Results 31 to 40 of about 675,014 (180)

Solvent-dependent regioselective oxidation of trans-chalcones using aqueous hydrogen peroxide [PDF]

Journal of the Brazilian Chemical Society, 2013
A novel method for regioselective oxidation of trans-chalcones with hydrogen peroxide in acetonitrile to afford cinnamic acids is reported. Only trans-b-arylacrylic acids were observed. A wide range of functionalized products can be effectively produced from various chalcones in good to excellent yields.
Peng Wang, Jin Cai, Jiabin Yang, Chunlong Sun, Li Lushen, Min Ji   +5 more
openalex   +6 more sources

Trans-chalcone induces death by autophagy mediated by p53 up-regulation and β-catenin down-regulation on human hepatocellular carcinoma HuH7.5 cell line. [PDF]

Phytomedicine, 2020
Elaine da Silva Siqueira, Vírgínia Concato, Fernanda Tomiotto-Pellissier, Taylon Felipe Silva, B. Bortoleti, M. D. Gonçalves, I. N. Costa, W. V. Junior, W. Pavanelli, C. Panis, M. Mantovani, M. M. Miranda-Sapla, I. Conchon-Costa   +12 more
semanticscholar   +2 more sources

Superparamagnetic nanoparticle-catalyzed coupling of 2-amino pyridines/pyrimidines with trans-chalcones

RSC Advances, 2019
An aerobic coupling of 2-aminopyrimidines or 2-aminopyridines with trans-chalcones to afford aroylimidazo[1,2-a]pyrimidines and aroylimidazo[1,2-a]pyridines is reported.
Oanh T. K. Nguyen, Pha T. Ha, Ha V. Dang, Yen Vo, Tung T. Nguyen, Le Thi Hong Nhan, Nam T. S. Phan   +6 more
openalex   +4 more sources

Cytotoxicity of trans-chalcone and licochalcone A against breast cancer cells is due to apoptosis induction and cell cycle arrest.

Biomedicine & Pharmacotherapy, 2017
Chalcones are precursors of flavonoids that exhibit structural heterogeneity and potential antitumor activity. The objective of this study was to characterize the cytotoxicity of trans-chalcone and licochalcone A (LicoA1) against a breast cancer cell line (MCF-7) and normal murine fibroblasts (3T3).
Luis Felipe Buso Bortolotto, F. Barbosa, Gabriel Silva, T. Bitencourt, R. O. Beleboni, S. Baek, M. Marins, A. Fachin   +7 more
semanticscholar   +4 more sources

Theoretical Study on the Conformational Equilibrium of 1’, 2' and 3'-Nitro-4-hydroxy-3-methoxy Chalcone Isomers

Orbital: The Electronic Journal of Chemistry, 2021
This paper presents the conformational analysis of three chalcone compounds, 1'-nitro-4-hydroxy-3-metoxychalcoea (o-CHAL), 2'-nitro-4-hydroxy-3-metoxychalcone (m-CHAL) and 3'-nitro-4-hydroxiy3-metoxychalcone (p-CHAL).
Hualace Vinicius Emiliano, Thiago de Castro Rozada, Raphaela Pereira Guaringue, Barbara Celânia Fiorin   +3 more
doaj   +3 more sources

Phytotoxic Potential of Trans-chalcone on Crop Plants and Model Species

Journal of Plant Growth Regulation, 2013
Peer ...
Díaz-Tielas, Carla, Sotelo Pérez, Tamara, Graña, Elisa, Reigosa, Manuel J., Sánchez-Moreiras, Adela M.   +4 more
openaire   +3 more sources

Chalcones Repressed the AURKA and MDR Proteins Involved in Metastasis and Multiple Drug Resistance in Breast Cancer Cell Lines

Molecules, 2018
In the present investigation, trans-chalcone and licochalcone A were tested against MCF-7 and BT-20 breast cancer cell lines for anti-tumor activity.
Tatiana Takahasi Komoto, Tayná Minervina Bernardes, Thaís Balthazar Mesquita, Luis Felipe Buso Bortolotto, Gabriel Silva, Tamires Aparecida Bitencourt, Seung Joon Baek, Mozart Marins, Ana Lúcia Fachin   +8 more
doaj   +1 more source

The synthesis of chiral β-naphthyl-β-sulfanyl ketones via enantioselective sulfa-Michael reaction in the presence of a bifunctional cinchona/sulfonamide organocatalyst

Beilstein Journal of Organic Chemistry, 2021
Cinchona alkaloid-derived organocatalysts are widely employed in various asymmetric transformations, yielding products with high enantiopurity. In this respect, a bifunctional quinine-derived sulfonamide organocatalyst was developed to catalyze the ...
Deniz Tözendemir, Cihangir Tanyeli
doaj   +1 more source

(E)-3-(4-Methylphenyl)-1-(1,3-thiazol-2-yl)prop-2-en-1-one

Acta Crystallographica Section E, 2012
In the title chalcone, C13H11NOS, derived from the condensation of p-tolualdehyde and 1-(1,3-thiazol-2-yl)ethanone, the olefine group has a trans configuration. No classical hydrogen bonding is present in the crystal structure.
Annamalai Palaniappan, Arumugam Arulmozhivarman, Rajamanickam Ramachandran, Subramanian Srinivasan, Sivakolunthu Senthan   +4 more
doaj   +1 more source

(2E,4E)-1-(2-Hydroxyphenyl)-5-phenylpenta-2,4-dien-1-one

Acta Crystallographica Section E, 2011
In the structure of the title chalcone, C17H14O2, derived from cinnamaldehyde, the olefine group has a trans configuration. The molecular conformation is stabilized by an intramolecular O—H...O hydrogen-bond interaction with graph-set motif S(6)
W. A. Silva, C. C. Gatto, G. R. Oliveira
doaj   +1 more source