A Novel Method for Gene-Specific Enhancement of Protein Translation by Targeting 5'UTRs of Selected Tumor Suppressors. [PDF]
PLoS ONE, 2016 BACKGROUND:Translational control is a mechanism of protein synthesis regulation emerging as an important target for new therapeutics. Naturally occurring microRNAs and synthetic small inhibitory RNAs (siRNAs) are the most recognized regulatory molecules ...
Adam Master +5 more
doaj +1 more source
Inter-freundlicher Umgang in der Medizin / Trans-freundlicher Umgang in der Medizin [PDF]
, 2020 Ziel: Anliegen dieses Videos ist für einen inter*- und trans*-freundlichen Umgang in der Medizin zu sensibilisieren.Goal: The purpose of this video is to raise awareness of inter* and trans* -friendly handling in ...
core +1 more source
An emerging and variant viral promoter of HIV-1 subtype C exhibits low-level gene expression noise
Retrovirology, 2021 Background We observe the emergence of several promoter-variant viral strains in India during recent years. The variant viral promoters contain additional copies of transcription factor binding sites present in the viral modulatory region or enhancer ...
Haider Ali +7 more
doaj +1 more source
The cAMP Inducers Modify N-Acetylaspartate Metabolism in Wistar Rat Brain
Antioxidants, 2021 Neuronal N-acetylaspartate production appears in the presence of aspartate N-acetyltransferase (NAT8L) and binds acetyl groups from acetyl-CoA with aspartic acid.
Robert Kowalski +5 more
doaj +1 more source
Intranuclear topological distribution of HIV‐1 trans‐activators [PDF]
FEBS Letters, 1992 Subcellular localization of human immunodeficiency virus type 1 (HIV‐1) Tat and Rev was examined using a confocal laser scanning microscope (CLSM). In transfected COS‐7 cells, Tat resided exclusively in the perinocleolar region, while Rev infiltrated fully into the nucleoli.
Miyazaki, Yukio +4 more
openaire +2 more sources
Insects, 2021 Small heat shock proteins (sHSPs) are members of the heat shock protein (HSP) family that play an important role in temperature stress, and heat shock factors (HSFs) are transcriptional activators that regulate HSP expression. Cotesia chilonis, the major
Fu-Jing He +3 more
doaj +1 more source
Trans-itioning lives, trans-forming places [PDF]
, 2023 Trans-itioning lives, trans-forming ...
Merinda Kelly (14287493) +4 more
core
Trans Time: Safety, Privacy, and Content Warnings on a Transgender-Specific Social Media Site [PDF]
, 2020 Trans people often use social media to connect with others, find and share resources, and post transition-related content. However, because most social media platforms are not built with trans people in mind and because online networks include people who
Haimson, Oliver L. +5 more
core +1 more source
Management of Recurrent Retroperitoneal Sarcoma (RPS) in the Adult: A Consensus Approach from the Trans-Atlantic RPS Working Group [PDF]
, 2016 Retroperitoneal soft tissue sarcomas (RPS) are rare tumors. Surgery is the mainstay of curative therapy, but local recurrence is common. No recommendations concerning the best management of recurring disease have been developed so far.
Jakob, Jens +1 more
core +1 more source
Cross regulation of sirtuin 1, AMPK, and PPARγ in conjugated linoleic acid treated adipocytes. [PDF]
PLoS ONE, 2012 Trans-10, cis-12 conjugated linoleic acid (t10c12 CLA) reduces triglyceride (TG) levels in adipocytes through multiple pathways, with AMP-activated protein kinase (AMPK) generally facilitating, and peroxisome proliferator-activated receptor γ (PPARγ ...
Shan Jiang +3 more
doaj +1 more source