Results 231 to 240 of about 1,089,122 (265)

Immunometabolic mechanisms of osteosarcopenic obesity: chronic inflammation, trained immunity, and systemic immune dysregulation. [PDF]

Front Immunol
Jiang H, Zhang Y, Luo Z, Tang X, He Y, Hao G.   +5 more
europepmc   +1 more source

From Chronic Inflammation to Cancer: The Role of Trained Immunity in IBD-Associated Colorectal Carcinogenesis. [PDF]

Med Sci (Basel)
Sipos F, Műzes G.
europepmc   +1 more source

Trained immunity in cancer and autoimmunity: a double-edged sword in immune memory reprogramming. [PDF]

Front Immunol
Salari N, Shams M, Razavi FT, Yazdanpanah E, Oksenych V, Haghmorad D.   +5 more
europepmc   +1 more source

Erratum for the Research Article "Systemically inducing trained immunity overcomes solid tumors' immunosuppressive microenvironment" by B. Priem <i>et al</i>.

Sci Adv
europepmc   +1 more source

Immunometabolic control of trained immunity [PDF]

Molecular Aspects of Medicine, 2021
Contains fulltext : 232180.pdf (Publisher’s version ) (Open Access)Innate immune cells can adopt long-term inflammatory phenotypes following brief encounters with exogenous (microbial) or endogenous stimuli.
Simone Moorlag, Niels P Riksen
exaly   +8 more sources

The role of neutrophils in trained immunity [PDF]

Immunological Reviews, 2023
The principle of trained immunity represents innate immune memory due to sustained, mainly epigenetic, changes triggered by endogenous or exogenous stimuli in bone marrow (BM) progenitors (central trained immunity) and their innate immune cell progeny ...
George Hajishengallis, Lydia Kalafati, Triantafyllos Chavakis   +2 more
exaly   +6 more sources

Trained Immunity: Reprogramming Innate Immunity in Health and Disease [PDF]

Annual Review of Immunology, 2021
Traditionally, the innate and adaptive immune systems are differentiated by their specificity and memory capacity. In recent years, however, this paradigm has shifted: Cells of the innate immune system appear to be able to gain memory characteristics ...
Leo A.B. Joosten, Simone Moorlag, Niels P Riksen   +2 more
exaly   +1 more source

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Trained innate immunity

Immunologic Research, 2021
The innate immune system acts rapidly in an identical and nonspecific way every time the body is exposed to pathogens. As such, it cannot build and maintain immunological memory to help prevent reinfection. Researchers contend that trained immunity is influenced by intracellular metabolic pathways and epigenetic remodeling.
openaire   +2 more sources

Immunometabolic Pathways in BCG-Induced Trained Immunity [PDF]

Cell Reports, 2016
Contains fulltext : 167302.pdf (Publisher’s version ) (Open Access)The protective effects of the tuberculosis vaccine Bacillus Calmette-Guerin (BCG) on unrelated infections are thought to be mediated by long-term metabolic changes and ...
Luís G Gonçalves, Leo A.B. Joosten, Reinout van Crevel   +2 more
exaly   +3 more sources

Trained immunity: adaptation within innate immune mechanisms

Physiological Reviews, 2023
The mechanisms underlying innate immune memory have been extensively explored in the last decades but are in fact largely unknown. Although the specificity of adaptive immune memory in vertebrates is ensured through the recombination of immunoglobulin family genes and clonal expansion, the basic mechanisms of innate immune cells’ nonspecific increased
Leo A.B. Joosten, Willem J.M. Mulder, Niels P Riksen   +2 more
exaly   +4 more sources