Molecular Mechanism of ZjWRKY40‐zju‐miR157 Module Regulating Phytoplasma Tolerance in Jujube
SJP4JWB regulated the ZjWRKY40‐zju‐miR157 module to modulate the differential phytoplasma tolerance between phytoplasma‐susceptible genotype Fu and phytoplasma‐tolerant genotype T13. ABSTRACT Phytoplasma (‘Candidatus Phytoplasma’), a bacterial pathogen, is a significant plant health concern worldwide, resulting in substantial economic losses. In jujube
Changfeng Ai +13 more
wiley +1 more source
Polymorphism, selection and tandem duplication of transferrin genes in Atlantic cod (Gadus morhua) - Conserved synteny between fish monolobal and tetrapod bilobal transferrin loci [PDF]
Background The two homologous iron-binding lobes of transferrins are thought to have evolved by gene duplication of an ancestral monolobal form, but any conserved synteny between bilobal and monolobal transferrin loci remains unexplored ...
Andersen, Øivind +5 more
core +1 more source
Abstract Despite advances in targeted therapies, treatment of chronic lymphocytic leukemia (CLL) remains challenging, highlighting the urgent need for effective new therapeutic strategies. Although chimeric antigen receptor (CAR) T‐cell therapy dramatically improved outcomes in acute lymphoblastic leukemia (ALL), its efficacy in CLL is limited.
Janin Dingfelder +15 more
wiley +1 more source
Prolactin signaling through the short isoform of the mouse prolactin receptor regulates DNA binding of specific transcription factors, often with opposite effects in different reproductive issues [PDF]
Background It has been well established that prolactin (PRL) signals through the long form of its receptor (PRL-RL) and activates the Jak/Stat pathway for transcription of PRL target genes.
Y Sangeeta Devi +6 more
core +2 more sources
Identification of miRNA Biomarkers Associated With Staphylococcal Musculoskeletal Infections
ABSTRACT Musculoskeletal infections (MSKIs) pose significant challenges in orthopedic surgery. These infections are often caused by Staphylococcus aureus and S. epidermidis. Early diagnosis is crucial, as it allows prompt treatment before the infection becomes chronic and more difficult to manage.
Claudia Siverino +9 more
wiley +1 more source
A Guide to Human Zinc Absorption: General Overview and Recent Advances of In Vitro Intestinal Models [PDF]
Zinc absorption in the small intestine is one of the main mechanisms regulating the systemic homeostasis of this essential trace element. This review summarizes the key aspects of human zinc homeostasis and distribution.
Haase, Hajo, Maares, Maria
core +1 more source
ABSTRACT Cell specification and ensuing division of labor enable the accomplishment of complex tasks in multicellular organisms. In plants, mesophyll and guard cells exhibit striking functional, metabolic, and mechanophysical differences: mesophyll cells are highly specialized for efficient light‐energy conversion, whereas guard cells regulate gas ...
Friederike Hater +20 more
wiley +1 more source
Copper sensing function of Drosophila metal-responsive transcription factor-1 is mediated by a tetranuclear Cu(I) cluster [PDF]
Drosophila melanogaster MTF-1 (dMTF-1) is a copper-responsive transcriptional activator that mediates resistance to Cu, as well as Zn and Cd. Here, we characterize a novel cysteine-rich domain which is crucial for sensing excess intracellular copper by ...
Balamurugan, Kuppusamy +8 more
core
Angiotensin II upregulates the expression of placental growth factor in human vascular endothelial cells and smooth muscle cells [PDF]
Background Atherosclerosis is now recognized as a chronic inflammatory disease. Angiotensin II (Ang II) is a critical factor in inflammatory responses, which promotes the pathogenesis of atherosclerosis.
Pingxi Pan +7 more
core +2 more sources

