Results 81 to 90 of about 8,275 (209)
International Journal of General Medicine, 2022 Wei Jia, Yi-Fu He, Xiao-Jun Qian, Jian Chen Department of Medical Oncology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230001, People’s Republic of ...
Jia W, He YF, Qian XJ, Chen J
doaj
Molecular Genetics &Genomic Medicine, Volume 14, Issue 1, January 2026.This study evaluated pharmacogenomic (PGx) calling from whole‐exome sequencing (WES) in 3562 Taiwanese individuals. Fourteen pharmacogenes were reliably identified, with each person carrying an average of ~2.4 actionable phenotypes. The high actionable frequencies of G6PD deficiency and HLA‐B*58:01 highlight ethnic differences and support WES as a ...
Hsu‐Heng Lin +9 more
wiley +1 more source
Pharmacogenetics – individualized treatment of genetic disorders [PDF]
, 2011 Farmakogenetika je grana znanosti koja proučava povezanost genotipa sa različitom reakcijom na terapiju nekim lijekovima. Potencijal farmakogenetike je velik jer će dobiveni rezultati istraživanja omogućiti i olakšati individualizirano liječenje ...
Biluš, Mirna
core +2 more sources
Collective Effects in Linear Spectroscopy of Dipole-Coupled Molecular Arrays [PDF]
, 2014 We present a consistent analysis of linear spectroscopy for arrays of nearest neighbor dipole-coupled two-level molecules that reveals distinct signatures of weak and strong coupling regimes separated for infinite size arrays by a quantum critical point.
Abolins, B. P. +5 more
core +3 more sources
Beyond the Skin: Can Genetic Variants Predict Crohn's Disease in Psoriasis Patients?
International Journal of Dermatology, Volume 65, Issue 3, Page 425-426, March 2026.
Yuval Ramot
wiley +1 more source
CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 1, January 2026.ABSTRACT Pediatric extrapolation strategies issued by health authorities have streamlined pediatric drug development and reduced the unnecessary burden of conducting pediatric clinical studies. In line with these strategies, physiologically based pharmacokinetic (PBPK) models have been utilized extensively for initial dosing regimen and sampling ...
James W. T. Yates +26 more
wiley +1 more source
Development of a Scalable Pharmacogenomic Clinical Decision Support Service [PDF]
, 2014 Advances in sequencing technology are making genomic data more accessible within the healthcare environment. Published pharmacogenetic guidelines attempt to provide a clinical context for specific genomic variants; however, the actual implementation to ...
Brownstein, Catherine +7 more
core
Drug metabolizing enzyme activities versus genetic variances for drug of clinical pharmacogenomic relevance [PDF]
, 2011 Enzymes are critically important in the transportation, metabolism, and clearance of most therapeutic drugs used in clinical practice today. Many of these enzymes have significant genetic polymorphisms that affect the enzyme's rate kinetics.
Alan H B Wu
core +2 more sources
Pharmacogenomics and Personalized Medicine, 2017 Rachid Abaji,1 Maja Krajinovic2 1Department of Pharmacology, 2Departments of Pediatrics and Pharmacology, CHU Sainte-Justine Research Center, University of Montreal, Montreal, QC, Canada Abstract: The thiopurine S-methyltransferase (TPMT) gene encodes ...
Abaji R, Krajinovic M
doaj
Frontiers in Genetics, 2013 Multilocus genotypes have been shown to be of relevance for using pharmacogenomic principles to individualize drug therapy. As it relates to thiopurine therapy, genetic polymorphisms of TPMT are strongly associated with the pharmacokinetics and clinical ...
Gabriele eStocco +7 more
doaj +1 more source