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Optimization of Cdx Transcription Factors Characteristics
This study presents a new application of TOPSIS for the optimization of transcription factors characteristics. This application is essential as it can help compare the characteristics of these proteins and determine the optimized output of their ...
Javanbakht T.
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Insulin-Responsive Transcription Factors
The hormone insulin executes its function via binding and activating of the insulin receptor, a receptor tyrosine kinase that is mainly expressed in skeletal muscle, adipocytes, liver, pancreatic β-cells, and in some areas of the central nervous system ...
Gerald Thiel+2 more
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Transcription factors organize into functional groups on the linear genome and in 3D chromatin
Transcription factors (TFs) and their binding sites have evolved to interact cooperatively or competitively with each other. Here we examine in detail, across multiple cell lines, such cooperation or competition among TFs both in sequential and spatial ...
Rakesh Netha Vadnala+3 more
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FOXO transcription factors [PDF]
What are they? FOXO proteins are a subgroup of the Forkhead family of transcription factors. This family is characterized by a conserved DNA-binding domain (the ‘Forkhead box’, or FOX) and comprises more than 100 members in humans, classified from FOXA to FOXR on the basis of sequence similarity.
Matthew E. Carter, Anne Brunet
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In vivo delivery of transcription factors with multifunctional oligonucleotides. [PDF]
Therapeutics based on transcription factors have the potential to revolutionize medicine but have had limited clinical success as a consequence of delivery problems. The delivery of transcription factors is challenging because it requires the development
Aran, Kiana+9 more
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The mammalian PBAF subfamily of SWI/SNF chromatin remodeling complexes plays a wide role in the regulation of gene expression. PHF10 is a subunit of the signature module of PBAF, responsible for its interaction with chromatin.
Andrey A. Sheynov+5 more
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Grapevine WRKY transcription factors
Grape is one of the most economically important fruits and is cultivated worldwide, but the viticulture faces challenges of various biotic and abiotic stresses.
Wei Wu, Peining Fu, Jiang Lu
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Immunoexpression of stem cell markers SOX-2, NANOG AND OCT4 in ameloblastoma [PDF]
Background Ameloblastoma (AME) is characterized by a locally invasive growth pattern. In an attempt to justify the aggressiveness of neoplasms, the investigation of the role of stem cells has gained prominence.
Karolyny Martins Balbinot+10 more
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TRANSCRIPTION FACTORS IN CEREBELLAR DEVELOPMENT [PDF]
The cerebellar germ arises from the rhombic lip, and it’s a rostral part from the mesencephalon. The following cellular processes take place in the developing cerebellum: proliferation, migration, differentiation, synapse formation and cell death.
I. Velikov
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Mycobacterium tuberculosis encodes ~200 transcription factors that modulate gene expression under different microenvironments in the host. Even though high-throughput chromatin immunoprecipitation sequencing and transcriptome sequencing (RNA-seq) studies
Suresh Kumar+11 more
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