Results 61 to 70 of about 54,904 (301)
Molecules, 2010 Colorectal cancer (CRC) is a major cause of tumor-related morbidity and mortality worldwide. Recent research suggests that pharmacological intervention using dietary factors that activate the redox sensitive Nrf2/Keap1-ARE signaling pathway may represent
Georg Thomas Wondrak +5 more
doaj +1 more source
Epstein-Barr virus genetics: talking about the BAC generation [PDF]
, 2010 Genetic mutant organisms pervade all areas of Biology. Early on, herpesviruses (HV) were found to be amenable to genetic analysis using homologous recombination techniques in eukaryotic cells.
Regina Feederle +2 more
core +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Nature CommunicationsThe Arabidopsis thaliana DREB2A transcription factor interacts with the negative regulator RCD1 and the ACID domain of subunit 25 of the transcriptional co-regulator mediator (Med25) to integrate stress signals for gene expression, with elusive molecular
Frederik Friis Theisen +9 more
doaj +1 more source
Two distinct forms of active transcription factor CREB (cAMP response element binding protein) [PDF]
, 1990 Mammalian cells express two distinct forms of transcription factor CREB (cAMP response element binding protein) that are apparently the products of alternative splicing of the CREB gene transcript.
Berkowitz, L. A., Gilman, M. Z.
core +1 more source
Introduction: Affective Histories of Queer and Trans Activism
SQS – Suomen Queer-tutkimuksen Seuran lehti, 2023 Non peer ...
Alasuutari, Varpu +4 more
openaire +3 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Light-dependent roles of the G-protein α subunit GNA1 of Hypocrea jecorina (anamorph Trichoderma reesei) [PDF]
, 2009 Background The filamentous ascomycete Hypocrea jecorina (anamorph Trichoderma reesei) is primarily known for its efficient enzymatic machinery that it utilizes to decompose cellulosic substrates.
André Schuster +5 more
core +3 more sources
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Alternative splicing of activator CcbHLH1 gene accounts for anthocyanin absence in white cornflower
Ornamental Plant ResearchAnthocyanins play crucial roles in conferring multicolored characteristics to higher plant organs. Previous studies have investigated the absence of anthocyanin accumulation in white cornflower petals, where the anthocyanin biosynthesis pathway was ...
Chengyan Deng +9 more
doaj +1 more source