Results 31 to 40 of about 3,929,670 (363)
RNF12 activates Xist and is essential for X chromosome inactivation. [PDF]
PLoS Genetics, 2011 In somatic cells of female placental mammals, one of the two X chromosomes is transcriptionally silenced to accomplish an equal dose of X-encoded gene products in males and females.
Tahsin Stefan Barakat +9 more
doaj +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 1989 The known primate lentiviruses can be divided into two subgroups consisting of the human immunodeficiency virus type 1 (HIV-1) isolates and the related HIV type 2 (HIV-2) and simian immunodeficiency virus (SIV) isolates.
M. Malim +5 more
semanticscholar +1 more source
Signal Transduction and Targeted Therapy, 2023 Cancer cell receives extracellular signal inputs to obtain a stem-like status, yet how tumor microenvironmental (TME) neural signals steer cancer stemness to establish the hierarchical tumor architectures remains elusive.
Bin He +22 more
doaj +1 more source
A Novel Method for Gene-Specific Enhancement of Protein Translation by Targeting 5'UTRs of Selected Tumor Suppressors. [PDF]
PLoS ONE, 2016 BACKGROUND:Translational control is a mechanism of protein synthesis regulation emerging as an important target for new therapeutics. Naturally occurring microRNAs and synthetic small inhibitory RNAs (siRNAs) are the most recognized regulatory molecules ...
Adam Master +5 more
doaj +1 more source
Journal of General Virology, 1993 We have produced monoclonal antibodies against two Orgyia pseudotsugata multicapsid nuclear polyhedrosis virus (OpMNPV) transcriptional trans-activators, IE-1 and IE-2.
D. Theilmann, S. Stewart
semanticscholar +1 more source
Insects, 2021 Small heat shock proteins (sHSPs) are members of the heat shock protein (HSP) family that play an important role in temperature stress, and heat shock factors (HSFs) are transcriptional activators that regulate HSP expression. Cotesia chilonis, the major
Fu-Jing He +3 more
doaj +1 more source
An emerging and variant viral promoter of HIV-1 subtype C exhibits low-level gene expression noise
Retrovirology, 2021 Background We observe the emergence of several promoter-variant viral strains in India during recent years. The variant viral promoters contain additional copies of transcription factor binding sites present in the viral modulatory region or enhancer ...
Haider Ali +7 more
doaj +1 more source
Synergy between HIV-1 Tat and adenovirus E1A is principally due to stabilization of transcriptional elongation [PDF]
, 1990 We studied the combined effects of Tat and general trans-activators, such as E1A and phorbol esters, on human immunodeficiency virus-1 (HIV-1) gene expression. Interaction between these two types of trans-activators may be involved in the transition from
Laspia, M. F. +2 more
core +1 more source
Negative regulation of Sp1 trans-activation is correlated with the binding of cellular proteins to the amino terminus of the Sp1 trans-activation domain. [PDF]
Journal of Biological Chemistry, 1994 Sp1 is a well characterized and ubiquitously expressed transcription factor that regulates the constitutive and induced expression of a variety of mammalian genes. It is unclear whether Sp1 activity is regulated in vivo; the mechanism by which Sp1 interacts with the basal transcription complex has not been firmly established.
Ava J. Udvadia +4 more
openaire +2 more sources
Cross regulation of sirtuin 1, AMPK, and PPARγ in conjugated linoleic acid treated adipocytes. [PDF]
PLoS ONE, 2012 Trans-10, cis-12 conjugated linoleic acid (t10c12 CLA) reduces triglyceride (TG) levels in adipocytes through multiple pathways, with AMP-activated protein kinase (AMPK) generally facilitating, and peroxisome proliferator-activated receptor γ (PPARγ ...
Shan Jiang +3 more
doaj +1 more source