Journal of Comparative Neurology, Volume 530, Issue 11, Page 1773-1949, August 2022., 2022 By using a genetically modified mouse model and viral tracing approaches, we mapped both the anterograde and the retrograde projections of a subpopulation of neurons in the anterior paraventricular thalamic nucleus, molecularly defined by the expression of glucokinase (GckaPVT).
Sevasti Gaspari +4 more
wiley +1 more source
A gene network of uterine luminal epithelium organizes mouse blastocyst implantation
Reproductive Medicine and Biology, Volume 21, Issue 1, January/December 2022., 2022 Abstract Purpose The receptive endometrium is critical for blastocyst implantation. In mice, after blastocysts enter the uterine cavities on day 4 of pregnancy (day 1 = vaginal plug), blastocyst attachment is completed within 24 h, accompanied by dynamic interactions between the uterine luminal epithelium and the blastocysts.
Shizu Aikawa +10 more
wiley +1 more source
DNA methylation during human adipogenesis and the impact of fructose [PDF]
, 2020 Background Increased adipogenesis and altered adipocyte function contribute to the development of obesity and associated comorbidities. Fructose modified adipocyte metabolism compared to glucose, but the regulatory mechanisms and consequences for obesity
Corrado Priami +9 more
core +4 more sources
Mycobacterium bovis BCG Interferes with miR-3619-5p Control of Cathepsin S in the Process of Autophagy [PDF]
, 2016 Main survival mechanism of pathogenic mycobacteria is to escape inimical phagolysosomal environment inside the macrophages. Many efforts have been made to unravel the molecular mechanisms behind this process.
Agerer +60 more
core +2 more sources
PLoS ONE, 2013 PML protein plays important roles in regulating cellular homeostasis. It forms PML nuclear bodies (PML-NBs) that act like nuclear relay stations and participate in many cellular functions.
Mei Kuen Tang +11 more
doaj +1 more source
Identification of tumor-associated cassette exons in human cancer through EST-based computational prediction and experimental validation [PDF]
, 2010 Background: Many evidences report that alternative splicing, the mechanism which produces mRNAs and proteins with different structures and functions from the same gene, is altered in cancer cells.
Anselmo, Anna +10 more
core +3 more sources
Randomness and preserved patterns in cancer network
, 2014 Breast cancer has been reported to account for the maximum cases among all female cancers till date. In order to gain a deeper insight into the complexities of the disease, we analyze the breast cancer network and its normal counterpart at the proteomic ...
Jalan, Sarika +2 more
core +1 more source
Latent rank change detection for analysis of splice-junction microarrays with nonlinear effects
, 2011 Alternative splicing of gene transcripts greatly expands the functional capacity of the genome, and certain splice isoforms may indicate specific disease states such as cancer.
Burns, Suzanne +5 more
core +1 more source
Global gene expression analysis of early response to chemotherapy treatment in ovarian cancer spheroids [PDF]
, 2008 Background Chemotherapy (CT) resistance in ovarian cancer (OC) is broad and encompasses diverse unrelated drugs, suggesting more than one mechanism of resistance.
Bachvarov, Dimcho +4 more
core +3 more sources
Tumor protein D52 (TPD52): A novel B-cell/plasma-cell molecule with unique expression pattern and Ca2+-dependent association with annexin VI [PDF]
, 2005 We generated a murine monoclonal antibody (B28p) detecting an antigenic determinant shared by the immunoglobulin superfamily receptor translocation-associated 1 (IRTA1) receptor (the immunogen used to raise B28p) and an unrelated 28-kDa protein that was ...
A. Carbone +22 more
core +1 more source