Results 31 to 40 of about 5,538,535 (384)
Strong negative self regulation of Prokaryotic transcription factors increases the intrinsic noise of protein expression [PDF]
, 2008 Background Many prokaryotic transcription factors repress their own transcription. It is often asserted that such regulation enables a cell to homeostatically maintain protein abundance.
A Bar-Even +35 more
core +4 more sources
Structure and function of negative feedback loops at the interface of genetic and metabolic networks [PDF]
, 2006 The molecular network in an organism consists of transcription/translation regulation, protein-protein interactions/modifications and a metabolic network, together forming a system that allows the cell to respond sensibly to the multiple signal molecules
Andersson, Anna M. C. +3 more
core +4 more sources
Transcriptional regulation at a glance [PDF]
BMC Bioinformatics, 2007 Considering that 80 genomes have been sequenced, providing us with the static information of the genome, it is still a long way to reveal the relationship between complex genotypes and phenotypes. The transcriptional regulation process is one of the obstacles that need to be understood to bridge our current information gap.
openaire +5 more sources
The grammar of transcriptional regulation [PDF]
Human Genetics, 2014 Eukaryotes employ combinatorial strategies to generate a variety of expression patterns from a relatively small set of regulatory DNA elements. As in any other language, deciphering the mapping between DNA and expression requires an understanding of the set of rules that govern basic principles in transcriptional regulation, the functional elements ...
Shira Weingarten-Gabbay, Eran Segal
openaire +3 more sources
Regulation of transcription elongation in response to osmostress [PDF]
, 1967 Cells trigger massive changes in gene expression upon environmental fluctuations. The Hog1 stress-activated protein kinase (SAPK) is an important regulator of the transcriptional activation program that maximizes cell fitness when yeast cells are exposed
Begley, Victoria Sarah +7 more
core +3 more sources
The transcriptional regulation of pluripotency [PDF]
Cell Research, 2012 The defining features of embryonic stem cells (ESCs) are their self-renewing and pluripotent capacities. Indeed, the ability to give rise into all cell types within the organism not only allows ESCs to function as an ideal in vitro tool to study embryonic development, but also offers great therapeutic potential within the field of regenerative medicine.
Yeo, Jia-Chi, Ng, Huck-Hui
openaire +4 more sources
Understanding the role of chromatin remodeling in the regulation of circadian transcription in Drosophila. [PDF]
, 2015 Circadian clocks enable organisms to anticipate daily changes in the environment and coordinate temporal rhythms in physiology and behavior with the 24-h day-night cycle. The robust cycling of circadian gene expression is critical for proper timekeeping,
Chiu, Joanna C +2 more
core +1 more source
Regulation and Role of Transcription Factors in Osteogenesis
International Journal of Molecular Sciences, 2021 Bone is a dynamic tissue constantly responding to environmental changes such as nutritional and mechanical stress. Bone homeostasis in adult life is maintained through bone remodeling, a controlled and balanced process between bone-resorbing osteoclasts ...
W. C. Chan +3 more
semanticscholar +1 more source
Transcriptional and Post-Transcriptional Regulation and Transcriptional Memory of Chromatin Regulators in Response to Low Temperature [PDF]
Frontiers in Plant Science, 2019 AbstractChromatin regulation ensures stable repression of stress-inducible genes under non-stress conditions and transcriptional activation and memory of such an activation of those genes when plants are exposed to stress. However, there is only limited knowledge on how chromatin genes are regulated at the transcriptional and post-transcriptional level
Vyse, K. +6 more
openaire +7 more sources
Selective Activation of Alternative MYC Core Promoters by Wnt-Responsive Enhancers. [PDF]
, 2018 In Metazoans, transcription of most genes is driven by the use of multiple alternative promoters. Although the precise regulation of alternative promoters is important for proper gene expression, the mechanisms that mediates their differential ...
Bardales, Jorge A +4 more
core +3 more sources