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Low-level illegitimate transcription of genes may be to silence the genes
Biochemical and Biophysical Research Communications, 2005In yeast and plants, low level transcription of a gene is recently revealed to be required to repress the gene. It may account for the widely low level illegitimate transcriptions of tissue-specific genes reported in mammalian cells. This hypothetical link gives insight into both analysis of transcription-associated evolutionary events and further ...
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RNA-Mediated Transcriptional Gene Silencing in Human Cells
2008The utilization of small interfering RNAs (siRNAs) represents a new paradigm in gene knockout technology. siRNAs can be used to knockdown the expression of a particular gene by targeting the mRNA in a post-transcriptional manner. While there are a plethora of reports applying siRNA-mediated post-transcriptional silencing (PTGS) therapeutically there ...
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Temperature Modulates Virus-Induced Transcriptional Gene Silencing via Secondary Small RNAs
New Phytologist, 2021Attila Molnar, Douglas E Pyott, Yue Fei
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Transcriptional Gene Silencing in Plants: Targets, Inducers and Regulators
Trends in Genetics, 2001Hervé Vaucheret, Mathilde Fagard
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Promoter‐Specific Transcriptional Interference and c‐Myc Gene Silencing by siRNAs in Human Cells
EMBO Journal, 2009Sara Napoli +2 more
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Suppression of Post‐Transcriptional Gene Silencing by a Plant Viral Protein Localized in the Nucleus
EMBO Journal, 2000Hui-Shan Guo +2 more
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