Results 11 to 20 of about 15,365,257 (385)

Optimization of Cdx Transcription Factors Characteristics

open access: yesЖурнал інженерних наук, 2023
This study presents a new application of TOPSIS for the optimization of transcription factors characteristics. This application is essential as it can help compare the characteristics of these proteins and determine the optimized output of their ...
Javanbakht T.
doaj   +1 more source

Insulin-Responsive Transcription Factors

open access: yesBiomolecules, 2021
The hormone insulin executes its function via binding and activating of the insulin receptor, a receptor tyrosine kinase that is mainly expressed in skeletal muscle, adipocytes, liver, pancreatic β-cells, and in some areas of the central nervous system ...
Gerald Thiel   +2 more
doaj   +1 more source

Transcription factors organize into functional groups on the linear genome and in 3D chromatin

open access: yesHeliyon, 2023
Transcription factors (TFs) and their binding sites have evolved to interact cooperatively or competitively with each other. Here we examine in detail, across multiple cell lines, such cooperation or competition among TFs both in sequential and spatial ...
Rakesh Netha Vadnala   +3 more
doaj   +1 more source

FOXO transcription factors [PDF]

open access: yesCurrent Biology, 2007
What are they? FOXO proteins are a subgroup of the Forkhead family of transcription factors. This family is characterized by a conserved DNA-binding domain (the ‘Forkhead box’, or FOX) and comprises more than 100 members in humans, classified from FOXA to FOXR on the basis of sequence similarity.
Matthew E. Carter, Anne Brunet
openaire   +3 more sources

In vivo delivery of transcription factors with multifunctional oligonucleotides. [PDF]

open access: yes, 2015
Therapeutics based on transcription factors have the potential to revolutionize medicine but have had limited clinical success as a consequence of delivery problems. The delivery of transcription factors is challenging because it requires the development
Aran, Kiana   +9 more
core   +6 more sources

The sequential phosphorylation of PHF10 subunit of the PBAF chromatin-remodeling complex determines different properties of the PHF10 isoforms

open access: yesBiology Open, 2020
The mammalian PBAF subfamily of SWI/SNF chromatin remodeling complexes plays a wide role in the regulation of gene expression. PHF10 is a subunit of the signature module of PBAF, responsible for its interaction with chromatin.
Andrey A. Sheynov   +5 more
doaj   +1 more source

Grapevine WRKY transcription factors

open access: yesFruit Research, 2022
Grape is one of the most economically important fruits and is cultivated worldwide, but the viticulture faces challenges of various biotic and abiotic stresses.
Wei Wu, Peining Fu, Jiang Lu
doaj   +1 more source

Immunoexpression of stem cell markers SOX-2, NANOG AND OCT4 in ameloblastoma [PDF]

open access: yesPeerJ, 2023
Background Ameloblastoma (AME) is characterized by a locally invasive growth pattern. In an attempt to justify the aggressiveness of neoplasms, the investigation of the role of stem cells has gained prominence.
Karolyny Martins Balbinot   +10 more
doaj   +2 more sources

TRANSCRIPTION FACTORS IN CEREBELLAR DEVELOPMENT [PDF]

open access: yesTrakia Journal of Sciences, 2023
The cerebellar germ arises from the rhombic lip, and it’s a rostral part from the mesencephalon. The following cellular processes take place in the developing cerebellum: proliferation, migration, differentiation, synapse formation and cell death.
I. Velikov
doaj   +1 more source

Mycobacterium tuberculosis Transcription Factor EmbR Regulates the Expression of Key Virulence Factors That Aid in Ex Vivo and In Vivo Survival

open access: yesmBio, 2022
Mycobacterium tuberculosis encodes ~200 transcription factors that modulate gene expression under different microenvironments in the host. Even though high-throughput chromatin immunoprecipitation sequencing and transcriptome sequencing (RNA-seq) studies
Suresh Kumar   +11 more
doaj   +1 more source

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