GCN2:roles in tumour development and progression [PDF]
, 2022 GCN2 (general control nonderepessible 2) is an eIF2α kinase responsible for entirely rewiring the metabolism of cells when they are put under amino acid starvation stress.
Gold, Lyssa T., Masson, Glenn
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Randomness and preserved patterns in cancer network
, 2014 Breast cancer has been reported to account for the maximum cases among all female cancers till date. In order to gain a deeper insight into the complexities of the disease, we analyze the breast cancer network and its normal counterpart at the proteomic ...
Jalan, Sarika +2 more
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Tumor protein D52 (TPD52): A novel B-cell/plasma-cell molecule with unique expression pattern and Ca2+-dependent association with annexin VI [PDF]
, 2005 We generated a murine monoclonal antibody (B28p) detecting an antigenic determinant shared by the immunoglobulin superfamily receptor translocation-associated 1 (IRTA1) receptor (the immunogen used to raise B28p) and an unrelated 28-kDa protein that was ...
A. Carbone +22 more
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Quantitative SWATH-based proteomic profiling of urine for the identification of endometrial cancer biomarkers in symptomatic women [PDF]
, 2023 BackgroundA non-invasive endometrial cancer detection tool that can accurately triage symptomatic women for definitive testing would improve patient care.
Agnew, Heather +13 more
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Latent rank change detection for analysis of splice-junction microarrays with nonlinear effects
, 2011 Alternative splicing of gene transcripts greatly expands the functional capacity of the genome, and certain splice isoforms may indicate specific disease states such as cancer.
Burns, Suzanne +5 more
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A functional variant on 20q13.33 related to glioma risk alters enhancer activity and modulates expression of multiple genes. [PDF]
, 2021 Genome-wide association studies (GWAS) have identified single-nucleotide polymorphisms (SNPs) associated with glioma risk on 20q13.33, but the biological mechanisms underlying this association are unknown.
Adli, Mazhar +9 more
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Transcriptomes reflect the phenotypes of undifferentiated, granulocyte and macrophage forms of HL-60/S4 cells [PDF]
, 2017 Author Posting. © The Author(s), 2017. This is the author's version of the work. It is posted here by permission of Taylor & Francis for personal use, not for redistribution.
Jauch, Anna +4 more
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Multiple tests of association with biological annotation metadata
, 2008 We propose a general and formal statistical framework for multiple tests of association between known fixed features of a genome and unknown parameters of the distribution of variable features of this genome in a population of interest.
Mark J. Van Der Laan +4 more
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Tracing recombinant bovine somatotropin ab(use) through transcriptomics: the potential of bovine somatic cells in a multi-dose longitudinal study [PDF]
, 2019 In the European Union, the use of recombinant bovine somatotropin (rbST) in dairy cattle is forbidden. Monitoring rbST (ab)use by its direct detection in animal matrices still remains a challenging task. New monitoring methods based on indirect detection
Cepeda Sáez, Alberto +5 more
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Genome-wide screening identifies cell-cycle control as a synthetic lethal pathway with SRSF2P95H mutation [PDF]
, 2021 Current strategies to target RNA splicing mutant myeloid cancers proposes targeting the remaining splicing apparatus. This approach has only been modestly sensitizing and is also toxic to non-mutant-bearing wild-type cells.
Chalk, Alistair M. +5 more
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