Results 41 to 50 of about 807,190 (203)
Conservation of the TRAPPII-specific subunits of a Ypt/Rab exchanger complex
BMC Evolutionary Biology, 2007 Background Ypt/Rab GTPases and their GEF activators regulate intra-cellular trafficking in all eukaryotic cells. In S. cerivisiae, the modular TRAPP complex acts as a GEF for the Golgi gatekeepers: Ypt1 and the functional pair Ypt31/32.
Yoo Eunice +3 more
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Cis- and Trans-Activation of Hormone Receptors: the LH Receptor [PDF]
Molecular Endocrinology, 2002 AbstractG protein-coupled receptors (GPCRs) accommodate a wide spectrum of activators from ions to glycoprotein hormones. The mechanism of activation for this large and clinically important family of receptors is poorly understood. Although initially thought to function as monomers, there is a growing body of evidence that GPCR dimers form, and in some
Inhae, Ji +4 more
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Trans-activation of heparanase promoter by ETS transcription factors [PDF]
Oncogene, 2003 The remodeling of extracellular matrix (ECM) is an important process required for cancer cells to turn into invasive and metastatic cancer cells. To dissolve the protein components of ECM, matrix metalloproteinases are some of the essential enzymes. Another ECM remodeling enzyme is the heparanase (Hpa) that digests the heparin sulfate component of the ...
W C, Lu, Y N, Liu, B B, Kang, J H, Chen
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[Passengers on Board Trans-Texas Airways Plane] [PDF]
, 1955 Photograph of a Trans-Texas Airways pilot and a family of passengers standing alongside the plane, as if about to board. The pilot holds a ticket which the father and one son look at. The mother and a younger son look on. "Trans-Texas Airways" and a logo
Douglass, Neal
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Communications BiologyCas12 and Cas13 are extensively utilized in molecular diagnostics for their trans-cleavage activities, yet their activation characteristics remain partially understood. Here, we conduct an in-depth investigation of Cas12a, Cas12f1, and Cas13a, uncovering
Qing Wu +7 more
doaj +1 more source
Characterization of the transcriptional trans activator of human foamy retrovirus [PDF]
Journal of Virology, 1991 The human foamy viruses, or spumaviruses, a distinct subfamily of complex human retroviruses, remain poorly understood both in terms of their pathogenic potential and in terms of the regulatory mechanisms that govern their replication. Here, we demonstrate that the human spumaretrovirus shares with other complex human retroviruses the property of ...
A, Keller +5 more
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The small FNR regulon of Neisseria gonorrhoeae: comparison with the larger Escherichia coli FNR regulon and interaction with the NarQ-NarP regulon [PDF]
, 2007 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work
Cole, JA +28 more
core +2 more sources
Specific multivalent molecules boost CRISPR-mediated transcriptional activation
Nature CommunicationsCRISPR/Cas-based transcriptional activators can be enhanced by intrinsically disordered regions (IDRs). However, the underlying mechanisms are still debatable.
Rui Chen +15 more
doaj +1 more source
trans-Activation of a globin promoter in nonerythroid cells. [PDF]
Molecular and Cellular Biology, 1991 We show that expression in fibroblasts of a single cDNA, encoding the erythroid DNA-binding protein Eryf1 (GF-1, NF-E1), very efficiently activates transcription of a chicken alpha-globin promoter, trans-Activation in these cells occurred when Eryf1 bound to a single site within a minimal globin promoter.
T, Evans, G, Felsenfeld
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Trans-Texas Airways schedules February 1952 [PDF]
, 1952 Pamphlet containing schedules for Trans-Texas Airways during February ...
Trans Texas Airways
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