Insects, 2021 Small heat shock proteins (sHSPs) are members of the heat shock protein (HSP) family that play an important role in temperature stress, and heat shock factors (HSFs) are transcriptional activators that regulate HSP expression. Cotesia chilonis, the major
Fu-Jing He +3 more
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Cell-Cycle Dependence of Transcription Dominates Noise in Gene Expression [PDF]
, 2013 The large variability in mRNA and protein levels found from both static and dynamic measurements in single cells has been largely attributed to random periods of transcription, often occurring in bursts.
A Bar-Even +72 more
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Cross regulation of sirtuin 1, AMPK, and PPARγ in conjugated linoleic acid treated adipocytes. [PDF]
PLoS ONE, 2012 Trans-10, cis-12 conjugated linoleic acid (t10c12 CLA) reduces triglyceride (TG) levels in adipocytes through multiple pathways, with AMP-activated protein kinase (AMPK) generally facilitating, and peroxisome proliferator-activated receptor γ (PPARγ ...
Shan Jiang +3 more
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RelA/NF-kappaB recruitment on the bax gene promoter antagonizes p73-dependent apoptosis in costimulated T cells [PDF]
, 2008 The balance between antiapoptotic and proapoptotic proteins of the Bcl-2 family is critical in determining the fate of T cells in response to death stimuli.
A., Annibaldi +7 more
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Role of hepatitis B surface antigen in the development of hepatocellular carcinoma: regulation of lymphoid enhancer-binding factor 1 [PDF]
, 2009 Background There are around 350 million of hepatitis B surface antigen (HBsAg) carriers worldwide, and among them, high risk of developing hepatocellular carcinoma (HCC) has been identified by epidemiological studies. To date, the molecular role of HBsAg
Tian Xiaochen +5 more
core +2 more sources
Posttranscriptional trans-activation in cauliflower mosaic virus
Cell, 1989 The ability of plant cells to translate dicistronic mRNAs that mimic a segment of the polycistronic 35S RNA from cauliflower mosaic virus has been tested. The chloramphenicol acetyltransferase and beta-glucuronidase open reading frames (ORFs) were fused in-frame to the second viral cistron (ORF I).
J M, Bonneville +3 more
openaire +2 more sources
Mechanisms of stimulation of SAGA-mediated nucleosome acetylation by a transcriptional activator
Biochemistry and Biophysics Reports, 2021 Eukaryotic gene expression requires the coordination of multiple factors to overcome the repressive nature of chromatin. However, the mechanistic details of this coordination are not well understood.
Sannie J. Culbertson +1 more
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Lineage-specific Gene Expression in the Sea Urchin Embryo [PDF]
, 1985 Within a few days of fertilization, the sea urchin embryo develops into a small differentiated organism consisting of about 1800 cells and capable of feeding, swimming, and the further ontogenic transformations required in the succeeding weeks of larval ...
Davidson, E. H. +5 more
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Metabolomic and physiological analysis of bud differentiation in dense apple (Malus×domestica Borkh.) orchards following thinning and reshaping [PDF]
PeerJBackground In China, a majority of apple orchards were initially planted under arboriculture. The branch number increases, causing a deterioration of the canopy light conditions as the trees age.
Zehua Yang +4 more
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Manipulating chromatin architecture in C. elegans
Epigenetics & Chromatin, 2022 Background Nucleosome-mediated chromatin compaction has a direct effect on the accessibility of trans-acting activators and repressors to DNA targets and serves as a primary regulatory agent of genetic expression. Understanding the nature and dynamics of
John L. Carter +3 more
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