Results 161 to 170 of about 5,388 (199)

mRNA Vaccines in Melanoma Immunotherapy-A Narrative Review. [PDF]

open access: yesCells
Plewa P   +4 more
europepmc   +1 more source

The Transcription Factor Mtf-1 Is Essential for Basal and Heavy Metal-Induced Metallothionein-I Gene-Expression

open access: green, 1994
Freddy Radtke   +5 more
openalex   +1 more source

Genome-wide CRISPR base-editing screening defines drug response networks in Leishmania

open access: yes
del Angel JA   +12 more
europepmc   +1 more source

Understanding the mechanisms of zinc-sensing by metal-response element binding transcription factor-1 (MTF-1)

Archives of Biochemistry and Biophysics, 2007
The regulation of divalent zinc has been observed in a wide range of organisms. Since this metal is an essential nutrient, but also toxic in excess, zinc homeostasis is crucial for normal cellular functioning. The metal-responsive-element-binding transcription factor-1 (MTF-1) is a key regulator of zinc in higher eukaryotes ranging from insects to ...
John H, Laity, Glen K, Andrews
openaire   +4 more sources

Metal Response Element (MRE)-Binding Transcription Factor-1 (MTF-1): Structure, Function, and Regulation

open access: closedAntioxidants & Redox Signaling, 2001
Metal-responsive control of the expression of genes involved in metal metabolism and metal homeostasis allows an organism to tightly regulate the free or bioavailable concentration of beneficial metal ions, such as zinc, copper, and iron, within an acceptable range, while efficiently removing nonbeneficial or toxic metals.
David Giedroc, Xiaohua Chen, Julius Apuy
openalex   +3 more sources

Characterization of the MTF-1 transcription factor from zebrafish and trout cells

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 2000
The metal response element (MRE)-binding transcription factor-1, MTF-1, is a zinc-responsive protein that controls transcription of metallothionein (MT) genes in many cell types. In addition, MTF-1 is also hypothesized to regulate transcription of a battery of genes involved in the defense against oxidative stress.
T P, Dalton   +3 more
openaire   +2 more sources

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