerie L, Bachinski Linda L, Tsavachidis Spiridon, Baggerly Keith A, Cheung Hannah C, Aldape Kenneth D, Cote Gilbert J, Krahe Ralf   +8 more
doaj   +1 more source

Mycobacterium bovis BCG Interferes with miR-3619-5p Control of Cathepsin S in the Process of Autophagy [PDF]

, 2016
Main survival mechanism of pathogenic mycobacteria is to escape inimical phagolysosomal environment inside the macrophages. Many efforts have been made to unravel the molecular mechanisms behind this process.
Agerer, Beers, Behar, Billeskov, Blankenberg, Bucci, Burgos-Portugal, Bustin, Chen, Christoforidis, Clemens, Dennis, Driessen, Flannagan, Fratti, Ghorpade, Gorvel, Gutierrez, Hoeke, Houben, Huang, Huang, Jung, Kanehisa, Kanehisa, Kimmey, Klionsky, Kruger, Kumar, Kumar, Lee, Livak, Ma, Pan, Pawar, Rajaram, Riese, Saegusa, Sanjuan, Schneider, Sharbati, Sharbati, Sharbati, Sharbati, Sharbati-Tehrani, Sharbati-Tehrani, Stewart, Sturgill-Koszycki, Sun, Tanida, Tili, Vandesompele, Vejnar, Vergne, Vieira, Walburger, Wang, Xu, Zhang, Zhou, zur Bruegge   +60 more
core   +2 more sources

Promyelocytic leukemia (PML) protein plays important roles in regulating cell adhesion, morphology, proliferation and migration.

PLoS ONE, 2013
PML protein plays important roles in regulating cellular homeostasis. It forms PML nuclear bodies (PML-NBs) that act like nuclear relay stations and participate in many cellular functions.
Mei Kuen Tang, Yong Jia Liang, John Yeuk Hon Chan, Sing Wan Wong, Elve Chen, Yao Yao, Jingyi Gan, Lihai Xiao, Hin Cheung Leung, Hsiang Fu Kung, Hua Wang, Kenneth Ka Ho Lee   +11 more
doaj   +1 more source