Results 41 to 50 of about 3,929,670 (363)

The cAMP Inducers Modify N-Acetylaspartate Metabolism in Wistar Rat Brain

Antioxidants, 2021
Neuronal N-acetylaspartate production appears in the presence of aspartate N-acetyltransferase (NAT8L) and binds acetyl groups from acetyl-CoA with aspartic acid.
Robert Kowalski, Piotr Pikul, Krzysztof Lewandowski, Monika Sakowicz-Burkiewicz, Tadeusz Pawełczyk, Marlena Zyśk   +5 more
doaj   +1 more source

Trans-activators Regulating Neuronal Glucose Transporter Isoform-3 Gene Expression in Mammalian Neurons*

Journal of Biological Chemistry, 2004
The murine facilitative glucose transporter isoform 3 is developmentally regulated and is predominantly expressed in neurons. By employing the primer extension assay, the transcription start site of the murine Glut 3 gene in the brain was localized to ...
A. Rajakumar, S. Thamotharan, N. Raychaudhuri, R. Menon, S. Devaskar   +4 more
semanticscholar   +1 more source

RelA/NF-kappaB recruitment on the bax gene promoter antagonizes p73-dependent apoptosis in costimulated T cells [PDF]

, 2008
The balance between antiapoptotic and proapoptotic proteins of the Bcl-2 family is critical in determining the fate of T cells in response to death stimuli.
A., Annibaldi, A., Costanzo, B., Marinari, Levrero, Massimo, Muscolini, Michela, R., Cianfrocca, Tuosto, Loretta, V., Marzano   +7 more
core   +1 more source

Trans-activation of heparanase promoter by ETS transcription factors [PDF]

Oncogene, 2003
The remodeling of extracellular matrix (ECM) is an important process required for cancer cells to turn into invasive and metastatic cancer cells. To dissolve the protein components of ECM, matrix metalloproteinases are some of the essential enzymes. Another ECM remodeling enzyme is the heparanase (Hpa) that digests the heparin sulfate component of the ...
B B Kang, W C Lu, J. H. Chen, Y N Liu
openaire   +3 more sources

Identification and function of human cytomegalovirus microRNAs [PDF]

, 2008
microRNAs are an extensive class of non-coding genes that regulate gene expression through post-transcriptional repression. These small RNAs are evolutionarily conserved and are likely to be a basic mechanism of gene regulation present within most ...
Bartel, Bernstein, Brennecke, Burnside, Cai, Cai, Cui, Doench, Dunn, Dunn, Elbashir, Elbashir, Enright, Finn Grey, Greaves, Grey, Grey, Grishok, Gupta, Hammond, Hutvagner, Hutvagner, Jay Nelson, John, Johnston, Ketting, Lee, Lee, Lee, Lim, Lu, Lund, Mocarski, Mourelatos, Pfeffer, Pfeffer, Rhoades, Samols, Sano, Simon, Stenberg, Stenberg, Stenberg, Stenberg, Stern-Ginossar, Sullivan, White, White, Wightman, Yang, Yao, Yekta, Yi, Zeng   +53 more
core   +1 more source

Functional interaction of STAT3 transcription factor with the coactivator NcoA/SRC1a. [PDF]

, 2002
Signal transducer and activator of transcription 3 (STAT3) transcription factors are cytoplasmic proteins that induce gene activation in response to cytokine receptor stimulation.
D.M. Heery, F. Bienvenu, H. Gascan, O. Coqueret, S. Avril, S. Giraud   +5 more
core   +2 more sources

Activation of the U2 snRNA promoter by the octamer motif defines a new class of RNA polymerase II enhancer elements [PDF]

, 1988
The recent discovery that the activation domains of transcriptional activators (e.g., GAL4) from a number of species are interchangeable has led to the concept of a general mechanism for activation of RNA polymerase II genes.
Grossniklaus, U., Hernandez, N., Herr, W., Tanaka, M.   +3 more
core   +1 more source

Manipulating chromatin architecture in C. elegans

Epigenetics & Chromatin, 2022
Background Nucleosome-mediated chromatin compaction has a direct effect on the accessibility of trans-acting activators and repressors to DNA targets and serves as a primary regulatory agent of genetic expression. Understanding the nature and dynamics of
John L. Carter, Colton E. Kempton, Emily D. S. Hales, Steven M. Johnson   +3 more
doaj   +1 more source

Neuronal glucose transporter isoform 3 deficient mice demonstrate features of autism spectrum disorders. [PDF]

, 2010
Neuronal glucose transporter (GLUT) isoform 3 deficiency in null heterozygous mice led to abnormal spatial learning and working memory but normal acquisition and retrieval during contextual conditioning, abnormal cognitive flexibility with intact gross ...
Devaskar, SU, Ehninger, D, Fung, C, Sankar, R, Shin, B-C, Shin, D, Silva, A, Thamotharan, S, Zhao, Y   +8 more
core   +2 more sources

Arabidopsis thaliana class-II TGA transcription factors are essential activators of jasmonic acid/ethylene-induced defense responses.

The Plant Journal, 2009
The three closely related Arabidopsis basic leucine zipper (bZIP) transcription factors TGA2, TGA5 and TGA6 are required for the establishment of the salicylic acid (SA)-dependent plant defense response systemic acquired resistance, which is effective ...
Mark Zander, Sylvain La Camera, Olivier Lamotte, J. Metraux, C. Gatz   +4 more
semanticscholar   +1 more source