Results 201 to 210 of about 242,580 (255)

CRISPR Interference to Inhibit Oncogenes for Cancer Therapy. [PDF]

Int J Mol Sci
Guo B.
europepmc   +1 more source

RNA‐Binding Protein RBM25 Targets the mRNA Stability of GTPase Rab22a to Restrict Viral Entry and Infection

Advanced Science, EarlyView.
This study identifies RNA‐binding protein RBM25 as a broad‐spectrum antiviral factor acting independently of type I interferon. It blocks viral entry by suppressing GTPase Rab22a via the RC3H1‐mediated destabilization of Rab22a mRNA. Viral downregulation of RBM25 enhances GTPase Rab22a expression and viral entry, revealing an unreported post ...
Yingying Ding, Huiying Chen, Yuyu Jiang, Chunyan Zhao, Jie Bai, Yan Xiang, Zeting Wang, Xixi Wang, Bing Rui, Wanda Tang, Yue Ding, Zhenzhen Zhan, Yunkai Zhang, Xingguang Liu   +13 more
wiley   +1 more source

Transcriptomic Meta-Analysis and Functional Validation Identify Long Non-Coding RNAs as Modulators of Zika Virus-Mediated Oncolysis in Glioblastoma Multiforme Cell Lines. [PDF]

Cells
Singh S, Gerlein M, Horvath AR, Henderson L, Hwang EI, Packer RJ, Shao C, Kousa YA, Mansour TA.   +8 more
europepmc   +1 more source

Block-and-Lock Approaches for HIV Cure: Mechanistic Insights, Challenges, and Emerging Role of CPSF6. [PDF]

Int J Mol Sci
Tolomeo M, Cascio A.
europepmc   +1 more source

Small RNAs as systemic signals in plant defense: mechanisms, challenges, and future directions. [PDF]

Mol Biol Rep
Wekesa C, Kiprotich K, Muoma J, Mithöfer A.   +3 more
europepmc   +1 more source

CaNAC61, CaNAC79, and CaNAC92 Act as Negative Regulators in Pepper Defense Response Against <i>Phytophthora capsici</i>. [PDF]

Biology (Basel)
Wang Y, Chu M, Gong B, Li X, Wang J, Azeem M, Li Y, Cheng W.   +7 more
europepmc   +1 more source

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Post-transcriptional gene silencing in plants

Current Opinion in Cell Biology, 1997
Overexpression of chimeric transgenes in plants can trigger post-transcriptional gene silencing that is dependent on epigenetic information and physiological conditions. The current view is that unproductive RNA serves as a crucial signal for gene silencing, although direct evidence is lacking for this theory.
Ann Depicker, Marc Van Montagu
exaly   +3 more sources

Post-transcriptional gene silencing in plants by RNA

Plant Cell Reports, 2003
RNA silencing, which is termed post-transcriptional gene silencing in plants, is an RNA degradation process through sequence-specific nucleotide interactions induced by double-stranded RNA. In plants, RNA silencing not only serves as a component of the defense mechanism, but also participates in the regulation of endogenous gene expression in a variety
Prakash Kumar
exaly   +3 more sources

Transcriptional gene silencing as a tool for uncovering gene function in maize

Plant Journal, 2005
SummaryTranscriptional gene silencing has broad applications for studying gene function in planta. In maize, a large number of genes have been identified as tassel‐preferred in their expression pattern, both by traditional genetic methods and by recent high‐throughput expression profiling platforms.
Erica Unger-Wallace
exaly   +3 more sources