Results 31 to 40 of about 897,116 (253)

Trans Accessible Libraries Initiative [PDF]

open access: yes, 2023
Presentation highlighting the Trans Accessible Libraries Initiative at the University of North Texas Libraries. The Trans Accessible Libraries Initiative aims to remove some of the barriers trans individuals face accessing information and to provide more
Condrey, Coby, Leuzinger, Julie
core  

Inter-freundlicher Umgang in der Medizin / Trans-freundlicher Umgang in der Medizin

open access: yes, 2020
Ziel: Anliegen dieses Videos ist für einen inter*- und trans*-freundlichen Umgang in der Medizin zu sensibilisieren.Goal: The purpose of this video is to raise awareness of inter* and trans* -friendly handling in ...

core   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Conservation of the TRAPPII-specific subunits of a Ypt/Rab exchanger complex

open access: yesBMC Evolutionary Biology, 2007
Background Ypt/Rab GTPases and their GEF activators regulate intra-cellular trafficking in all eukaryotic cells. In S. cerivisiae, the modular TRAPP complex acts as a GEF for the Golgi gatekeepers: Ypt1 and the functional pair Ypt31/32.
Yoo Eunice   +3 more
doaj   +1 more source

Cis- and Trans-Activation of Hormone Receptors: the LH Receptor [PDF]

open access: yesMolecular Endocrinology, 2002
AbstractG protein-coupled receptors (GPCRs) accommodate a wide spectrum of activators from ions to glycoprotein hormones. The mechanism of activation for this large and clinically important family of receptors is poorly understood. Although initially thought to function as monomers, there is a growing body of evidence that GPCR dimers form, and in some
Inhae, Ji   +4 more
openaire   +2 more sources

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Posttranscriptional trans-activation in cauliflower mosaic virus

open access: yesCell, 1989
The ability of plant cells to translate dicistronic mRNAs that mimic a segment of the polycistronic 35S RNA from cauliflower mosaic virus has been tested. The chloramphenicol acetyltransferase and beta-glucuronidase open reading frames (ORFs) were fused in-frame to the second viral cistron (ORF I).
Bonneville JM   +3 more
openaire   +3 more sources

Trans-activation of heparanase promoter by ETS transcription factors [PDF]

open access: yesOncogene, 2003
The remodeling of extracellular matrix (ECM) is an important process required for cancer cells to turn into invasive and metastatic cancer cells. To dissolve the protein components of ECM, matrix metalloproteinases are some of the essential enzymes. Another ECM remodeling enzyme is the heparanase (Hpa) that digests the heparin sulfate component of the ...
W C, Lu, Y N, Liu, B B, Kang, J H, Chen
openaire   +2 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Harnessing noncanonical trans-cleavage characteristics of Cas12 and Cas13a to enhance CRISPR-based diagnostics

open access: yesCommunications Biology
Cas12 and Cas13 are extensively utilized in molecular diagnostics for their trans-cleavage activities, yet their activation characteristics remain partially understood. Here, we conduct an in-depth investigation of Cas12a, Cas12f1, and Cas13a, uncovering
Qing Wu   +7 more
doaj   +1 more source

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