Results 61 to 70 of about 2,530 (148)

The splicing inhibitor isoginkgetin induces transcription of metallothionein genes through the metal responsive transcription factor MTF-1

Claire Peneycad
openalex   +3 more sources

Rapid Genetic Stabilisation of Transgenic and Edited Wheat Through Transformation of Immature Haploid Embryos

Plant Biotechnology Journal, Volume 24, Issue 4, Page 2143-2152, April 2026.
ABSTRACT Wheat is one of the globally important food crops, but its genetically modified application lags behind other staple crops due to its complex genome and low transformation efficiency. Normally, traditional transgenic and gene‐edited wheat requires multiple selfing generations for obtaining homozygous lines, which delayed the development of ...
Zhiyang Han, Buquan Zhao, Ming Fan, Shuangxi Zhang, Hao Peng, Xi Li, Surong Wang, Weihong Huang, Xingyu Yao, Chunwu Yang, Ke Wang, Xingguo Ye, Huali Tang   +12 more
wiley   +1 more source

Parkin mutant in the fly is largely rescued by metal-responsive transcription factor (MTF-1)

, 2011
The gene for Parkin, an E3 ubiquitin ligase, is mutated in some familial forms of Parkinson's disease, a severe neurodegenerative disorder. A homozygous mutant of the Drosophila ortholog of human parkin is viable but results in severe motoric impairment including an inability to fly, female and male sterility, and a decreased lifespan.
Saini, N, Georgiev, O, Schaffner, W
openaire   +1 more source

Generation of an Induced Pluripotent Stem Cell‐Derived Alveolar Type II In Vitro Model to Study Influenza A Virus Infection and Drug Treatments

Advanced Healthcare Materials, Volume 15, Issue 11, 20 March 2026.
Patient‐specific induced pluripotent stem cells (iPSCs) can be differentiated into alveolar type II cells (iAT2s), expanded as 3D alveolospheres, and grown at physiologically relevant air–liquid interface (ALI). This study shows for the first time the infectability of iAT2s by the influenza A virus (IAV) and proves their responsiveness to the well ...
Lena Gauthier, Hristina Koceva, Yann Bachelot, Rosanne W. Koutstaal, Puck B. van Kasteren, Marc Thilo Figge, Christian Eggeling, Alexander Sandy Mosig   +7 more
wiley   +1 more source

Advances in the role of membrane-bound transcription factors in carcinogenesis and therapy

Discover Oncology
Protein shuttling between the cytoplasm and nucleus is a unique phenomenon in eukaryotic organisms, integral to various cellular functions. Membrane-bound transcription factors (MTFs), a specialized class of nucleocytoplasmic shuttling proteins, are ...
JiaLi Deng, Jie Zhou, BinYuan Jiang
doaj   +1 more source

How Supply Networks Influence Sustainable Innovation: Evidence From Ghana's Public Works Procurement

Business Strategy and the Environment, Volume 35, Issue 3, Page 4309-4327, March 2026.
ABSTRACT Recent environmental and sustainability standards in procurement increase short‐term production and operational costs to suppliers, which are often recouped by charging price premiums for innovative solutions. However, public buyers are less likely to pay such price premiums, resulting in a disincentive among suppliers to bid for innovation ...
Peter Adjei‐Bamfo, Hadrian Geri Djajadikerta, Kerry Brown, Ferry Jie, Reza Kiani Mavi, Alain Neher   +5 more
wiley   +1 more source

Antimicrobial Resistance in Salmonella Across Aquaculture, Seafood and Related Aquatic Environments: A Scoping Review With Exploratory Textual Analysis

Reviews in Aquaculture, Volume 18, Issue 2, March 2026.
This scoping review with textual analysis maps antimicrobial resistance in Salmonella across aquaculture, seafood, and related aquatic environments. Across 93 studies, recurrent MDR patterns suggest sentinel serotypes (S. Typhimurium, S. Newport) and a minimal antimicrobial susceptibility testing (AST) panel to guide matrix‐stratified One Health ...
Cristiane Coimbra de Paula, Yuri Duarte Porto, Vinícius Silva Castro, Érica do Carmo Dias Matos, Adelino Cunha‐Neto, Ricardo César Tavares Carvalho, Luciana Kimie Savay‐da‐Silva, Eduardo Eustáquio de Souza Figueiredo, Tathiana Ferguson Motheo   +8 more
wiley   +1 more source

Zinc antagonizes cadmium-induced osteoporosis in mice by inhibiting Cd2+ deposition, enhancing antioxidant capacity and correcting bone metabolic disorders

Ecotoxicology and Environmental Safety
Chronic cadmium (Cd) exposure is a recognized risk factor for osteoporosis. Zinc (Zn) plays crucial roles in bone metabolism, yet intervention roles of Zn2+ against Cd-induced osteoporosis are incompletely understood.
Yingze Qin, Lisha Fan, Yi Feng, Ding Zhang, Chuan Xiang   +4 more
doaj   +1 more source

CircTspan3 Promotes Cartilage Development Through ANNEXIN A2‐Mediated Ferroptosis and Apoptosis Inhibition and Exosome‐Mediated Paracrine Signaling

Advanced Science, Volume 13, Issue 10, 18 February 2026.
This study reveals that XBP1s drives production of circTspan3, a circular RNA that strengthens cartilage by boosting anabolic activity and limiting cell death. Phosphorylated ANXA2 directs circTspan3 into exosomes, enabling paracrine repair. Exosomal circTspan3 expands growth‐plate cartilage and promotes in vivo regeneration, highlighting its promise ...
Yiming Pan, Fengmei Zhang, Jiayan Zhong, Qian Gong, Nana Geng, Biao Kuang, Qiumei Lan, Miao Yi, Qiqi Zeng, Cheng Chen, Mengtian Fan, Chunliang Zhao, Deping Zeng, Yu Du, Mao Nie, Zhibiao Wang, Fengjin Guo   +16 more
wiley   +1 more source

Molecular Mechanism of ZjWRKY40‐zju‐miR157 Module Regulating Phytoplasma Tolerance in Jujube

Molecular Plant Pathology, Volume 27, Issue 2, February 2026.
SJP4JWB regulated the ZjWRKY40‐zju‐miR157 module to modulate the differential phytoplasma tolerance between phytoplasma‐susceptible genotype Fu and phytoplasma‐tolerant genotype T13. ABSTRACT Phytoplasma (‘Candidatus Phytoplasma’), a bacterial pathogen, is a significant plant health concern worldwide, resulting in substantial economic losses. In jujube
Changfeng Ai, Lixin Wang, Zhi Luo, Yunjie Wang, Xuan Zhao, Lili Wang, Jiaqi Sun, Kunyi Lv, Xueqing Yan, Haonan Cao, Noor Muhammad, Qiong Zhang, Mengjun Liu, Zhiguo Liu   +13 more
wiley   +1 more source