Results 121 to 130 of about 2,530 (148)

Advanced in vitro cardiac models for drug evaluation: integration of organoids, engineered tissues, and microphysiological systems. [PDF]

Microsyst Nanoeng
Kim YH, Son YH, Choi Y, Kim MS, Park SJ, Lee KY.   +5 more
europepmc   +1 more source

The Transcription Factor Mtf-1 Is Essential for Basal and Heavy Metal-Induced Metallothionein-I Gene-Expression

, 1994
Freddy Radtke, Rainer Heuchel, O.I. Georgiev, Gerlinde Stark, Michel Aguet, Walter Schaffner   +5 more
openalex   +1 more source

SENP1 mediates zinc-induced ZnT6 deSUMOylation at Lys-409 involved in the regulation of zinc metabolism in Golgi apparatus. [PDF]

Cell Mol Life Sci
Song CC, Liu T, Hogstrand C, Zhong CC, Zheng H, Sun LH, Luo Z.   +6 more
europepmc   +1 more source

Predisposition to mouse thymic lymphomas in response to ionizing radiation depends on variant alleles encoding metal-responsive transcription factor-1 (Mtf-1)

, 2005
康 田村
openalex   +1 more source

Impact of sex hormones on postoperative outcomes in plastic surgery: a narrative review. [PDF]

Front Surg
Lv X, Xiang C, Zheng Y, Lv X, Zhou W, Zhu J.   +5 more
europepmc   +1 more source

Zinc suppresses Stat3-driven IL-6 production in primary mouse adipocytes. [PDF]

Front Immunol
Chung H, Eom J, Damen MS, Stankiewicz TE, Sawada K, Alarcon PC, Ulanowicz CJ, Wayland JL, Deepe GS, Divanovic S.   +9 more
europepmc   +1 more source

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Characterization of the MTF-1 transcription factor from zebrafish and trout cells

Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology, 2000
The metal response element (MRE)-binding transcription factor-1, MTF-1, is a zinc-responsive protein that controls transcription of metallothionein (MT) genes in many cell types. In addition, MTF-1 is also hypothesized to regulate transcription of a battery of genes involved in the defense against oxidative stress.
Timothy P Dalton, Daniel W Nebert, Michael J Carvan   +2 more
exaly   +3 more sources

Understanding the mechanisms of zinc-sensing by metal-response element binding transcription factor-1 (MTF-1)

Archives of Biochemistry and Biophysics, 2007
The regulation of divalent zinc has been observed in a wide range of organisms. Since this metal is an essential nutrient, but also toxic in excess, zinc homeostasis is crucial for normal cellular functioning. The metal-responsive-element-binding transcription factor-1 (MTF-1) is a key regulator of zinc in higher eukaryotes ranging from insects to ...
John H Laïty, Glen K Andrews
exaly   +3 more sources

Regulation of malignant progression by the hypoxia-sensitive transcription factors HIF-1α and MTF-1

Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology, 2004
Solid tumors are known to develop microenvironmental hypoxia or anoxia due to malfunction and malformation of blood vessels and the energy demands of the highly proliferative tumor cells. Oxygen deprivation can cause aberrant modifications of signaling pathways and their downstream transcription factors that are believed to contribute to malignancy ...
Brian J Murphy
exaly   +3 more sources